Suppression of NFκB activation and NFκB‐dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5‐lipoxygenase

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 • 1,421 citations

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

1990 • 1,377 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 • 1,129 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors.

1993 • 819 citations

Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.

1991 • 649 citations

The inducible transcription factor NF-κB: structure-function relationship of its protein subunits

1993 • 429 citations

The precursor of NF-κB p50 has IκB-like functions

1992 • 409 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

In vivo control of NF-kappa B activation by I kappa B alpha.

1993 • 326 citations

Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes.

1993 • 304 citations

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter.

1990 • 263 citations

Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase- dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes

1993 • 260 citations

Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines.

1992 • 242 citations

Reporter constructs with low background activity utilizing the cat gene

1992 • 240 citations

A Dominant Negative Protein Kinase C ζ Subspecies Blocks NF-κ B Activation

1993 • 223 citations

In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.

1989 • 220 citations

Kappa B site-dependent induction of gene expression by diverse inducers of nuclear factor kappa B requires Raf-1.

1993 • 189 citations

Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells.

1993 • 179 citations

A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation.

1993 • 128 citations

Tissue-specific regulation of IL-6 production by IL-4. Differential effects of IL-4 on nuclear factor-kappa B activity in monocytes and fibroblasts.

1993 • 93 citations

Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes

1993 • 81 citations

Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: Anti-inflammatory without gastropathy?

1993 • 74 citations

Inhibition of Phorbol Ester-Induced Cellular Adhesion by Competitive Binding of NF-κB In Vivo

1993 • 61 citations

Tumor necrosis factor-α, interleukin 1, and phorbol myristate acetate are independent activators of NF-κB which differentially activate T cells

1991 • 53 citations

Differential regulation of human progesterone receptor A and B form-mediated trans-activation by phosphorylation.

1993 • 34 citations

Characterization of the gene for the human high affinity IgE receptor (Fc epsilon RI) alpha-chain.

1993 • 34 citations

Inhibition of phorbol ester-induced cellular adhesion by competitive binding of NF-kappa B in vivo.

1993 • 32 citations

Tepoxalin, a novel immunosuppressive agent with a different mechanism of action from cyclosporin A.

1994 • 26 citations

Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs)

1991 • 20 citations

Reaction of methylated urates with 1,1diphenyl-2-picrylhydrazyl

1987 • 19 citations

Quantitation of human cellular retinoic acid-binding protein II (CRABP-II) RNA from cultured human skin fibroblast cells and human skin biopsies treated with retinoic acid

1992 • 15 citations

Differential regulation of human progesterone receptor A and B form- mediated trans-activation by phosphorylation

1993 • 14 citations