ATPases in Mitotic Spindles

Molecules and Cell Movement

1977 • 767 citations

Cell Motility by Labile Association of Molecules

1967 • 767 citations

Dynein: A Protein with Adenosine Triphosphatase Activity from Cilia

1965 • 579 citations

Opposite end assembly and disassembly of microtubules at steady state in vitro

1978 • 567 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

Fluorescent antibody localization of myosin in the cytoplasm, cleavage furrow, and mitotic spindle of human cells.

1976 • 539 citations

Control of microtubule assembly-disassembly by calcium-dependent regulator protein.

1978 • 493 citations

The effect of myosin antibody on the division of starfish blastomeres

1977 • 445 citations

Model for Mitosis

1969 • 370 citations

Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2.

1982 • 334 citations

Cell division and the mitotic spindle.

1981 • 323 citations

STUDIES ON THE PROTEIN COMPONENTS OF CILIA FROM TETRAHYMENA PYRIFORMIS

1963 • 280 citations

Microtubule treadmills—possible molecular machinery

1981 • 279 citations

Calcium-dependent regulator protein: Localization in mitotic apparatus of eukaryotic cells

1978 • 252 citations

A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2)

1981 • 243 citations

Mitotic mechanism based on intrinsic microtubule behaviour

1978 • 232 citations

Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo.

1980 • 232 citations

The Isolation and Biochemical Characterization of the Mitotic Apparatus of Dividing Cells

1952 • 225 citations

The control of cell division; a review. I. General mechanisms.

1957 • 223 citations

Structural polarity of kinetochore microtubules in PtK1 cells.

1981 • 218 citations

Rethinking mitosis

1982 • 195 citations

Studies on the in vivo sensitivity of spindle microtubules to calcium ions and evidence for a vesicular calcium-sequestering system.

1981 • 193 citations

THE ENERGY RELATIONS OF MITOTIC ACTIVITY

1952 • 186 citations

Mechanisms and control of cell division

1977 • 178 citations

Calcium-labile mitotic spindles isolated from sea urchin eggs (Lytechinus variegatus).

1980 • 158 citations

A dynein‐like protein associated with neurotubules

1974 • 154 citations

Chromosome movement in lysed mitotic cells is inhibited by vanadate.

1978 • 154 citations

Nuclear Division in the Fungi

1979 • 154 citations

Contractile proteins

1975 • 153 citations

A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence.

1977 • 150 citations

Isolation of mitotic apparatus containing vesicles with calcium sequestration activity

1980 • 148 citations

Dynein binds to and crossbridges cytoplasmic microtubules.

1979 • 146 citations

Detection of the membrane-calcium distribution during mitosis in Haemanthus endosperm with chlorotetracycline.

1980 • 138 citations

INTERMICROTUBULE BRIDGES IN MITOTIC SPINDLE APPARATUS

1970 • 135 citations

Presence of actin during chromosomal movement.

1975 • 134 citations

A dynein‐like protein from brain

1974 • 130 citations

Structure of the dynein-1 outer arm in sea urchin sperm flagella. I. Analysis by separation of subunits.

1982 • 129 citations

Primary structural differences among tubulin subunits from flagella, cilia, and the cytoplasm

1978 • 127 citations

Decoration of spindle microtubules with Dynein: evidence for uniform polarity.

1981 • 126 citations

Evidence that myosin does not contribute to force production in chromosome movement.

1982 • 125 citations

Simultaneous localization of myosin and tubulin in human tissue culture cells by double antibody staining

1978 • 123 citations

Inner arm dyneins from flagella of chlamydomonas reinhardtii

1981 • 118 citations

Spindle microtubules and their mechanical associations after micromanipulation in anaphase.

1982 • 116 citations

Comparison of purified anti-actin and fluorescent-heavy meromyosin staining patterns in dividing cells.

1979 • 115 citations

erythro-9-[3-(2-Hydroxynonyl)]adenine is an inhibitor of sperm motility that blocks dynein ATPase and protein carboxylmethylase activities.

1981 • 115 citations

THE EFFECTS OF CARBON MONOXIDE INHIBITION ON ATP LEVEL AND THE RATE OF MITOSIS IN THE SEA URCHIN EGG

1963 • 114 citations

Traction force on a kinetochore at metaphase acts as a linear function of kinetochore fiber length

1982 • 110 citations

Analysis of actin and microfilament-associated proteins in the mitotic spindle and cleavage furrow of PtK2 cells by immunofluorescence microscopy

1979 • 110 citations

Calmodulin and the regulation of the actin—myosin interaction in smooth muscle and nonmuscle cells

1982 • 108 citations

CHROMOSOME VELOCITY DURING MITOSIS AS A FUNCTION OF CHROMOSOME SIZE AND POSITION

1965 • 106 citations

Calmodulin confers calcium sensitivity on ciliary dynein ATPase.

1980 • 105 citations

Dynein-like Mg2+-ATPase in mitotic spindles isolated from sea urchin embryos (Strongylocentrotus droebachiensis).

