Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

Kainic acid as a tool in neurobiology

1978 • 1,314 citations

THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS

1960 • 853 citations

2-Amino-4-Phosphonobutyric Acid: A New Pharmacological Tool for Retina Research

1981 • 821 citations

Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS

1981 • 728 citations

2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation

1981 • 468 citations

THE EFFECTS OF A SERIES OF ω‐PHOSPHONIC α‐CARBOXYLIC AMINO ACIDS ON ELECTRICALLY EVOKED AND EXCITANT AMINO ACID‐INDUCED RESPONSES IN ISOLATED SPINAL CORD PREPARATIONS

1982 • 463 citations

The pharmacology of amino acids related to gamma-aminobutyric acid.

1965 • 333 citations

New class of glutamate agonist structurally related to ibotenic acid

1980 • 309 citations

Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex

1981 • 307 citations

Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord

1982 • 302 citations

Glutamate transmitter in the central nervous system

1982 • 259 citations

Glutamate as transmitter of hippocampal perforant path

1977 • 227 citations

CHANGES IN AMINO ACID CONCENTRATIONS ASSOCIATED WITH LOSS OF SPINAL INTERNEURONS *

1967 • 211 citations

Selective antagonism of amino acid‐induced and synaptic excitation in the cat spinal cord.

1979 • 195 citations

Sulfite oxidase deficiency: Studies of a patient with mental retardation, dislocated ocular lenses, and abnormal urinary excretion of S-sulfo-l-cysteine, sulfite, and thiosulfate

1967 • 165 citations

ANTAGONISM OF EXCITATORY AMINO ACID‐INDUCED RESPONSES AND OF SYNAPTIC EXCITATION IN THE ISOLATED SPINAL CORD OF THE FROG

1979 • 152 citations

Cysteine-S-Sulfate: Brain Damaging Metabolite in Sulfite Oxidase Deficiency1

1975 • 137 citations

D-α-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones

1977 • 135 citations

Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones

1981 • 132 citations

Differentiation of kainate and quisqualate receptors in the cat spinal cord by selective antagonism with γ-D(and L)-glutamylglycine

1981 • 115 citations

Neurotransmitters, seizures, and epilepsy

1981 • 113 citations

The effect of acidic amino acid antagonists on synaptic transmission in the hippocampal formation in vitro

1979 • 95 citations

Distinct pharmacological properties of excitatory amino acid receptors in the rat striatum: study by Na+ efflux assay.

1981 • 91 citations

2-Amino-4-phosphonobutyric acid as a glutamate antagonist on locust muscle

1976 • 90 citations

Antagonism of Excitatory Amino Acid-Induced and Synaptic Excitation of Spinal Neurones by cis-2,3-Piperidine Dicarboxylate

1981 • 83 citations

Pharmacological antagonists of excitant amino acid action

1981 • 77 citations

D-α-Aminoadipate, α,ε-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synaptic excitation of mammalian spinal neurones in vivo

1978 • 71 citations

The action of D-α-aminoadipate on excitatory amino acid receptors of rat thalamic neurones

1978 • 56 citations

Dipeptide Antagonists of Amino Acid‐Induced and Synaptic Excitation in the Frog Spinal Cord

1980 • 56 citations

Aspartate and other inhibitors of excitatory synaptic transmission in crayfish muscle

1977 • 44 citations

The isomers of 2-amino-5-phosphonovalerate as excitatory amino acid antagonists—A reappraisal

1982 • 18 citations

2-Amino-7-phosphonoheptanoic acid as an amino acid antagonist

1982 • 15 citations