Effects of d- and l-amphetamine on habituation and sensitization of the acoustic startle response in rats

Habituation: A dual-process theory.

1970 • 2,096 citations

The Pharmacological Basis of Therapeutics

1971 • 1,765 citations

Evidence for dopamine receptor stimulation by apomorphine

1967 • 910 citations

BLOCKADE OF ENDOGENOUS NOREPINEPHRINE SYNTHESIS BY ALPHA-METHYL-TYROSINE, AN INHIBITOR OF TYROSINE HYDROXYLASE.

1965 • 813 citations

Conditioned fear as revealed by magnitude of startle response to an auditory stimulus.

1951 • 649 citations

Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas.

1969 • 445 citations

Antiamphetamine effects following inhibition of tyrosine hydroxylase.

1966 • 445 citations

Biochemical and Histochemical Studies on the Effects of Imipramine‐like Drugs and (+)‐Amphetamine on Central and Peripheral Catecholamine Neurons

1966 • 414 citations

Regional studies of catecholamines in the rat brain. IV. Effects of drugs on the disposition and metabolism of H3-norepinephrine and H3-dopamine.

1966 • 307 citations

A comparison of the capacities of isomers of amphetamine, deoxypipradrol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptosomal preparations of rat cerebral cortex, hypothalamus and striatum and into adrenergic nerves of rabbit aorta.

1972 • 296 citations

Modification of the startle reflex in the rat by changes in the auditory and visual environments.

1971 • 261 citations

Acoustic variables in the modification of startle reaction in the rat.

1965 • 254 citations

Amphetamine: Differentiation by d and l Isomers of Behavior Involving Brain Norepinephrine or Dopamine

1970 • 252 citations

Differential effects of D- and L-amphetamine on behavior and on catecholamine disposition in dopamine and norepinephrine containing neurons of rat brain

1971 • 235 citations

Involvement of nigro-striatal neurons in the in vivo release of dopamine by amphetamine, amantadine and tyramine.

1973 • 229 citations

Release of norepinephrine from hypothalamus and amygdala by rewarding medial forebrain bundle stimulation and amphetamine.

1969 • 227 citations

Uptake of [3H]-catecholamines by homogenates of rat corpus striatum and cerebral cortex: Effects of amphetamine analogues

1973 • 215 citations

Evidence that the central action of amphetamine is mediated via catecholamines

1966 • 189 citations

The relative importance of dopaminergic and noradrenergic neuronal systems for the stimulation of locomotor activity induced by amphetamine and other drugs

1973 • 184 citations

Behavioural and biochemical comparison of amphetamine derivatives, cocaine, benztropine and tricyclic anti-depressant drugs

1972 • 165 citations

Selectivity of release of norepinephrine, dopamine and 5-hydroxytryptamine by amphetamine in various regions of rat brain

1973 • 161 citations

Conditioned frustration as a learned drive.

1963 • 151 citations

Diethyldithiocarbamate and amphetamine stereotype behaviour

1966 • 133 citations

A Replication and Extension

1968 • 129 citations

Habituation of startle response under incremental sequence of stimulus intensities.

1969 • 125 citations

Aminergic mechanisms in corpus striatum and amphetamine-induced stereotyped behaviour

1967 • 119 citations

Sensitization of the rat startle response by noise.

1974 • 118 citations

Lesions in corpus striatum and cortex of rat brains and the effect on pharmacologically induced stereotyped, aggressive and cataleptic behaviour

1970 • 116 citations

Amphetamine Response in Rat after Dopamine Neurone Destruction

1972 • 116 citations

6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: Effect on amphetamine-induced stereotyped behavior in rats

1974 • 116 citations

Formation of Phenolic Acids in Brain after Administration of 3,4‐Dihydroxyphenylalanine

1962 • 103 citations

Dopamine and norepinephrine uptake by rat brain synaptosomes: relative inhibitory potencies of 1- and d-amphetamine and amantadine.

1973 • 83 citations

Effects of d-amphetamine and restraint on the content of norepinephrine and dopamine in rat brain

1963 • 79 citations

Characteristics of amphetamine-induced release of norepinephrine from rat cerebral cortex in vitro.

1972 • 75 citations

The fate of C14-dihydroxyphenylalanine (C14-dopa) in the whole mouse.

1970 • 73 citations

D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.

1975 • 71 citations

Effect of D-Amphetamine on Rat Brain Noradrenaline and Serotonin

1961 • 70 citations

On the role of norepinephrine biosynthesis in the central action of amphetamine

1967 • 70 citations

Functional and biochemical effects of d- and l-amphetamine on central catecholamine neurons

1971 • 67 citations

Signal-to-noise ratio as a predictor of startle amplitude and habituation in the rat.

1974 • 66 citations

Effects of amphetamine on the contents of norepinephrine and its metabolites in the effluent of perfused cerebral ventricles of the cat

1970 • 64 citations

Studies on the concurrent behavioral and neurochemical effects of psychoactive drugs using the push-pull cannula.

1972 • 64 citations

Hyperlipoproteinemia in alcoholic subjects

1973 • 62 citations

Role of catecholamines in the anorectic effects of amphetamine in rats

1974 • 61 citations

Electrophysiological effects of amphetamine on dopaminergic neurons

1973 • 60 citations

Differential retention of sensitization and habituation of the startle response in the rat.

1972 • 58 citations

Acute effects of alpha-methyltyrosine on brain catecholamine levels and on spontaneous and amphetamine-stimulated motor activity in mice.

1969 • 58 citations

The role of brain norepinephrine in the anorexic effects of dextroamphetamine and monoamine oxidase inhibitors in the rat

1971 • 53 citations

Behavioral effects of amphetamine in rats with lesions in the corpus striatum.

1974 • 52 citations

The induction and antagonism of central nervous system stimulant-induced stereotyped behavior in the cat

1972 • 47 citations

Conditioned fear and magnitude of startle response: A replication and extension.

1966 • 44 citations

Effects of lysergic acid diethylamide (LSD) on habituation and sensitization of the startle response in the rat

1974 • 43 citations

A comparison of the locomotor stimulant properties of amantadine and l- and d-amphetamine in mice

1972 • 41 citations

Startle response circadian rhythm in rats: Lack of correlation with motor activity

1970 • 39 citations

The effects of methylamphetamine on stereotyped behaviour, activity, startle, and orienting responses

1972 • 36 citations

The effects of l-Dopa, clonidine, and apomorphine on the acoustic startle reaction in rats

1974 • 33 citations

The effects of prior aversive stimulation on the behavioral and physiological responses to intense acoustic stimuli in the rat

1974 • 31 citations

ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS

1973 • 30 citations

The effects of dimethoxyphenylethylamine and mescaline on classical conditioning in rats as measured by the potentiated startle response

1967 • 28 citations

Effect of Amphetamine and Catecholamines on Startle Response and General Motor Activity of Albino Rats

1966 • 26 citations

The inhibition of the acoustic startle reaction in rats by food and water deprivation

1972 • 26 citations

Amphetamine isomers: Influences on locomotor and stereotyped behavior of cats

1974 • 22 citations

Estimation of chronic dopamine release from the caudate nucleus of theMacaca mulatta

1974 • 14 citations

Effects of 6-hydroxydopamine and alpha-methyl-para-tyrosine on the acoustic startle response in rats

1975 • 14 citations

Magnitude of sound-induced startle response as a function of primary hunger drive.

1967 • 6 citations