1980 • 105 citations

SPINDLE MICROTUBULES: THERMODYNAMICS OF IN VIVO ASSEMBLY AND ROLE IN CHROMOSOME MOVEMENT*

1975 • 105 citations

Nucleotide requirements for anaphase chromosome movements in permeabilized mitotic cells: Anaphase B but not anaphase a requires ATP

1982 • 103 citations

ARMS AND BRIDGES ON MICROTUBULES IN THE MITOTIC APPARATUS

1969 • 103 citations

Polarity of spindle microtubules in Haemanthus endosperm.

1982 • 102 citations

Regulation of the microtubule steady state in vitro by ATP

1979 • 99 citations

Study of the mechanism of vanadate inhibition of the dynein cross-bridge cycle in sea urchin sperm flagella

1979 • 97 citations

The identification of a dynein ATPase in unfertilized sea urchin eggs

1980 • 91 citations

A Ca-activated ATPase in the mitotic apparatus of the sea urchin egg (isolated by a new method)

1972 • 90 citations

Studies on ATPase activity of sea urchin eggs and the isolated mitotic apparatus

1968 • 90 citations

Microtubule assembly in living cells after release from nocodazole block: The effects of metabolic inhibitors, taxol and PH

1981 • 89 citations

Ionic changes in the mitotic apparatus at the metaphase/anaphase transition.

1983 • 88 citations

Motility of Cilia and the Mechanism of Mitosis

1959 • 88 citations

Ca2+-activated ATPase during the cell cycle of the sea urchin Strongylocentrotus purpuratus

1972 • 86 citations

Polypeptide subunits of dynein 1 from sea urchin sperm flagella

1979 • 84 citations

Functional implications of cold-stable microtubules in kinetochore fibers of insect spermatocytes during anaphase.

1980 • 83 citations

ULTRASTRUCTURE AND BIREFRINGENCE OF THE ISOLATED MITOTIC APPARATUS OF MARINE EGGS

1967 • 81 citations

THE MITOTIC APPARATUS

1962 • 81 citations

Actin localization in fixed dividing cells stained with fluorescent heavy meromyosin

1978 • 76 citations

A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells.

1981 • 73 citations

Dynein: The Mechanochemical Coupling Adenosine Triphosphatase of Microtubule-Based Sliding Filament Mechanisms

1980 • 72 citations

Characterization of rat brain crude extract microtubule assembly: correlation of cold stability with the phosphorylation state of a microtubule-associated 64K protein

1981 • 70 citations

Immunofluorescent localization of cyclic nucleotide-dependent protein kinases on the mitotic apparatus of cultured cells.

1980 • 70 citations

Micromanipulation studies of chromosome movement. I. Chromosome-spindle attachment and the mechanical properties of chromosomal spindle fibers.

1979 • 68 citations

Biochemistry of the Mitotic Spindle

1979 • 68 citations

Die bedeutung des adenosintriphosphat für die zell-und kernteilungsbewegungen in der anaphase

1954 • 66 citations

Differential staining of actin in metaphase spindles with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin and fluorescent DNase: is actin involved in chromosomal movement?

1981 • 62 citations

Dynein ATPase is inhibited selectively in vitro by erythro-9-[3-2-(hydroxynonyl)]adenine

1982 • 61 citations

Cytoplasmic Dynein of the Sea Urchin Egg.1 II. Purification, Characterization and Interactions with Microtubules and Ca-Calmodulin

1983 • 61 citations

INDUCTION OF CHROMOSOME MOTION IN THE GLYCEROL-ISOLATED MITOTIC APPARATUS: NUCLEOTIDE SPECIFICITY AND EFFECTS OF ANTIDYNEIN AND MYOSIN SERA ON THE MOTION*

1976 • 59 citations

Studies on kinetochore function in mitosis. I. The effects of colchicine and cytochalasin on mitosis in the diatom Hantzschia amphioxys.

1982 • 57 citations

Structure of the dynein-1 outer arm in sea urchin sperm flagella. II. Analysis by proteolytic cleavage.

1982 • 56 citations

Preparation of antiserum against a tryptic fragment (fragment A) of dynein and an immunological approach to the subunit composition of dynein

1975 • 56 citations

High molecular weight MAPs are part of the mitotic spindle

1978 • 55 citations

ADENOSINE TRIPHOSPHATASE IN THE MITOTIC APPARATUS

1961 • 54 citations

LOCALIZATION OF DYNEIN IN SEA URCHIN EGGS DURING CLEAVAGE*

1976 • 51 citations

The Isolated Mitotic Apparatus and Chromosome Motion

1978 • 48 citations

The ATPase activity of the mitotic apparatus of the sea urchin egg*1, *2

1963 • 45 citations

Calcium Sensitivity of Sea Urchin Tubulin in In Vitro Assembly and the Effects of Calcium-Dependent Regulator (CDR) Proteins Isolated from Sea Urchin Eggs and Porcine Brains1

1980 • 42 citations

Adenosine triphosphatase activity of bovine brain microtubule protein.

1980 • 41 citations

Arrest of mitosis in roots by oxygen-lack or cyanide

1961 • 40 citations

Calmodulin and cell functions

1980 • 40 citations

Dependence of mitosis and respiration in roots upon oxygen tension

1961 • 39 citations

Absence of microtubule sliding and an analysis of spindle formation and elongation in isolated mitotic spindles from the yeast Saccharomyces cerevisiae.

