Endomitosis of Human Megakaryocytes Are Due to Abortive Mitosis

SKP1 Connects Cell Cycle Regulators to the Ubiquitin Proteolysis Machinery through a Novel Motif, the F-Box

1996 • 1,386 citations

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

1994 • 1,328 citations

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1994 • 1,138 citations

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

1994 • 1,081 citations

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI

1994 • 987 citations

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1995 • 940 citations

Mitosis in transition

1994 • 745 citations

Thrombopoietin: the primary regulator of platelet production [see comments]

1995 • 691 citations

c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

1994 • 689 citations

Identification of a Human Mitotic Checkpoint Gene: hsMAD2

1996 • 609 citations

Ordering S phase and M phase in the cell cycle

1994 • 596 citations

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor

1993 • 569 citations

Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast

1995 • 561 citations

Driving the cell cycle: M phase kinase, its partners, and substrates

1990 • 404 citations

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

1995 • 369 citations

Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional

1995 • 369 citations

The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins

1994 • 346 citations

Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.

1995 • 344 citations

A Three-Dimensional View of Precursor Messenger RNA Metabolism Within the Mammalian Nucleus

1993 • 335 citations

Establishment and characterization of a human leukemic cell line with megakaryocytic features: dependency on granulocyte-macrophage colony-stimulating factor, interleukin 3, or erythropoietin for growth and survival.

1991 • 309 citations

Regulation of megakaryocytopoiesis

1989 • 305 citations

Cholinesterase as a Possible Marker for Early Cells of the Megakaryocytic Series

1973 • 297 citations

Budding Yeast SKP1 Encodes an Evolutionarily Conserved Kinetochore Protein Required for Cell Cycle Progression

1996 • 284 citations

The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors

1995 • 283 citations

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila

1991 • 281 citations

Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics.

1995 • 279 citations

Differential expression of a phosphoepitope at the kinetochores of moving chromosomes

1993 • 231 citations

Effects of the recombinant hematopoietic growth factors interleukin-3, interleukin-6, stem cell factor, and leukemia inhibitory factor on the megakaryocytic differentiation of CD34+ cells

1993 • 211 citations

Endoreduplication in Maize Endosperm: Involvement of M Phase—Promoting Factor Inhibition and Induction of S Phase—Related Kinases

1995 • 208 citations

Thrombopoietin-Induced Differentiation of a Human Megakaryoblastic Leukemia Cell Line, CMK, Involves Transcriptional Activation of p21^WAF1/Cip1 by STAT5

1997 • 189 citations

Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytes.

1981 • 188 citations

Regulation of megakaryocyte phenotype in human erythroleukemia cells.

1990 • 168 citations

Expression of CD34 and platelet glycoproteins during human megakaryocytic differentiation

1992 • 167 citations

CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo

1997 • 164 citations

Immunological study of in vitro maturation of human megakaryocytes

1984 • 162 citations

Ultrastructure of Human Bone Marrow Cell Maturation

1976 • 157 citations

Mitosis

1989 • 155 citations

Thrombopoietin-induced Polyploidization of Bone Marrow Megakaryocytes Is Due to a Unique Regulatory Mechanism in Late Mitosis

1997 • 143 citations

Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase.

1995 • 127 citations

Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines.

1994 • 124 citations

Cyclin D3 is essential for megakaryocytopoiesis

1995 • 120 citations

Two-color flow cytometric measurement of DNA distributions of rat megakaryocytes in unfixed, unfractionated marrow cell suspensions

1984 • 118 citations

Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand

1995 • 114 citations

The Cell Cycle in Polyploid Megakaryocytes Is Associated with Reduced Activity of Cyclin B1-dependent Cdc2 Kinase

1996 • 113 citations

Novel alterations in CDK1/cyclin B1 kinase complex formation occur during the acquisition of a polyploid DNA content.

1996 • 99 citations

The pebble gene is required for cytokinesis in Drosophila

1992 • 94 citations

The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1

1992 • 90 citations

Real time observation of anaphase in vitro.

1996 • 65 citations

Endoreplication in megakaryoblastic cell lines is accompanied by sustained expression of G1/S cyclins and downregulation of cdc25C.

1996 • 60 citations

Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements.

1993 • 60 citations

Endomitosis: A reappraisal

1983 • 59 citations

Immature megakaryocytes in the mouse: In vitro relationship to megakaryocyte progenitor cells and mature megakaryocytes

1982 • 52 citations

Generation cycle of rat megakaryocytes

1968 • 50 citations

The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors

1995 • 27 citations

EXPRESSION OF CYCLINS-B AND CYCLINS-E IN INDIVIDUAL MOLT-4 CELLS AND IN STIMULATED HUMAN-LYMPHOCYTES DURING THEIR PROGRESSION THROUGH THE CELL-CYCLE

1993 • 19 citations

Nucleotide sequence analysis of the_l and v_h domains of five human igm directed to lamin b. evidence for an antigen‐driven process in the generation of human autoantibodies to lamin b

1993 • 15 citations

CYCLES OF REDUPLICATION IN MEGAKARYOCYTE NUCLEI

1969 • 11 citations

[Expression of cyclin B in megakaryocytes and cells of other hematopoietic lines].

1993 • 11 citations