The taurine transporter: mechanisms of regulation

Retinal Degeneration Associated with Taurine Deficiency in the Cat

1975 • 584 citations

TAURINE: BIOLOGICAL UPDATE

1986 • 571 citations

Effects of hypernatremia on organic brain osmoles.

1990 • 343 citations

Milk protein quantity and quality in low-birth-weight infants

1977 • 308 citations

The Enterohepatic Circulation of Bile Acids in Man

1976 • 285 citations

Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain.

1992 • 276 citations

The renal handling of amino acids and oligopeptides.

1988 • 274 citations

Milk Protein Quantity and Quality in Low-Birthweight Infants: I. Metabolic Responses and Effects on Growth

1976 • 265 citations

Cloning and expression of a high affinity taurine transporter from rat brain.

1992 • 261 citations

Taurine and other free amino acids in milk of man and other mammals

1978 • 249 citations

Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice

2001 • 219 citations

Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta

1994 • 205 citations

Taurine: its biological role and clinical implications.

1985 • 205 citations

The role of cytosolic Ca2+ in cell injury, necrosis and apoptosis

1992 • 199 citations

Regulation of the Cellular Content of the Organic Osmolyte Taurine in Mammalian Cells

2003 • 190 citations

Newer concepts of the indispensable amino acids

1987 • 161 citations

Taurine: Its Biological Role and Clinical Implications

1985 • 153 citations

Taurine in Development

1988 • 134 citations

Cloning of the human taurine transporter and characterization of taurine uptake in thyroid cells

1993 • 133 citations

Milk Protein Quantity and Quality in Low-Birth-Weight Infants: II. Effects on Selected Aliphatic Amino Acids in Plasma and Urine

1977 • 125 citations

Survey of osmolytes in renal cell lines

1988 • 119 citations

Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells

2004 • 116 citations

Taurine in Pediatric Nutrition: Review and Update

1989 • 109 citations

Milk Protein Quantity and Quality in the Term Infant II. Effects on Acidic and Neutral Amino Acids

1982 • 109 citations

An ultrastructural study of nutritionally induced and reversed retinal degeneration in cats.

1975 • 104 citations

Taurine behaves as an osmolyte in Madin-Darby canine kidney cells. Protection by polarized, regulated transport of taurine.

1991 • 102 citations

Renal cortex taurine content regulates renal adaptive response to altered dietary intake of sulfur amino acids.

1985 • 94 citations

Renal adaptation to altered dietary sulfur amino acid intake occurs at luminal brushborder membrane

1983 • 91 citations

Cellular taurine release triggered by stimulation of the Fas(CD95) receptor in Jurkat lymphocytes

1998 • 80 citations

Postnatal taurine deficiency in the kitten results in a persistence of the cerebellar external granule cell layer: Correction by taurine feeding

1985 • 73 citations

Cloning of a rabbit renal Na-Pi cotransporter, which is regulated by dietary phosphate

1995 • 63 citations

Taurine depletion in very low birth weight infants receiving prolonged total parenteral nutrition: Role of renal immaturity

1990 • 62 citations

Localization of the membrane defect in transepithelial transport of taurine by parallel studies in vivo and in vitro in hypertaurinuric mice.

1976 • 58 citations

Adaptive regulation of taurine transport in two continuous renal epithelial cell lines

1990 • 57 citations

Characterization and Regulation of Taurine Transport in Caco-2, Human Intestinal Cells

1997 • 55 citations

Taurine in Pediatric Nutrition

1995 • 55 citations

Renal tubular reabsorption of taurine,?-aminobutyric acid (GABA) and?-alanine studied by continuous microperfusion

1976 • 55 citations

Sodium-coupled amino acid transport in renal tubule

1989 • 53 citations

Anion dependence of taurine transport by rat renal brush-border membrane vesicles

1989 • 53 citations

Evolutionary matches of enzyme and transporter capacities to dietary substrate loads in the intestinal brush border

1998 • 51 citations

Dietary Taurine Content and Feline Reproduction and Outcome

1991 • 51 citations

Calcium and free radicals in hypoxia/reoxygenation injury of renal epithelial cells

1994 • 48 citations

Renal adaptation to alteration in dietary amino acid intake

1983 • 43 citations

Ser-322 Is a Critical Site for PKC Regulation of the MDCKCell Taurine Transporter (pNCT)

1999 • 43 citations

Transcriptional Repression of Taurine Transporter Gene (TauT) by p53 in Renal Cells

2002 • 42 citations

Studies on Renal Adaptation to Altered Dietary Amino Acid Intake: Tissue Taurine Responses in Nursing and Adult Rats

1986 • 41 citations

Taurine as a conditionally essential nutrient in man.

