Preclinical profile of the mixed 5-HT1A/5-HT2A receptor antagonist S 21357

Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices

1983 • 497 citations

Defense system psychopharmacology: An ethological approach to the pharmacology of fear and anxiety

1993 • 359 citations

Buspirone and diazepam in anxiety: a controlled study.

1982 • 305 citations

The Influence of Ritanserin, a Serotonin Antagonist, in Anxiety Disorders: A Double-blind Placebo-controlled Study versus Lorazepam

1985 • 223 citations

Alterations of central serotonin and dopamine turnover in rats treated with ipsapirone and other 5-hydroxytryptamine1A agonists with potential anxiolytic properties.

1988 • 205 citations

Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic agents

1993 • 194 citations

Involvement of 5-HT2 receptors in the wet-dog shake behaviour induced by 5-hydroxytryptophan in the rat

1983 • 189 citations

5-HT receptors as targets for the development of novel anxiolytic drugs: models, mechanisms and future directions

1993 • 168 citations

New concepts in anxiety

1990 • 157 citations

Is Buspirone Effective for Panic Disorder?

1990 • 153 citations

Serotonin; From cell biology to pharmacology and therapeutics

1991 • 153 citations

Piperazine derivatives including the putative anxiolytic drugs, buspirone and ipsapirone, are agonists at 5-HT1A receptors negatively coupled with adenylate cyclase in hippocampal neurons

1987 • 136 citations

Serotonin; From cell biology to pharmacology and therapeutics

1991 • 126 citations

Rigidity, sensitivity and quality of attachment: the role of maternal rigidity in the early socio-emotional development of premature infants.

1993 • 120 citations

Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine

1995 • 115 citations

Comparison of buspirone in two separate studies.

1982 • 106 citations

Further evidence that the mouse defense test battery is useful for screening anxiolytic and panicolytic drugs: Effects of acute and chronic treatment with alprazolam

1995 • 101 citations

K+ channel and 5-hydroxytryptamine1A autoreceptor interactions in the rat dorsal raphe nucleus: Anin vitro electrophysiological study

1991 • 95 citations

The relative efficacy of high‐dose buspirone and alprazolam in the treatment of panic disorder: a double‐blind placebo‐controlled study

1993 • 79 citations

A model of ???antipredator??? defense in Swiss-Webster mice

1995 • 78 citations

A Double-Blind, Placebo-Controlled Study Comparing the Efficacy and Safety of Ipsapirone Versus Lorazepam in Patients With Generalized Anxiety Disorder

1993 • 76 citations

Effects of serotonin receptor antagonists on PAG stimulation induced aversion: different contributions of 5HT1, 5HT2 and 5HT3 receptors

1989 • 74 citations

Neurotransmitters in the Dorsal Periaqueductal Grey and Animal Models of Panic Anxiety

1991 • 73 citations

(?)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain

1993 • 73 citations

Further assessment of the antagonist properties of the novel and selective 5-HT1A receptor ligands (+)-WAY 100 135 and SDZ 216–525

1993 • 70 citations

Predator-elicited plight responses in Swiss-Webster Mice: An experimental model of panic attacks

1996 • 66 citations

Interaction of ?-adrenoceptor agonists with the serotonergic system in rat brain

1981 • 65 citations

Buspirone in Social Phobia

1993 • 63 citations

Serotonergic Anxiolytics in the Treatment of Panic Disorder: A Controlled Study With Buspirone

1989 • 62 citations

A pilot study of buspirone in the treatment of social phobia

1991 • 58 citations

Opposite control mediated by central 5-HT1A and non-5-HT1A (5-HT1B or 5-HT1C) receptors on periaqueductal gray aversion

1989 • 54 citations

S 14506: A novel, potent, high‐efficacy 5‐HT_1A agonist and potential anxiolytic agent

1992 • 51 citations

5-HT1A agonists modulate mouse antipredator defensive behavior differently from the 5-HT2A antagonist pirenperone

1995 • 49 citations

New methoxy-chroman derivatives, 4[N-(5-methoxy-chroman-3-yl)N- propylamino]butyl-8-azaspiro-(4,5)-decane-7,9-dione [(+/-)-S 20244] and its enantiomers, (+)-S 20499 and (-)-S 20500, with potent agonist properties at central 5-hydroxytryptamine1A receptors.

1993 • 40 citations

Preclinical pharmacology of FG5893: a potential anxiolytic drug with high affinity for both 5-HT1A and 5-HT2A receptors

1994 • 39 citations

A placebo-controlled double-blind multicenter trial of two doses of ipsapirone versus diazepam in generalized anxiety disorder

1993 • 33 citations

Slow wave sleep and 5-HT2 receptor sensitivity in generalised anxiety disorder: a pilot study with ritanserin

1992 • 27 citations

Anticonflict and discriminative stimulus effects of the 5‐HT_1A compounds WY‐47,846 and WY‐48,723 and the mixed 5‐HT_1A agonist/5‐HT₂ antagonist WY‐50,324 in pigeons

1991 • 26 citations

Interactions of lesopitron (E-4424) with central 5-HT1A receptors: in vitro and in vivo studies in the rat

1994 • 21 citations

The effect of buspirone on panic disorder: a case report.

1987 • 15 citations

S 14671: A novel naphthylpiperazane 5-HT1A agonist of high efficacy and exceptional in vivo potency

1991 • 10 citations

An animal model of panic disorder?

1991 • 7 citations

ON FOOT LAMENESS IN HORSES.

1828 • 4 citations

An Animal Model of Panic Disorder

1992 • 2 citations

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