Regulation of the Human C-reactive Protein Gene in Transgenic Mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Acute Phase Proteins with Special Reference to C-Reactive Protein and Related Proteins (Pentaxins) and Serum Amyloid A Protein

1983 • 1,283 citations

Human CD2 3′-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

1989 • 385 citations

Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice.

1992 • 288 citations

Dual control of C-reactive protein gene expression by interleukin-1 and interleukin-6.

1989 • 270 citations

Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene.

1987 • 178 citations

Constitutive and IL-6-induced nuclear factors that interact with the human C-reactive protein promoter.

1990 • 176 citations

Structure and expression of the human haptoglobin locus.

1985 • 147 citations

Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites.

1990 • 146 citations

Hepatic acute phase reaction in vivo and in vitro

1989 • 132 citations

Inducible and tissue-specific expression of human C-reactive protein in transgenic mice.

1987 • 127 citations

Identification of sequences responsible for acute-phase induction of human C-reactive protein

1988 • 87 citations

Mouse C-reactive protein. Generation of cDNA clones, structural analysis, and induction of mRNA during inflammation

1990 • 82 citations

Negative regulation of transcription in eukaryotes

1993 • 80 citations

cis-acting elements responsible for interleukin-6 inducible C-reactive protein gene expression.

1990 • 70 citations

Transcriptional Insulation of the Human Keratin 18 Gene in Transgenic Mice

1993 • 52 citations

Inducible formation of liver tumors in transgenic mice.

1993 • 20 citations

Sequence of the region 5′ to the negative regulatory genePH080ofSaccharomyces cerevisiae

1987 • 4 citations