Molecular components of the mitotic spindle

Beyond self-assembly: From microtubules to morphogenesis

1986 • 1,334 citations

γ-Tubulin is a highly conserved component of the centrosome

1991 • 566 citations

Microtubule-Associated Proteins

1986 • 559 citations

γ-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans

1990 • 558 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

KAR3, a kinesin-related gene required for yeast nuclear fusion

1990 • 504 citations

Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells.

1990 • 488 citations

Cytoplasmic dynein is localized to kinetochores during mitosis

1990 • 486 citations

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis.

1987 • 407 citations

γ-Tubulin is present in Drosophila melanogaster and homo sapiens and is associated with the centrosome

1991 • 405 citations

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans

1990 • 404 citations

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene

1990 • 366 citations

Centrosome development in early mouse embryos as defined by an autoantibody against pericentriolar material

1983 • 323 citations

Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.

1987 • 314 citations

Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

1989 • 261 citations

Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation.

1985 • 239 citations

Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin

1990 • 229 citations

The Isolation and Biochemical Characterization of the Mitotic Apparatus of Dividing Cells

1952 • 225 citations

A kinesin-like protein required for distributive chromosome segregation in Drosophila

1990 • 209 citations

The motor for poleward chromosome movement in anaphase is in or near the kinetochore.

1989 • 202 citations

Two different microtubule-based motor activities with opposite polarities in kinetochores

1991 • 202 citations

THE DISTRIBUTION OF SPINDLE MICROTUBULES DURING MITOSIS IN CULTURED HUMAN CELLS

1971 • 192 citations

Identification and characterization of a gene encoding a kinesin-like protein in Drosophila

1990 • 172 citations

Mitosis : molecules and mechanisms

1989 • 153 citations

Distribution of a matrix component of the midbody during the cell cycle in Chinese hamster ovary cells

1988 • 150 citations

The mitotic apparatus-associated 51-kDa protein from sea urchin eggs is a GTP-binding protein and is immunologically related to yeast polypeptide elongation factor 1 alpha.

1990 • 134 citations

Telophase disc: a new mammalian mitotic organelle that bisects telophase cells with a possible function in cytokinesis

1991 • 130 citations

A monoclonal antibody to a mitotic microtubule-associated protein blocks mitotic progression.

1990 • 107 citations

Localization of kinesin in cultured cells.

1988 • 107 citations

ULTRASTRUCTURE AND BIREFRINGENCE OF THE ISOLATED MITOTIC APPARATUS OF MARINE EGGS

1967 • 81 citations

A dynamin-like protein encoded by the yeast sporulation gene SP015

1991 • 80 citations

The predicted amino acid sequence of a centrosphere protein in dividing sea urchin eggs is similar to elongation factor (EF-1a)

1990 • 78 citations

Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles.

1987 • 73 citations

Membranes in the mitotic apparatus

1981 • 62 citations

225‐Kilodalton phosphoprotein associated with mitotic centrosomes in sea urchin eggs

1989 • 52 citations

Microinjection of antibodies to a 62 kd mitotic apparatus protein arrests mitosis in dividing sea urchin embryos

1989 • 47 citations

Inhibition of mitosis by an antibody to the mitotic calcium transport system

1987 • 44 citations

Mitosis in sand dollar embryos is inhibited by antibodies directed against the calcium transport enzyme of muscle.

1986 • 40 citations

An antigen located in the kinetochore region in metaphase and on polar microtubule ends in the midbody region in anaphase, characterised using a monoclonal antibody

1990 • 37 citations

ATPases in Mitotic Spindles

1984 • 30 citations

Identification and characterizaton of a protein associated with the stembody using autoimmune sera from patients with systemic sclerosis

1987 • 29 citations

An antigen in metaphase chromatin and the midbody of mammalian cells binds to scleroderma sera.

1987 • 19 citations

Identification of a 52-kD calmodulin-binding protein associated with the mitotic spindle apparatus in mammalian cells.

1986 • 15 citations

Isolation of a 50 kDa polypeptide from the detergent-resistant unfertilized sea urchin egg cytomatrix and evidence for its change in organization during mitosis.

1988 • 8 citations