Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of <scp>d</scp> -1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Current protocols in molecular biology

1988 • 4,543 citations

The physical map of the whole E. coli chromosome: Application of a new strategy for rapid analysis and sorting of a large genomic library

1987 • 1,768 citations

Pedigrees of some mutant strains of Escherichia coli K-12

1972 • 1,742 citations

Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

1993 • 1,158 citations

Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate‐independent pathway

1997 • 700 citations

Glyceraldehyde 3-Phosphate and Pyruvate as Precursors of Isoprenic Units in an Alternative Non-mevalonate Pathway for Terpenoid Biosynthesis

1996 • 473 citations

Nucleotide and deduced polypeptide sequences of the photosynthetic reaction-center, B870 antenna, and flanking polypeptides from R. capsulata

1984 • 438 citations

Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus

1996 • 365 citations

Terpenoid biosynthesis from 1-deoxy- <scp>d</scp> -xylulose in higher plants by intramolecular skeletal rearrangement

1997 • 364 citations

Biosynthesis of isoprenoid compounds

1982 • 362 citations

Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution.

1992 • 355 citations

A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway

1998 • 351 citations

CLA1, a novel gene required for chloroplast development, is highly conserved in evolution

1996 • 292 citations

Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin.

1996 • 259 citations

Is Isoprene Emitted by Plants Synthesized via the Novel Isopentenyl Pyrophosphate Pathway?

1997 • 148 citations

Monoterpenoid essential oils are not of mevalonoid origin

1997 • 147 citations

Cloning and Nucleotide Sequence of the ispA Gene Responsible for Farnesyl Diphosphate Synthase Activity in Escherichia coli11

1990 • 129 citations

Biosynthesis of the thiazole moiety of thiamin (vitamin B1) in higher plant chloroplasts.

1991 • 127 citations

The Biogenetic Anatomy of Vitamin B6

1996 • 119 citations

Transcription of ftsZ oscillates during the cell cycle of Escherichia coli.

1993 • 111 citations

Practice of thin layer chromatography

1978 • 100 citations

Isoprenoid biosynthesis in bacteria: Two different pathways?

1993 • 97 citations

The Identification of Escherichia Coli ispB (CEL) Gene Encoding the Octaprenyl Diphosphate Synthase

1994 • 87 citations

Biosynthesis of vitamin B6: incorporation of D-1-deoxyxylulose

1989 • 84 citations

1-Deoxy-D-threo-2-pentulose: the precursor of the five-carbon chain of the thiazole of thiamine

1981 • 66 citations

Biochemical Genetics of the -Keto Acid Dehydrogenase Complexes of Escherichia coli K12: Isolation and Biochemical Properties of Deletion Mutants

1977 • 62 citations

Temperature-sensitive production of rabbit muscle glycogen phosphorylase in Escherichia coli

1991 • 50 citations

1-Deoxy-<scp>D</scp>-xylulose

1995 • 47 citations

Incorporation of [2,3-13C2]- and [2,4-13C2]-d-1-Deoxyxylulose into Ubiquinone of Escherichia coli via the Mevalonate-Independent Pathway for Isoprenoid Biosynthesis

1998 • 47 citations

Biosynthesis of Isoprenoid Compounds

1961 • 47 citations

Biosynthesis of Vitamin B6: Origin of Pyridoxine by the Union of Two Acyclic Precursors, 1-Deoxy-D-xylulose and 4-Hydroxy-L-threonine

1995 • 42 citations

Formation of 1-deoxy-ketoses by pyruvate dehydrogenase and acetoin dehydrogenase.

1986 • 38 citations

PCR2: A practical approach

1996 • 35 citations

Membrane-bound phosphatases in Escherichia coli: sequence of the pgpA gene

1988 • 27 citations

Formation of 1-deoxy-D-threo-pentulose and 1-deoxy-L-threo-pentulose by cell-free extracts of microorganisms.

1984 • 26 citations

The origin of the carbon chain in the thiazole moiety of thiamine in Escherichia coli: Incorporation of deuterated 1-deoxy-D-threo-2-pentulose

1981 • 25 citations

A diverse transketolase family that includes the RecP protein of Streptococcus pneumoniae, a protein implicated in genetic recombination

1993 • 24 citations

5-Hydroxypentane-2,3-dione (laurencione), a bacterial metabolite of 1-deoxy-D- threo -pentulose

1998 • 10 citations