Mechanisms of Kindling: A Speculative Hypothesis

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Topographic organization of the projections from the entorhinal area to the hippocampal formation of the rat

1976 • 872 citations

Development of Epileptic Seizures through Brain Stimulation at Low Intensity

1967 • 854 citations

Substantia Nigra: Site of Anticonvulsant Activity Mediated by γ-Aminobutyric Acid

1982 • 601 citations

Long-term potentiation phenomena in the rat limbic forebrain

1983 • 562 citations

Long-term potentiation of the perforant path-granule cell synapse in the rat hippocampus

1975 • 501 citations

Kindling

1978 • 482 citations

Crossed connections of the substantia nigra in the rat

1982 • 431 citations

Involvement of N‐methyl‐D‐aspartate receptors in epileptiform bursting in the rat hippocampal slice.

1986 • 365 citations

The effects of kindling on GABA-Mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression

1983 • 333 citations

Generalized convulsive seizures induced by daily electrical stimulation of the amygdala in cats

1974 • 322 citations

An autoradiographic study of the efferent connections of the entorhinal cortex in the rat

1981 • 305 citations

Evidence implicating substantia nigra in regulation of kindled seizure threshold

1984 • 301 citations

Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents

1976 • 300 citations

Immunocytochemical localization of glutamate decarboxylase in rat substantia nigra

1976 • 272 citations

Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition

1987 • 272 citations

Neuronal transmission through hippocampal pathways dependent on behavior

1978 • 264 citations

Anatomical correlates of electrical and behavioral events related to amygdaloid kindling

1978 • 247 citations

Does the Engram of Kindling Model the Engram of Normal Long Term Memory?

1975 • 220 citations

Transfer, interference and spontaneous recovery of convulsions kindled from the rat amygdala

1973 • 207 citations

Excitatory Synapses on Hippocampal Apical Dendrites Activated by Entorhinal Stimulation

1966 • 207 citations

Abnormal neuronal excitability in hippocampal slices from kindled rats

1985 • 206 citations

Role of forebrain catecholamines in amygdaloid kindling

1980 • 187 citations

The kindling model of epilepsy: a critical review.

1985 • 186 citations

Rates of motor seizure development in rats subjected to electrical brain stimulation: strain and inter-stimulation interval effects

1973 • 180 citations

Effects of muscimol and picrotoxin on single unit activity of substantia nigra neurons

1980 • 165 citations

Electrode placement and kindling-induced experiemental epilepsy

1978 • 141 citations

Cellular and synaptic properties of amygdala-kindled pyriform cortex in vitro

1986 • 138 citations

Spontaneous recurrent seizure state induced by daily electric amygdaloid stimulation in Senegalese baboons ( Papio papio )

1976 • 132 citations

Alterations of inhibitory processes in the dentate gyrus following kindling-induced epilepsy

1985 • 125 citations

The pharmacology of seizures induced by sensitization with low intensity brain stimulation

1973 • 124 citations

The output organization of the substantia nigra in primate as revealed by a retrograde double labeling method

1983 • 116 citations

Quantitative analysis of synaptic potentiation during kindling of the perforant path

1986 • 115 citations

Intradentate colchicine retards the development of amygdala kindling

1982 • 114 citations

Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats

1986 • 93 citations

Hippocampal slices of kindled rats reveal calcium involvement in epileptogenesis

1985 • 89 citations

Knife cuts of entorhinal cortex: effects on development of amygdaloid kindling and seizure-induced decrease of muscarinic cholinergic receptors

1985 • 83 citations

Sprouting fibers gain access to circuitry transsynaptically altered by kindling

1979 • 79 citations

Behavioral analysis of amygdaloid kindling in beagle dogs and the effects of clonazepam, diazepam, phenobarbital, diphenylhydantoin, and flunarizine on seizure manifestation

1979 • 79 citations

Chemical kindling by muscarinic amygdaloid stimulation in the rat

1983 • 75 citations

Effects of γ-acetylenic GABA and γ-vinyl GABA on metrazol-activated, and kindled seizures

1979 • 69 citations

Evidence implicating dentate granule cells in development of entorhinal kindling

1986 • 68 citations

A pharmacological study in the kindling model of epilepsy

1984 • 67 citations

Progressive changes of behavioral and electroencephalographic responses to daily amygdaloid stimulations in rabbits

1974 • 67 citations

Depletion of noradrenaline fails to affect kindled seizures

1984 • 65 citations

Electrically induced seizure activity in the hippocampus: Time course for postseizure inhibition of subsequent kindled seizures

1978 • 60 citations

Kindling rates in inbred mice: an analog to learning?

1976 • 55 citations

Kindling in the frog: Development of spontaneous epileptiform activity

1976 • 50 citations

Aspartate-induced changes in extracellular free calcium in ‘in vitro’ hippocampal slices of rats

1982 • 50 citations

Kindling with low-frequency stimulation: Generality, transfer, and recruiting effects

1981 • 43 citations

Development and reduction of synaptic potentiation induced by perforant path kindling

1982 • 35 citations

Kindling antagonism: Interactions of dorsal and ventral entorhinal cortex with the septum during concurrent kindling

1982 • 21 citations

Muscarinic cholinergic regulation of epileptic spiking in kindling

1979 • 18 citations