Transition from normal to epileptiform activity in kindled rat hippocampal slices

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices

1987 • 642 citations

Excitatory synaptic interactions between CA3 neurones in the guinea‐pig hippocampus.

1986 • 503 citations

Frequency-dependent involvement of NMDA receptors in the hippocampus: a novel synaptic mechanism

1986 • 416 citations

Afterpotential generation in hippocampal pyramidal cells.

1981 • 401 citations

Electrophysiology of Epilepsy

1985 • 392 citations

Activity-dependent disinhibition. I. Repetitive stimulation reduces IPSP driving force and conductance in the hippocampus in vitro

1989 • 328 citations

The role of protein kinase C in long-term potentiation: a testable model

1989 • 278 citations

Optical imaging of calcium accumulation in hippocampal pyramidal cells during synaptic activation

1989 • 265 citations

Latent synaptic pathways revealed after tetanic stimulation in the hippocampus

1987 • 220 citations

Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices

1990 • 220 citations

Abnormal neuronal excitability in hippocampal slices from kindled rats

1985 • 206 citations

EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs

1989 • 153 citations

Seizure-like events in brain slices: suppression by interictal activity

1987 • 137 citations

The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice

1987 • 136 citations

EPSPs in rat neocortical neurons in vitro. I. Electrophysiological evidence for two distinct EPSPs

1989 • 132 citations

Interictal EEG spikes correlate with decreased, rather than increased, epileptogenicity in amygdaloid kindled rats

1980 • 130 citations

Induction of epileptiform activity in hippocampal slices by trains of electrical stimuli

1985 • 127 citations

Electrophysiological and optical changes in slices of rat hippocampus during spreading depression

1983 • 122 citations

Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex

1989 • 103 citations

Influences of sinusoidal electric fields on excitability in the rat hippocampal slice

1984 • 69 citations

Increased ectopic action potential generation accompanies epileptogenesis in vitro

1990 • 40 citations

Cerebellar Stimulation in Alumina‐Gel Monkey Model: Inverse Relationship Between Clinical Seizures and EEG Interictal Bursts

1979 • 38 citations

Control of epileptiform burst rate by CA3 hippocampal cell afterhyperpolarizations in vitro

1989 • 38 citations

Mechanisms of epileptogenesis. The transition to seizure

1989 • 27 citations

Spontaneous interictal spiking in the awake kindled rat

1979 • 27 citations

Mechanisms of epileptogenesis in brain-slice model systems.

1983 • 24 citations

Epileptogenic mechanisms as revealed by studies of the hippocampal slice

1984 • 21 citations

Induction of delayed synchronized bursts in hippocampal slices by weak sine-wave stimulation; role of the NMDA receptor

1989 • 6 citations

Mechanisms of Kindling: A Speculative Hypothesis

1988 • 5 citations