Interleukin-13 gene polymorphism G4257A is associated with atopic dermatitis in Japanese patients

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1980 • 4,910 citations

Interleukin-13: Central Mediator of Allergic Asthma

1998 • 2,642 citations

Severity Scoring of Atopic Dermatitis: The SCORAD Index

1993 • 2,121 citations

Requirement for IL-13 Independently of IL-4 in Experimental Asthma

1998 • 1,869 citations

THE INTERACTION OF SELECTION AND LINKAGE. I. GENERAL CONSIDERATIONS; HETEROTIC MODELS

1964 • 1,829 citations

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1999 • 1,715 citations

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

1993 • 1,084 citations

Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma

1997 • 1,069 citations

Linkage Analysis of IL4 and Other Chromosome 5q31.1 Markers and Total Serum Immunoglobulin E Concentrations

1994 • 1,025 citations

Clinical Validation and Guidelines for the SCORAD Index: Consensus Report of the European Task Force on Atopic Dermatitis

1997 • 1,005 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy

1995 • 774 citations

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

1997 • 712 citations

Genetic variants of IL-13 signalling and human asthma and atopy

2000 • 427 citations

IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells.

1995 • 424 citations

A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children

2000 • 415 citations

Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma

1998 • 396 citations

Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci

2001 • 386 citations

In vivo expression of IL-12 and IL-13 in atopic dermatitis

1996 • 380 citations

An IL-13 promoter polymorphism associated with increased risk of allergic asthma

1999 • 292 citations

An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German Multicenter Atopy Study (MAS-90)

2000 • 196 citations

Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA- memory T cells.

1997 • 196 citations

Evidence for Linkage Between Asthma/Atopy in Childhood and Chromosome 5q31-q33 in a Japanese Population

1997 • 187 citations

T CELL SUBSETS AND CYTOKINES IN ALLERGIC AND NON-ALLERGIC CHILDREN. I. ANALYSIS OF IL-4, IFN-γ AND IL-13 mRNA EXPRESSION AND PROTEIN PRODUCTION

1997 • 152 citations

Associations between IL-13 and IL-4 (mRNA and protein), vascular cell adhesion molecule-1 expression, and the infiltration of eosinophils, macrophages, and T cells in allergen-induced late-phase cutaneous reactions in atopic subjects.

1997 • 124 citations

Identifying genes predisposing to atopic eczema☆☆☆★★★

1999 • 105 citations

Antigen-Induced Airway Hyperresponsiveness, Pulmonary Eosinophilia, and Chemokine Expression in B Cell–Deficient Mice

1999 • 99 citations

Linkage of Chromosome 5q and 11q Gene Markers to Asthma-associated Quantitative Traits in Australian Children

1998 • 98 citations

A murine model of allergic rhinitis: Studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin

1998 • 85 citations

Association and Linkage of Atopic Dermatitis with Chromosome 13q12–14 and 5q31–33 Markers

2000 • 83 citations

Increased levels of IL-13 mRNA, but not IL-4 mRNA, are found in vivo in peripheral blood mononuclear cells (PBMC) of patients with atopic dermatitis (AD)

1997 • 79 citations

Linkage and association to candidate regions in Swedish atopic dermatitis families

2001 • 39 citations

IL-13 Production by Peripheral Blood Mononuclear Cells from Patients with Atopic Dermatitis

1998 • 27 citations

IL-13 over-expression in skin is not confined to IgE-mediated skin inflammation

1997 • 25 citations

Evaluation of mite allergen-induced Th1 and Th2 cytokine secretion of peripheral blood mononuclear cells from atopic dermatitis patients: association between IL-13 and mite-specific IgE levels

2001 • 24 citations

Identification of four novel interleukin-13 gene polymorphisms

2000 • 18 citations

A novel polymorphism in the human interleukin‐13 (IL‐13) promoter

2000 • 11 citations