Hyperlipidemia and Coronary Disease

Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)

1993 • 28,274 citations

Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia

1987 • 3,889 citations

The Lipid Research Clinics Coronary Primary Prevention Trial Results

1984 • 2,673 citations

The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

1992 • 2,655 citations

Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study.

1986 • 2,283 citations

Regression of Coronary Artery Disease as a Result of Intensive Lipid-Lowering Therapy in Men with High Levels of Apolipoprotein B

1990 • 2,192 citations

Can lifestyle changes reverse coronary heart disease?

1990 • 2,122 citations

The pathogenesis of coronary artery disease and the acute coronary syndromes (First of two parts)

1992 • 1,958 citations

Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin

1986 • 1,857 citations

Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT)

1986 • 1,758 citations

Beneficial Effects of Combined Colestipol-Niacin Therapy on Coronary Atherosclerosis and Coronary Venous Bypass Grafts

1987 • 1,651 citations

Incidence of Coronary Heart Disease and Lipoprotein Cholesterol Levels

1986 • 1,464 citations

Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease.

1980 • 1,450 citations

Regular physical exercise and low-fat diet. Effects on progression of coronary artery disease.

1992 • 1,349 citations

Is Relationship Between Serum Cholesterol and Risk of Premature Death From Coronary Heart Disease Continuous and Graded?

1986 • 1,248 citations

By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease?

1994 • 1,235 citations

Effect of Partial Ileal Bypass Surgery on Mortality and Morbidity from Coronary Heart Disease in Patients with Hypercholesterolemia

1990 • 999 citations

Secondary prevention of vascular disease by prolonged antiplatelet treatment

1988 • 962 citations

Effects of intensive multiple risk factor reduction on coronary atherosclerosis and clinical cardiac events in men and women with coronary artery disease. The Stanford Coronary Risk Intervention Project (SCRIP).

1994 • 896 citations

Seven Countries

1980 • 856 citations

Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study (STARS)

1992 • 847 citations

Lipid Research Clinics Program

1984 • 837 citations

Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease.

1993 • 833 citations

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1991 • 813 citations

Regression of Coronary Atherosclerosis During Treatment of Familial Hypercholesterolemia With Combined Drug Regimens

1990 • 793 citations

Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI Type II Coronary Intervention Study.

1984 • 685 citations

Platelet Function in Hyperlipoproteinemia

1974 • 682 citations

The Effect of Warfarin on Mortality and Reinfarction after Myocardial Infarction

1990 • 651 citations

Coronary Angiographic Changes with Lovastatin Therapy: The Monitored Atherosclerosis Regression Study (MARS)

1993 • 637 citations

Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia.

1994 • 602 citations

Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.

1994 • 504 citations

National cholesterol education program: Second report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel II)

1994 • 469 citations

Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolaemic patients

1993 • 462 citations

Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications.

1989 • 461 citations

The Value of Lowering Cholesterol after Myocardial Infarction

1990 • 427 citations

Dipyridamole

1987 • 397 citations

Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischaemic death

1989 • 396 citations

Effect of Cholesterol on Production of Thromboxane B₂by Platelets in Vitro

1980 • 322 citations

Influence of arterial damage and wall shear rate on platelet deposition. Ex vivo study in a swine model.

1986 • 293 citations

Effects of pravastatin in patients with serum total cholesterol levels from 5.2 to 7.8 mmol/liter (200 to 300 mg/dl) plus two additional atherosclerotic risk factors

1993 • 176 citations

Increased thromboxane biosynthesis in type IIa hypercholesterolemia.

1992 • 168 citations

Abnormalities of cholesterol-phospholipid composition in platelets and low-density lipoproteins of human hyperbetalipoproteinemia.

1977 • 138 citations

Intracellular mechanisms in the activation of human platelets by low-density lipoproteins

1987 • 101 citations

Increased fibrinogen binding to platelets from patients with familial hypercholesterolemia.

1986 • 69 citations

Simvastatin reduces platelet thromboxane formation and restores normal platelet sensitivity against prostacyclin in type IIa hypercholesterolemia.

1989 • 61 citations

Oral verapamil inhibits platelet thrombus formation in humans.

1994 • 45 citations

Sick vessel syndrome. Can atherosclerotic arteries recover?

1994 • 34 citations

Antithrombotic properties of transdermal nitroglycerin in stable angina pectoris

1994 • 33 citations

Cod liver oil alters platelet-arterial wall response to injury in pigs.

1992 • 27 citations

Reduction of LDL cholesterol by pravastatin does not influence platelet activation in patients with mild hypercholesterolaemia at risk of coronary heart disease.

1991 • 16 citations

Deleted Work

1955 • 0 citations