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Effect of Phenobarbitone on Plasma [14C]Bilirubin Clearance in Patients with Unconjugated Hyperbilirubinaemia

Data up to Jan 2025

Published1974
Citations44
References34

Total Citations Per Year

Abstract

References (34)

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

1969 • 589 citations

Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency

1969 • 332 citations

Hepatic Bilirubin UDP-Glucuronyl Transferase Activity in Liver Disease and Gilbert's Syndrome

1969 • 274 citations

Enhancement of Glucuronide-Conjugating Capacity in a Hyperbilirubinemic Infant Due to Apparent Enzyme Induction by Phenobarbital

1966 • 260 citations

METABOLISM AND DISPOSITION OF C14-BILIRUBIN IN CONGENITAL NONHEMOLYTIC JAUNDICE*

1963 • 221 citations

Mechanism of phenobarbital-induced hypercholeresis in the rat

1970 • 209 citations

THE PREPARATION OF CRYSTALLINE BILIRUBIN-C14*

1961 • 208 citations

Idiopathic Unconjugated Hyperbilirubinemia (Gilbert's Syndrome)

1967 • 170 citations

Constitutional hepatic dysfunction (Gilbert's syndrome)

1970 • 159 citations

Determination of bilirubin UDP-glucuronyl transferase activity in needle-biopsy specimens of human liver

1970 • 155 citations

Quantitative separation and determination of bilirubin and conjugated bilirubin in human serum

1962 • 150 citations

PLASMA BILIRUBIN DETERMINATION IN THE NEWBORN INFANT

1965 • 135 citations

Heterogeneity of bile pigment conjugates as revealed by chromatography of their anthranilate azopigments

1970 • 123 citations

Barbiturate Enhancement of Bilirubin Conjugation and Excretion in Young and Adult Animals[35]

1968 • 120 citations

Constitutional hepatic dysfunction (Gilbert's disease).

1968 • 120 citations

DEFECTS IN HEPATIC TRANSPORT OF BILIRUBIN IN CONGENITAL HYPERBILIRUBINAEMIA: AN ANALYSIS OF PLASMA BILIRUBIN DISAPPEARANCE CURVES.

1964 • 118 citations

The Effects of Phenobarbital on Bile Salts and Bilirubin in Patients with Intrahepatic and Extrahepatic Cholestasis

1972 • 115 citations

TREATMENT OF GILBERT'S SYNDROME WITH PHENOBARBITONE

1970 • 98 citations

Defective Bromosulfophthalein Clearance in Patients with Constitutional Hepatic Dysfunction (Gilbert's Syndrome)

1972 • 96 citations

Effect of sodium phenobarbital on bilirubin metabolism in an infant with congenital, nonhemolytic, unconjugated hyperbilirubinemia, and kernicterus

1969 • 83 citations

ORGANIC ANION-BINDING PROTEIN IN RAT LIVER: DRUG INDUCTION AND ITS PHYSIOLOGIC CONSEQUENCE

1969 • 77 citations

Bilirubin Turnover Studies in Normal and Pathologic States Using Bilirubin-^14C

1968 • 62 citations

LATENT LIVER DISEASE IN PERSONS RECOVERED FROM CATARRHAL JAUNDICE AND IN OTHERWISE NORMAL MEDICAL STUDENTS AS REVEALED BY THE BILIRUBIN EXCRETION TEST

1942 • 60 citations

Studies on the biosynthesis production of bilirubin-C14: an improved method utilizing delta-aminolevulinic acid-4-C14 in dogs.

1966 • 56 citations

BILIRUBIN GLUCURONYL TRANSFERASE ACTIVITY IN LIVER DISEASE.

1964 • 48 citations

INCREASE OF PENTOBARBITONE METABOLISM INDUCED IN RATS PRETREATED WITH SOME CENTRALLY ACTING COMPOUNDS

1962 • 48 citations

TREATMENT OF CHRONIC INTRAHEPATIC CHOLESTASIS WITH PHENOBARBITONE

1967 • 45 citations

AN ASSESSMENT OF RED CELL SURVIVAL IN IDIOPATHIC UNCONJUGATED HYPERBILIRUBINÆMIA (GILBERT'S SYNDROME) BY THE USE OF RADIOACTIVE DIISOPROPYLFLUOROPHOSPHATE AND CHROMIUM

1967 • 41 citations

Reduction in serum bilirubin by phenobarbital in adult unconjugated hyperbilirubinaemia

1968 • 39 citations

Hepatic bilirubin UDP-glucuronyl transferase activity and cytochrome P450 content in a surgical population, and the effects of preoperative drug therapy.

1973 • 36 citations

Clinical aspects of unconjugated hyperbilirubinemia.

1972 • 11 citations

The Dynamics and Control of Chemical Processes in Man

1970 • 8 citations

Augmentation of Bilirubin UDP Glucuronyltransferase Activity in Rat Liver Homogenates by Glutethimide

1972 • 6 citations

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Effect of Phenobarbitone on Plasma [14C]Bilirubin Clearance in Patients with Unconjugated… (1974) – Clinical Science | Metascience Observatory Explorer