1986 • 40 citations

Adaptive regulation of MDCK cell taurine transporter (pNCT) mRNA: transcription of pNCT gene is regulated by external taurine concentration

1997 • 38 citations

The taurine transporter gene and its role in renal development

2000 • 37 citations

Hypertonicity-induced accumulation of organic osmolytes in papillary interstitial cells

1999 • 36 citations

Cloning and Characterization of the Promoter Region of the Rat Taurine Transporter (TauT) Gene

2002 • 35 citations

The Relative Roles of External Taurine Concentration and Medium Osmolality in the Regulation of Taurine Transport in LLC-PK1 and MDCK Cells

1995 • 35 citations

Molecular Cloning and Functional Expression of an LLC-PK1 Cell Taurine Transporter that is Adaptively Regulated by Taurine

1998 • 29 citations

Regulation of the taurine transporter gene in the S3 segment of the proximal tubule

1997 • 28 citations

Functional Expression of Rat Renal Cortex Taurine Transporter in Xenopus laevis Oocytes: Adaptive Regulation by Dietary Manipulation

1997 • 28 citations

The renal transport of taurine and the regulation of renal sodium-chloride-dependent transporter activity

1990 • 27 citations

Role of conserved peptide in taurine transporter inactivation modulated by protein kinase C.

1996 • 26 citations

Effect of Dietary Taurine on Renal Taurine Transport by Proximal Tubule Brush Border Membrane Vesicles in the Kitten

1989 • 25 citations

Regulation of taurine transporter gene (TauT) by WT1

2003 • 24 citations

Identification of Promoter Elements Involved in Adaptive Regulation of the Taurine Transporter Gene: Role of Cytosolic Ca2+ Signaling

2002 • 23 citations

Abnormal Visual Acuity and Retinal Morphology in Rhesus Monkeys Fed a Taurine-Free Diet During the First Three Postnatal Months

1987 • 22 citations

Characteristics of Taurine Transport in Cultured Renal Epithelial Cell Lines: Asymmetric Polarity of Proximal and Distal Cell Lines

1992 • 20 citations

Regulation of TauT by cisplatin in LLC-PK1 renal cells

2005 • 18 citations

Effects of Taurine on Signal Transduction Steps Induced during Hypertrophy of Rat Heart Myocytes

1998 • 16 citations

Enhanced taurine release in cultured cerebellar granule cells in cell-damaging conditions

1999 • 14 citations

Mapping of the taurine transporter gene to mouse chromosome 6 and to the short arm of human chromosome 3

1995 • 13 citations

Renal amino acid transport: cellular and molecular events from clearance studies to frog eggs

1993 • 12 citations

Regulation of Expression of Taurine Transport in Two Continuous Renal Epithelial Cell Lines and Inhibition of Taurine Transporter by a Site-Directed Antibody

1996 • 11 citations

Efflux of taurine from renal brush border membrane vesicles: Is it adaptively regulated?

1993 • 10 citations

Expression of Taurine Transporter and its Regulation by Diet in Xenopus laevis Oocytes Following Injection of Rat Kidney Cortex mRNA

1994 • 10 citations

Taurine and failing heart: experimental and clinical aspects.

1985 • 10 citations

Membrane Fluidity and Phospholipid Composition in Relation to Sulfur Amino Acid Intake in Brush Border Membranes of Rat Kidney

1986 • 8 citations

Comparison of serum and plasma taurine values in Bengal tigers with values in taurine-sufficient and -deficient domestic cats

1990 • 6 citations

Modulation of cardiac Ca++ current by taurine.

1990 • 6 citations

Transactivation of TauT by p53 in MCF-7 Cells

2003 • 5 citations

Adaptive regulation of taurine and β-alanine uptake in a human kidney cell line from the proximal tubule

1997 • 4 citations

Gating of taurine transport: role of the fourth segment of the taurine transporter.

2003 • 2 citations

Ionic and voltage requirements for tubular taurine transport.

1990 • 2 citations

Gating of Taurine Transport

2003 • 2 citations