1982 • 37 citations

The mitotic apparatus of a giant ameba

1969 • 35 citations

Strongylocentrotus purpuratus spindle tubulin. II. Characteristics of its sensitivity to Ca++ and the effects of calmodulin isolated from bovine brain and S. purpuratus eggs.

1982 • 34 citations

The Presence of an Adenosine-5'-Triphosphatase Dependent on 6S Tubulin and Calcium Ions in Rat Brain Microtubules

1979 • 34 citations

THE MITOTIC APPARATUS ISOLATED IN GLYCEROL‐CONTAINING MEDIUM

1974 • 34 citations

THE GLYCEROL-ISOLATED MITOTIC APPARATUS: A RESPONSE TO PORCINE BRAIN TUBULIN AND INDUCTION OF CHROMOSOME MOTION

1975 • 31 citations

<b>LOCALIZATION OF FLUORESCENTLY LABELED CALMODULIN IN LIVING SEA URCHIN EGGS DURING EARLY </b><b>DEVELOPMENT </b>

1980 • 31 citations

Identity and origin of the ATPase activity associated with neuronal microtubules. II. Identification of a 50,000-dalton polypeptide with ATPase activity similar to F-1 ATPase from mitochondria.

1983 • 28 citations

Immunofluorescence and inhibitor studies on creatine kinase and mitosis

1982 • 26 citations

Studies on kinetochore function in mitosis. II. The effects of metabolic inhibitors on mitosis and cytokinesis in the diatom Hantzschia amphioxys.

1982 • 26 citations

Effects of antibodies against dynein and tubulin on the stiffness of flagellar axonemes.

1981 • 26 citations

Identity and Origin of the ATPase activity associated with neuronal microtubules. I. The ATPase activity is associated with membrane vesicles.

1983 • 25 citations

Further evidence that a Ca-activated ATPase is connected with the cell cycle

1972 • 25 citations

NON-IDENTICAL MECHANISMS OF MITOTIC ARREST BY RESPIRATORY INHIBITORS IN PEA ROOT TIPS AND SEA URCHIN EGGS

1963 • 25 citations

Ca2+-stimulated ATpase during the early development of parthenogenetically activated eggs of the sea urchin Paracentrotus lividus

1973 • 25 citations

Polarity of dynein-microtubule interactions in vitro: cross-bridging between parallel and antiparallel microtubules.

1981 • 24 citations

Synthesis and activation of mitotic Ca2+-adenosinetriphosphatase during the cell cycle of mouse mastocytoma cells.

1977 • 24 citations

The effect of dinitrophenol and other phosphorylation uncouplers on the birefringence of the mitotic apparatus of marine eggs

1969 • 23 citations

A probe for flagellar dynein in the mammalian mitotic apparatus

1981 • 21 citations

Microtubule Polarity and Interaction in Mitotic Spindle Function

1981 • 20 citations

The isolation and preliminary electrophoretic analyses of the mitotic spindle from cultured mammalian cells

1977 • 19 citations

The Structure and Role of Membranes in the Mitotic Apparatus

1981 • 18 citations

Introduction: Dynein ATPases

1982 • 17 citations

DNA replication in Physarum polycephalum: electron microscopic analysis of patterns of DNA replication in the presence of cycloheximide.

1982 • 16 citations

CYTOCHEMICAL LOCALIZATION OF ADENOSINE TRIPHOSPHATASE IN THE MITOTIC APPARATUS OF HELA AND SARCOMA 180 TISSUE CULTURE CELLS

1964 • 16 citations

Analysis of chromosome movement in crane fly spermatocytes by ultraviolet microbeam irradiation of individual chromosomal spindle fibres. II. Action spectra for stopping chromosome movement and for blocking ciliary beating and myofibril contractions

1981 • 16 citations

Invited review: The role of nucleotide triphosphate in actin and tubulin assembly and function

1981 • 13 citations

NH3-treatment of unfertilized sea urchin eggs turns on the Ca2+-ATPase cycle

1976 • 10 citations

Mitosis and Cytokinesis

2009 • 8 citations

Presence of two distinct adenosine triphosphatase activities in bovine brain microtubules

1982 • 7 citations

ULTRASTRUCTURAL LOCALIZATION OF ATPASES AND 5′-NUCLEOTIDASE ACTIVITY IN CHINESE HAMSTER MITOTIC CELLS

1979 • 7 citations

ARE THE SEA URCHIN MITOTIC Ca²⁺‐ATPASE AND Ca²⁺‐SEQUESTERING ACTIVITIES AFFECTE BY CALMODULIN?

1980 • 6 citations

ATP-ASE STAINING OF SEA URCHIN EGGS DURING THE FIRST CLEAVAGE1)

1964 • 5 citations

The mitotic Ca-adenosine triphosphatase in proliferating tissue of Vicia faba

1980 • 4 citations

Cyclic fluctuations of the mitotic Ca-ATPase during the cell cycle of the myxomycete Physarum polycephalum

1980 • 4 citations