Genetic alterations in localized prostate cancer: Identification of a common region of deletion on chromosome arm 18q

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

1989 • 3,458 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

A second-generation linkage map of the human genome

1992 • 1,721 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.

1992 • 1,063 citations

Allelic loss of chromosomes 16q and 10q in human prostate cancer.

1990 • 456 citations

p53 is mutated in a subset of advanced-stage prostate cancers.

1993 • 377 citations

Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer.

1993 • 364 citations

Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma

1991 • 286 citations

A variation in the structure of the protein-coding region of the human p53 gene

1988 • 286 citations

Important advances in oncology 1994

1994 • 282 citations

Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers.

1992 • 215 citations

Frequency and pattern of karyotypic abnormalities in human prostate cancer.

1990 • 172 citations

Cytogenetic analysis of 57 primary prostatic adenocarcinomas

1992 • 169 citations

Report of the committee on chromosome and gene loss in human neoplasia

1991 • 158 citations

Allelotyping of human prostatic adenocarcinoma

1991 • 153 citations

Chromosome study of five cancers of the prostate

1985 • 152 citations

Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas.

1993 • 139 citations

Somatic mutations and human breast cancer. A Status Report

1992 • 90 citations

Human chromosome 8 linkage map based on short tandem repeat polymorphisms: Effect of genotyping errors

1992 • 66 citations

Analysis of prostatic tumor cultures using fluorescence in-situ hybridization (FISH)

1992 • 55 citations

Numerical chromosomal aberrations in prostate cancer: correlation with morphology and cell kinetics

1993 • 36 citations

Absence of p53 germ-line mutations in bilateral breast cancer patients

1992 • 32 citations

Molecular Genetics and Human Prostatic Carcinoma

1991 • 24 citations

Programmed cell death: Bcl-2.

1993 • 24 citations