Enhanced Tumor Protection by Granulocyte-Macrophage Colony-Stimulating Factor Expression at the Site of an Allogeneic Vaccine

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

Biological behavior of malignant melanoma cells correlated to their survival in vivo.

1975 • 586 citations

Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.

1975 • 573 citations

Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer

1998 • 419 citations

Prolongation of Survival in Metastatic Melanoma After Active Specific Immunotherapy With a New Polyvalent Melanoma Vaccine

1992 • 410 citations

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product.

1996 • 386 citations

Paracrine Cytokine Adjuvants in Cancer Immunotherapy

1995 • 373 citations

Costimulation of T cells for tumor immunity

1993 • 324 citations

Minor H Antigens Introduced on H-2 Different Stimulating Cells Cross-React at the Cytotoxic T Cell Level during in Vivo Priming

1976 • 253 citations

Interleukin 6 gene transfection into Lewis lung carcinoma tumor cells suppresses the malignant phenotype and confers immunotherapeutic competence against parental metastatic cells.

1992 • 232 citations

In Vivo Cross-Priming of MHC Class I–Restricted Antigens Requires the TAP Transporter

1996 • 225 citations

Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules.

1993 • 206 citations

In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression.

1994 • 196 citations

Dendritic cells and immune-based therapies.

1996 • 180 citations

Antigen presentation to cytotoxic T lymphocytes in vivo.

1995 • 168 citations

Tumor-specific immunogenicity of stress-induced proteins: convergence of two evolutionary pathways of antigen presentation?

1991 • 105 citations

Correlation of cell-surface phenotype with the establishment of interleukin 3-dependent cell lines from wild-mouse murine leukemia virus-induced neoplasms.

1985 • 104 citations

Protective antitumor immunity induced by immunization with completely allogeneic tumor cells.

1996 • 89 citations

Identification of the Genes Encoding Cancer Antigens: Implications for Cancer Immunotherapy

1996 • 75 citations

Enhanced Immune Priming with Spatial Distribution of Paracrine Cytokine Vaccines

1996 • 67 citations

Efficient DNA-mediated transfer of selectable genes and unselected sequences into differentiated and undifferentiated mouse melanoma clones

1984 • 57 citations

Murine tumor antigens: is it worth the search?

1996 • 51 citations

Enhancement of experimental metastatic ability by tumor necrosis factor-alpha alone or in combination with interferon-gamma

1990 • 41 citations

Use of Murine Models of Cytokine-Secreting Tumor Vaccines to Study Feasibility and Toxicity Issues Critical to Designing Clinical Trials

1995 • 34 citations

The Function of the CD4 Coreceptor in the Development of T Cells

1995 • 8 citations