Bilirubin kinetics in intact rats and isolated perfused liver. Evidence for hepatic deconjugation of bilirubin glucuronides.

Gluconeogenesis in the perfused rat liver

1966 • 726 citations

Data for Biochemical Research.

1960 • 411 citations

Hepatic organic anion uptake in the rat.

1975 • 250 citations

A simple and inexpensive membrane “lung” for small organ perfusion

1974 • 236 citations

Studies of bilirubin kinetics in normal adults

1969 • 235 citations

The ready isomerization of bilirubin IX-α in aqueous solution

1972 • 232 citations

METABOLISM AND DISPOSITION OF C14-BILIRUBIN IN CONGENITAL NONHEMOLYTIC JAUNDICE*

1963 • 221 citations

THE PREPARATION OF CRYSTALLINE BILIRUBIN-C14*

1961 • 208 citations

Catabolism of heme in vivo: comparison of the simultaneous production of bilirubin and carbon monoxide

1970 • 186 citations

Analysis of bilirubin and bilirubin mono- and di-conjugates. Determination of their relative amounts in biological samples

1980 • 181 citations

Commercial bilirubin: A trinity of isomers

1971 • 162 citations

Constitutional hepatic dysfunction (Gilbert's syndrome)

1970 • 159 citations

Quantitative separation and determination of bilirubin and conjugated bilirubin in human serum

1962 • 150 citations

Perfusion techniques in biochemistry

1973 • 145 citations

INTESTINAL ABSORPTION OF BILE PIGMENTS. I. THE ENTEROHEPATIC CIRCULATION OF BILIRUBIN IN THE RAT*

1963 • 142 citations

THE PROTEIN-BINDING OF C14-BILIRUBIN IN HUMAN AND MURINE SERUM*

1963 • 140 citations

Bilirubin conjugates in bile of man and rat in the normal state and in liver disease

1972 • 130 citations

Intestinal Absorption of Bile Pigments

1963 • 130 citations

Measurement of bilirubin and its monoconjugates and diconjugates in human serum by alkaline methanolysis and high-performance liquid chromatography.

1980 • 127 citations

The fate of bilirubin-IXα glucuronide in cholestasis and during storage in vitro. Intramolecular rearrangement to positional isomers of glucuronic acid

1978 • 123 citations

DEFECTS IN HEPATIC TRANSPORT OF BILIRUBIN IN CONGENITAL HYPERBILIRUBINAEMIA: AN ANALYSIS OF PLASMA BILIRUBIN DISAPPEARANCE CURVES.

1964 • 118 citations

Interaction of Bilirubin with Albumin

1965 • 106 citations

Purification and Properties of Human Liver β-Glucuronidase

1965 • 76 citations

Hepatic Accumulation and Intracellular Binding of Conjugated Bilirubin

1978 • 74 citations

Bilirubin diglucuronide synthesis by a UDP-glucuronic acid-dependent enzyme system in rat liver microsomes.

1979 • 73 citations

Comparison of the biliary excretion of the four isomers of bilirubin-IX in Wistar and homozygous Gunn rats

1977 • 65 citations

Use of Kinetic Analysis and Mathematical Modeling in the Study of Metabolic Pathways in Vivo

1979 • 64 citations

Bilirubin Turnover Studies in Normal and Pathologic States Using Bilirubin-^14C

1968 • 62 citations

Mathematical Techniques For Physiology and Medicine

1972 • 61 citations

Studies on the biosynthesis production of bilirubin-C14: an improved method utilizing delta-aminolevulinic acid-4-C14 in dogs.

1966 • 56 citations

The isolation and further characterization of the bilirubin tetrapyrroles in bile-containing human duodenal juice and dog gall-bladder bile

1977 • 54 citations

An expanded model of bilirubin kinetics: Effect of feeding, fasting, and phenobarbital in Gilbert's syndrome

1976 • 45 citations

Effect of Phenobarbitone on Plasma [14C]Bilirubin Clearance in Patients with Unconjugated Hyperbilirubinaemia

1974 • 44 citations

Bilirubin production as a measure of red cell life span.

1972 • 41 citations

Interpretation of plasma bilirubin levels based on studies with radioactive bilirubin.

1971 • 38 citations

Quantitative studies of the delivery of hepatic-synthesized bilirubin to plasma utilizing δ-aminolevulinic acid-4-14C and bilirubin-3H in man

1972 • 36 citations

The identification of monoconjugates of bilirubin in bile as amide derivatives

1971 • 36 citations

DOES DECONJUGATION OF BILIRUBIN GLUCURONIDE OCCUR IN OBSTRUCTIVE JAUNDICE ?

1968 • 34 citations

Mechanism of Bilirubin Diglucuronide Formation in Intact Rats

1980 • 32 citations

Bilirubin Metabolism in Congenital Nonhemolytic Jaundice

1971 • 27 citations

Bile pigment excretion: a comparison of the biliary excretion of bilirubin and bilirubin derivatives.

1966 • 24 citations

On the autoxidation of bilirubin

1976 • 24 citations

DECONJUGATION OF BILIRUBIN GLUCURONIDE BY THE LIVER

1968 • 20 citations

Localization of Bilirubin Pools in the Non-Jaundiced Rat, with a Note on Bilirubin Dynamics in Normal Human Adults and in Gilbert's Syndrome

1972 • 20 citations

Studies of the kinetics of purified conjugated bilirubin-3H in the rat.

1978 • 19 citations

Interpretation of plasma bilirubin levels based on studies with radioactive bilirubin

1971 • 16 citations

Inaccuracies in measurement of conjugated and unconjugated bilirubin in bile with ethyl anthranilate diazo and solvent-partition methods

1978 • 15 citations

Studies on the Kinetics of Unconjugated [14C]Bilirubin Metabolism in Normal Subjects and Patients with Compensated Cirrhosis

1977 • 14 citations

The mechanism of removal of rose bengal from the plasma of the rat. Determined by autoradiography and radioassay.

1959 • 10 citations

Efflux of Bilirubin into Plasma following Hepatic Degradation of Exogenous Heme

1980 • 10 citations

Comparison of the Weber-Schalm Method with the Ducci-Watson Modification of the Malloy-Evelyn Method for Serum Bilirubin Determination

1970 • 8 citations

The Effect of Repeated Phlebotomy on Bilirubin Turnover, Bilirubin Clearance and Unconjugated Hyperbilirubinaemia in the Crigler—Najjar Syndrome and the Jaundiced Gunn Rat: Application of Computers to Experimental Design

1976 • 6 citations

A compartmental model for bilirubin kinetics in isolated perfused rat liver

1976 • 6 citations