Binding of the Drosophila transformer and transformer-2 proteins to the regulatory elements of doublesex primary transcript for sex-specific RNA processing.

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides

1989 • 685 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

Sex in flies: the splice of life

1989 • 468 citations

Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene

1987 • 406 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

SEX AND THE SINGLE CELL. I. ON THE ACTION OF MAJOR LOCI AFFECTING SEX DETERMINATION IN DROSOPHILA MELANOGASTER

1980 • 355 citations

Binding of the Drosophila Sex-lethal gene product to the alternative splice site of transformer primary transcript

1990 • 333 citations

Control of doublesex Alternative Splicing by transformer and transformer-2 in Drosophila

1991 • 333 citations

The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster

1988 • 284 citations

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

1988 • 266 citations

Mechanisms of Alternative Pre-mRNA Splicing

1991 • 257 citations

Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro

1991 • 244 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1991 • 224 citations

Positive Control of Pre-mRNA Splicing in Vitro

1992 • 199 citations

Regulation of doublesex pre-mRNA processing occurs by 3'-splice site activation.

1991 • 184 citations

A molecular analysis of doublesex, a bifunctional gene that controls both male and female sexual differentiation in Drosophila melanogaster.

1988 • 169 citations

Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns.

1990 • 169 citations

The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins

1989 • 156 citations

The human U1-70K snRNP protein: cDNA cloning, chromosomal localization, expression, alternative splicing and RNA-binding

1987 • 148 citations

Developmental expression of a regulatory gene is programmed at the level of splicing.

1987 • 143 citations

A nuclear cap binding protein from HeLa cells

1990 • 78 citations

Sex-specific gene expression in somatic tissues of Drosophila melanogaster

1988 • 41 citations

The control of sexual development in Drosophila melanogaster: genetic and molecular analysis of a genetic regulatory hierarchy — a minireview

1989 • 13 citations