Conditions That Induce Tolerance in Mature CD4+ T Cells

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

1994 • 895 citations

"Infectious" Transplantation Tolerance

1993 • 890 citations

Organ-Specific Disease Provoked by Systemic Autoimmunity

1996 • 880 citations

Peripheral deletion of antigen-reactive T cells in oral tolerance

1995 • 775 citations

Peripheral Selection of the T Cell Repertoire

1991 • 666 citations

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction

1991 • 523 citations

Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

1989 • 462 citations

Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.

1991 • 450 citations

Induction of immunological paralysis in two zones of dosage

1964 • 439 citations

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor.

1994 • 418 citations

Kinetic Differences in Unresponsiveness of Thymus and Bone Marrow Cells

1971 • 374 citations

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

1994 • 353 citations

Clonal expansion precedes anergy and death of V_β8⁺ peripheral T cells responding to staphylococcal enterotoxin B in vivo

1991 • 330 citations

Induction of classical transplantation tolerance in the adult.

1989 • 325 citations

Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice.

1990 • 312 citations

A Disquisition on Suppressor T Cells

1975 • 255 citations

The anatomy of T-cell activation and tolerance.

1996 • 225 citations

Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance.

1995 • 225 citations

Studies on the Chemistry of Anaphylaxis (III). Experiments with Isolated Proteins, Especially those of the Hen's Egg

1911 • 211 citations

Maintenance of in Vivo Tolerance by Persistence of Antigen

1992 • 209 citations

Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen.

1993 • 184 citations

CD4 monoclonal antibody pairs for immunosuppression and tolerance induction

1987 • 173 citations

Effectiveness of Lipid and Lipidophilic Substances as Adjuvants

1961 • 148 citations

Oral Tolerance in Experimental Autoimmune Encephalomyelitis

1996 • 136 citations

Transplantation tolerance induced by antigen pretreatment and depleting anti‐CD4 antibody depends on CD4⁺ T cell regulation during the induction phase of the response

1995 • 134 citations

Reprogramming the Immune System for Peripheral Tolerance with CD4 and CD8 Monoclonal Antibodies

1992 • 124 citations

Presentation of a Viral T Cell Epitope Expressed in the CDR3 Region of a Self Immunoglobulin Molecule

1993 • 123 citations

Limited capacity for tolerization of CD4+ T cells specific for a pancreatic β cell neo-antigen

1995 • 121 citations

Studies on the Chemistry of Anaphylaxis

1908 • 77 citations

In vivo induction of tolerance in murine CD4+ cell subsets.

1993 • 68 citations

Characterization of apoptosis-resistant antigen-specific T cells in vivo.

1996 • 63 citations

Transplantation tolerance with monoclonal antibodies.

1990 • 20 citations