Preferential induction of apoptosis in mouse CD4⁺CD8⁺αβTCR^IoCD3ε^Io thymocytes by zinc

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Apoptosis and Programmed Cell Death in Immunity

1992 • 1,105 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor

1986 • 878 citations

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77

1994 • 551 citations

Calcium‐activated DNA fragmentation kills immature thymocytes

1989 • 533 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Cascade Induction of c-fos, c-myc, and Heat Shock 70K Transcripts during Regression of the Rat Ventral Prostate Gland

1988 • 355 citations

Structural and functional analysis of the human metallothionein-IA gene: Differential induction by metal ions and glucocorticoids

1984 • 331 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Evaluation of glucocorticoid‐induced DNA fragmentation in mouse thymocytes by flow cytometry

1991 • 241 citations

Programmed death of autoreactive thymocytes

1990 • 224 citations

Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes.

1988 • 189 citations

Physiology of Zinc: General Aspects

1989 • 186 citations

In vivo and in vitro clonal deletion of double-positive thymocytes.

1992 • 172 citations

Evidence for early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid-mediated apoptosis.

1991 • 157 citations

Cadmium induces transcription of proto-oncogenes c-jun and c-myc in rat L6 myoblasts.

1990 • 147 citations

The Heat Shock Response in HeLa Cells is Accompanied by Elevated Expression of the c-fos Proto-Oncogene

1987 • 147 citations

The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene.

1987 • 106 citations

Inhibition of apoptosis by zinc: A reappraisal

1992 • 103 citations

Regulation of protein kinase C activity by cooperative interaction of Zn2+ and Ca2+.

1987 • 103 citations

Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry

1992 • 99 citations

Protein kinase-C involvement in thymocyte apoptosis induced by hydrocortisone

1990 • 98 citations

Physiological role for zinc in prevention of apoptosis (gene-directed death).

1991 • 96 citations

Synergy between zinc and phorbol ester in translocation of protein kinase C to cytoskeleton

1990 • 92 citations

Programmed cell death : the cellular and molecular biology of apoptosis

1993 • 90 citations

Stimulation of human peripheral lymphocytes by Zn2+ in vitro

1970 • 89 citations

Metal-dependent binding of a factor in vivo to the metal-responsive elements of the metallothionein 1 gene promoter.

1987 • 87 citations

Glucocorticoids and irradiation-induced apoptosis in normal murine bone marrow B-lineage lymphocytes as determined by flow cytometry.

1993 • 86 citations

Inhibition of both etoposide-induced DNA fragmentation and activation of poly(ADP-ribose) synthesis by zinc ion

1990 • 78 citations

Activation of the c-jun protooncogene in human myeloid leukemia cells treated with etoposide.

1991 • 74 citations

Trace Element-Gene Interactions

2009 • 63 citations

Interaction between protein kinase C and regulatory ligand is enhanced by a chelatable pool of cellular zinc

1990 • 62 citations

Coordinate regulation of zinc metabolism and metallothionein gene expression in rats

1986 • 61 citations

Heavy metals induce expression of the TPA‐inducible sequence (TIS) genes

1991 • 57 citations

Calmodulin, zinc, and calcium in cellular and membrane regulation: An interpretive review

1980 • 55 citations

Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells

1990 • 46 citations

Systemic Transport of Zinc

1989 • 45 citations

Zinc as a possible mediator of signal transduction in T lymphocytes.

1989 • 42 citations

Zinc increases the affinity of phorbol ester receptor in T lymphocytes

1988 • 41 citations

Cell surface and cell cycle analysis of metal‐induced murine T cell proliferation

1986 • 36 citations

The tumor promoter tetradecanoyl-phorbol-acetate (TPA) elicits the redistribution of zinc in subcellular fractions of rabbit thymocytes measured by X-ray fluorescence

1987 • 19 citations

Intracellular calcium binding proteins as targets for heavy metal ions

1986 • 16 citations

Glucocorticoid Regulation of Protooncogene Expression and Cellular Proliferation

1987 • 5 citations

Mitogenic Effect of Zinc on Lymphocytes from Strains of Mice That are Either High or Low-Responder to T-Cell Mitogens

1992 • 1 citations