Intracellular targeting therapy of cisplatin‐encapsulated transferrin‐polyethylene glycol liposome on peritoneal dissemination of gastric cancer

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

1986 • 6,585 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

1978 • 2,254 citations

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

1990 • 1,962 citations

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

1991 • 1,370 citations

Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft.

1994 • 904 citations

The physiology of transferrin and transferrin receptors.

1987 • 586 citations

Long-circulating (sterically stabilized) liposomes for targeted drug delivery

1994 • 449 citations

Liposomes: From Biophysics to Therapeutics

1989 • 342 citations

Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice

1999 • 308 citations

Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis

1994 • 278 citations

Liposomal Drug Formulations

1998 • 274 citations

TRANSFERRIN AND TRANSFERRIN RECEPTORS IN CARCINOMA OF THE BREAST

1980 • 272 citations

Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol) s conjugated at their distal terminals to monoclonal antibodies

1995 • 262 citations

Liposomes: From Biophysics to Therapeutics

1991 • 246 citations

Prolonged circulation time in vivo of large unilamellar liposomes composed of distearoyl phosphatidylcholine and cholesterol containing amphipathic poly(ethylene glycol)

1992 • 227 citations

Possibility of active targeting to tumor tissues with liposomes

1999 • 211 citations

Immunoliposomes bearing polyethyleneglycol‐coupled Fab′ fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo

1997 • 168 citations

Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy

1996 • 157 citations

Hyperthermo‐chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination

1991 • 138 citations

The effect of cis-diamminedichloroplatinum (II) on cultured human lymphoma cells and its therapeutic implications.

1973 • 120 citations

The Transferrin Receptor: Its Diagnostic Value and its Potential as Therapeutic Target

1993 • 117 citations

Effect of molecular weight in amphipathic polyethyleneglycol on prolonging the circulation time of large unilamellar liposomes.

1991 • 114 citations

Neoadjuvant chemotherapy for high‐grade advanced gastric cancer

1993 • 111 citations

Receptor mediated delivery of daunomycin using immunoliposomes: pharmacokinetics and tissue distribution in the rat.

1997 • 107 citations

High-volume intraperitoneal chemotherapy with methotrexate in patients with cancer.

1981 • 100 citations

Extravascular transport in normal and tumor tissues

1986 • 99 citations

Exposure of K562 cells to anti-receptor monoclonal antibody OKT9 results in rapid redistribution and enhanced degradation of the transferrin receptor.

1986 • 97 citations

Detection of tumor cells in blood using CD45 magnetic cell separation followed by nested mutant allele-specific amplification ofp53 and K-ras genes in patients with colorectal cancer

2000 • 90 citations

Role of transferrin, Fe, and transferrin receptors in myeloid leukemia cell growth. Studies with an antitransferrin receptor monoclonal antibody.

1985 • 89 citations

Pharmacology of Intraperitoneal Chemotherapy

1983 • 81 citations

LYMPHATICS AND LYMPH CIRCULATION—PHYSIOLOGY AND PATHOLOGY

1968 • 77 citations

Prolongation of Liposome Circulation Time by Various Derivatives of Polyethyleneglycols.

1996 • 51 citations

Modulation of doxorubicin resistance in a doxorubicin-resistant human leukaemia cell by an immunoliposome targeting transferring receptor

1997 • 49 citations

Comparison of the kinetics of cycling of the transferrin receptor in the presence or absence of bound diferric transferrin

1989 • 42 citations

Transferrin receptor in oral tumors

1994 • 41 citations

Comparison of the iv and ip routes of administration of cisplatin in dogs.

1981 • 37 citations

The Transferrin Receptor and the Release of Iron from Transferrin

1994 • 35 citations

Increased liposome extravasation in selected tissues: effect of substance P.

1996 • 34 citations

Pharmacologic effects of cisplatin microspheres on peritoneal carcinomatosis in rodents

1993 • 33 citations

An epitope of the transferrin receptor is exposed on the cell surface of high-grade but not low-grade human lymphomas

1989 • 30 citations

Intraoperative chemotherapy with carbon particles adsorbing mitomycin C for gastric cancer with peritoneal dissemination in rabbits.

1988 • 26 citations

Improvement of Intraperitoneal Chemotherapy for Rat Ovarian Cancer Using Cisplatin‐containing Microspheres

1996 • 17 citations

Dynamic Change of the Vascular Wall from Transmural to Intercellular Passage of Red Blood Cells Observed in Splenic Regeneration

1990 • 5 citations