Identification of a potent adipocyte-specific enhancer: involvement of an NF-1-like factor.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Sublines of mouse 3T3 cells that accumulate lipid

1974 • 918 citations

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

1985 • 849 citations

Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells

1976 • 826 citations

A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs

1988 • 747 citations

Common DNA binding site for Fos protein complexesand transcription factor AP-1

1988 • 613 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.

1989 • 587 citations

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene

1987 • 532 citations

Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

1980 • 524 citations

Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos

1987 • 523 citations

Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development.

1983 • 476 citations

Factors involved in control of tissue-specific expression of albumin gene

1987 • 367 citations

Modularity in promoters and enhancers

1989 • 366 citations

Adipocyte P2 gene: developmental expression and homology of 5'-flanking sequences among fat cell-specific genes.

1986 • 334 citations

Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein.

1984 • 329 citations

Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA.

1983 • 318 citations

Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes.

1985 • 292 citations

Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein.

1990 • 287 citations

The SV40 enhancer contains two distinct levels of organization

1988 • 286 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?

1989 • 266 citations

Heterogeneous distribution of beta and alpha‐2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences

1987 • 241 citations

Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA.

1988 • 241 citations

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

1988 • 238 citations

Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones

1978 • 237 citations

Control of specific protein biosynthesis during the adipose conversion of 3T3 cells.

1980 • 217 citations

A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.

1990 • 217 citations

Analysis of gene expression during differentiation of adipogenic cells in culture and hormonal control of the developmental program.

1984 • 203 citations

The TGGCA protein binds to the MMTV-LTR, the adenovirus origin of replication, and the BK virus enhancer

1985 • 203 citations

Tissue-specific transcription preference as a determinant of cell tropism and leukaemogenic potential of murine retroviruses

1984 • 202 citations

A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.

1985 • 197 citations

The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded linear DNA

1984 • 191 citations

Chicken NFI/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes

1990 • 177 citations

Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

1988 • 171 citations

A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.

1989 • 170 citations

Developmentally regulated mRNAs in 3T3-adipocytes: analysis of transcriptional control.

1985 • 170 citations

Interaction of the TGGCA-binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus.

1987 • 168 citations

Structure and function of the adenovirus origin of replication

1984 • 163 citations

Purification of murine adipocyte lipid-binding protein. Characterization as a fatty acid- and retinoic acid-binding protein.

1988 • 161 citations

Recognition site of nuclear factor I, a sequence-specific DNA-binding protein from HeLa cells that stimulates adenovirus DNA replication.

1985 • 148 citations

Growth hormone regulation of the expression of differentiation-dependent genes in preadipocyte Ob1771 cells

1986 • 131 citations

The lysozyme enhancer: cell-specific activation of the chicken lysozyme gene by a far-upstream DNA element.

1986 • 118 citations

Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP.

1988 • 105 citations

The mouse mammary tumor virus long terminal repeat directs expression in epithelial and lymphoid cells of different tissues in transgenic mice

1987 • 100 citations

DEAE-dextran: Enhancement of cellular transformation induced by avian sarcoma viruses

1967 • 94 citations

The nucleotide sequence of three genes participating in the adipose differentiation of 3T3 cells.

1986 • 89 citations

Control of the adipsin gene in adipocyte differentiation. Identification of distinct nuclear factors binding to single- and double-stranded DNA.

1990 • 88 citations

Clusters of nuclear factor I binding sites identify enhancers of several papillomaviruses but alone are not sufficient for enhancer function

1989 • 87 citations

Mechanism of regulation of the 422(aP2) gene by cAMP during preadipocyte differentiation.

1989 • 82 citations

The activation of specific gene transcription in the adipose conversion of 3T3 cells

1985 • 80 citations

Developmental modulation of protein binding to beta-globin gene regulatory sites within chicken erythrocyte nuclei.

1989 • 79 citations

Biotechnology for Control of Growth and Product Quality in Swine: Implications and Acceptability

1989 • 34 citations