Rapid re‐expression of CD45RC on rat CD4 T cells in vitro correlates with a change in function

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

Human naive and memory T cells

1988 • 793 citations

Naive and memory T cells show distinct pathways of lymphocyte recirculation.

1990 • 792 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor.

1990 • 375 citations

Interconversion of CD45R subsets of CD4 T cells in vivo

1990 • 371 citations

The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and α2–6 sialyltransferase, CD75, on B cells

1991 • 348 citations

Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

1987 • 327 citations

Molecular and antigenic heterogeneity of the rat leukocyte‐common antigen from thymocytes and T and B lymphocytes

1985 • 286 citations

Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation

1988 • 281 citations

Differential activation requirements for virgin and memory T cells.

1988 • 271 citations

The synergy between naive and memory T cells during activation

1991 • 247 citations

MRC OX-22, a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen.

1983 • 243 citations

Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells.

1990 • 236 citations

Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4⁺ T cells

1991 • 218 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.

1988 • 218 citations

The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation.

1988 • 213 citations

Cyclic regulation of CD45 isoform expression in a long term human CD4+CD45RA+ T cell line.

1991 • 186 citations

Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation.

1989 • 185 citations

The stable and permanent expansion of functional T lymphocytes in athymic nude rats after a single injection of mature T cells.

1987 • 173 citations

Activation signals regulate heat shock transcription factor 1 in human B lymphocytes

1997 • 169 citations

Phenotypic and functional heterogeneity of CD4+ T cells

1988 • 142 citations

The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45.

1988 • 130 citations

Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells.

1990 • 127 citations

The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype.

1989 • 125 citations

Expression of soluble isoforms of rat CD45. Analysis by electron microscopy and use in epitope mapping of anti-CD45R monoclonal antibodies.

1992 • 87 citations

Memory CD4+ T cells in man form two distinct subpopulations, defined by their expression of isoforms of the leucocyte common antigen, CD45.

1990 • 80 citations

Loss of activation-induced CD45RO with maintenance of CD45RA expression during prolonged culture of T cells and NK cells.

1991 • 73 citations

Functional maturation of recent thymic emigrants in the periphery: Development of alloreactivity correlates with the cyclic expression of CD45RC isoforms

1992 • 64 citations

High molecular weight lymphocyte surface proteins are structurally related and are expressed on different cell populations at different times during lymphocyte maturation and differentiation.

1982 • 58 citations

Genetically determined lack of CD45R- T cells in healthy individuals. Evidence for a regulatory polymorphism of CD45R antigen expression.

1990 • 58 citations

CD45 alternative exon expression in murine and human CD4+ T cell subsets.

1992 • 52 citations

Function of CD4 T cell subsets in vivo: expression of CD45R isoforms.

1992 • 44 citations

CD45R CD4 T cell subset‐reconstituted nude rats: subset‐dependent survival of recipients and bi‐directional isoform switching

1991 • 43 citations

Human CD4⁺CD45RO⁺ and CD4⁺CD45RA⁺ T cells synergize in response to alloantigens

1991 • 41 citations

The coexpression of CD45RA and CD45RO isoforms on T cells during the S/G2/M stages of cell cycle

1991 • 35 citations

Allorecognition of HLA‐DR and ‐DQ transfectants by human CD45RA and CD45R0 CD4 T cells: Repertoire analysis and activation requirements

1991 • 28 citations

Allograft rejection in athymic nude rats by transferred T-cell subsets. I. The response of naive CD4+ and CD8+ thoracic duct lymphocytes to complete allogeneic incompatibilities.

1990 • 26 citations

T-cell receptor-bearing cells from athymic nude rats respond to alloantigen in vitro but are defective in vivo.

1991 • 23 citations

The Stimulus to Host Cell Proliferation in Graft‐versus‐Host Reactions

1981 • 13 citations

The cyclic expression of CD45R isoforms on CD4 T cells

1992 • 9 citations