bozozokdirectly repressesbmp2btranscription and mediates the earliest dorsoventral asymmetry ofbmp2bexpression in zebrafish

Stages of embryonic development of the zebrafish

1995 • 11,263 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

1999 • 823 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

A β-catenin/XTcf-3 complex binds to thesiamois promoter to regulate dorsal axis specification in Xenopus

1997 • 527 citations

Expression cloning of Siamois, a xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis

1995 • 521 citations

The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning

1997 • 518 citations

β-catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos

1996 • 516 citations

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin

1995 • 436 citations

Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen

1989 • 432 citations

Ventral and Lateral Regions of the Zebrafish Gastrula, Including the Neural Crest Progenitors, Are Established by abmp2b/swirlPathway of Genes

1998 • 424 citations

Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes

1996 • 408 citations

Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus

1997 • 351 citations

Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

1997 • 350 citations

Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP‐2 and BMP‐4

1995 • 344 citations

Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development

1999 • 338 citations

Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus

1997 • 332 citations

Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish

1996 • 323 citations

Functional domains of the Drosophila Engrailed protein.

1993 • 280 citations

A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo

1996 • 280 citations

The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controling dorsoventral patterning of Xenopus mesoderm

1996 • 275 citations

Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation

2000 • 269 citations

Reporter constructs with low background activity utilizing the cat gene

1992 • 240 citations

The Xenopus homeobox gene Twin mediates Wnt induction of Goosecoid in establishment of Spemann’s organizer

1997 • 220 citations

Conservation of BMP signaling in zebrafish mesoderm patterning

1997 • 210 citations

Differential Regulation ofchordinExpression Domains in Mutant Zebrafish

1997 • 210 citations

Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo

2000 • 202 citations

The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures

1999 • 196 citations

The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo

1999 • 193 citations

Zebrafish Dkk1 Functions in Forebrain Specification and Axial Mesendoderm Formation

2000 • 188 citations

Centrosome duplication continues in cycloheximide-treated Xenopus blastulae in the absence of a detectable cell cycle.

1990 • 176 citations

The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of Nodal signaling required for organizer formation

2000 • 155 citations

A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene

1999 • 139 citations

A novel homeobox gene, dharma, can induce the organizer in a non-cell-autonomous manner

1998 • 131 citations

Cloning and expression of three members of the zebrafish Bmp family: Bmp2a, Bmp2b and Bmp4

1997 • 124 citations

The homeobox genesvoxandventare redundant repressors of dorsal fates in zebrafish

2001 • 117 citations

Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish

2000 • 114 citations

The homeobox gene bozozok promotes anterior neuroectoderm formation in zebrafish through negative regulation of BMP2/4 and Wnt pathways

2000 • 105 citations

Patterning the Early Zebrafish by the Opposing Actions of bozozok and vox/vent

2000 • 102 citations

Regulation of dharma/bozozok by the Wnt Pathway

2001 • 87 citations

The nieuwkoid/dharma Homeobox Gene Is Essential for bmp2b Repression in the Zebrafish Pregastrula

1999 • 82 citations

The nieuwkoid gene characterizes and mediates a Nieuwkoop-center-like activity in the zebrafish

1998 • 80 citations

Transcriptional regulation of Xvent homeobox genes

1999 • 79 citations

Maternally Supplied Smad5 Is Required for Ventral Specification in Zebrafish Embryos Prior to Zygotic Bmp Signaling

2002 • 75 citations

DNA-Binding Specificity and Embryological Function of Xom (Xvent-2)

1999 • 75 citations

A novel repressor-type homeobox gene, ved, is involved in dharma/bozozok-mediated dorsal organizer formation in zebrafish

2002 • 70 citations

The homeobox gene, Xanf-1, can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo

1999 • 69 citations

Antagonistic role of vega1 and bozozok/dharma homeobox genes in organizer formation

2000 • 68 citations

Xvent-1 mediates BMP-4-induced suppression of the dorsal-lip-specific early response gene XFD-1' in Xenopus embryos

1998 • 53 citations

The role of the homeodomain protein Bozozok in zebrafish axis formation.

2001 • 51 citations

Regulation of Dorsal Gene Expression in Xenopus by the Ventralizing Homeodomain Gene Vox

1999 • 50 citations

Antimorphic goosecoids

1998 • 49 citations

Functional interaction ofvega2 andgoosecoid homeobox genes in zebrafish

2000 • 49 citations

Two-color detection of mRNA transcript localizations in fish and fly embryos using alkaline phosphatase and β-galactosidase conjugated antibodies

1999 • 39 citations