Overexpression of nerve growth factor and basic fibroblast growth factor in AIDS dementia complex

Trophic factors and neuronal survival

1989 • 1,631 citations

Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

1993 • 1,436 citations

Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca²⁺ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

1995 • 616 citations

Evidence of neuronal oxidative damage in Alzheimer's disease.

1996 • 602 citations

Cytokine expression in the brain during the acquired immunodeficiency syndrome

1992 • 572 citations

Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dememtia

1993 • 418 citations

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

1994 • 402 citations

Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ

1993 • 355 citations

Oxidative stress and antioxidant therapy in Parkinson's disease

1996 • 342 citations

Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75 ngfr , TrkA, TrkB, and TrkC) in the adult human peripheral nervous system and nonneural tissues

1996 • 271 citations

Neurotrophic factor therapy for nervous system degenerative diseases

1994 • 254 citations

Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease

1993 • 234 citations

Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor

1995 • 214 citations

Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons

1993 • 198 citations

Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist.

1996 • 174 citations

Basic FGF attenuates amyloid β-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons

1997 • 162 citations

Regulation by Interleukin‐1 of Nerve Growth Factor Secretion and Nerve Growth Factor mRNA Expression in Rat Primary Astroglial Cultures

1991 • 153 citations

Therapeutic potential of neurotrophic factors for neurological disorders

1996 • 143 citations

AIDS Dementia Is Associated with Massive, Activated HIV-1 Infection and Concomitant Expression of Several Cytokines

1996 • 128 citations

Mechanisms of Neurotrophic Factor Protection against Calcium- and Free Radical-Mediated Excitotoxic Injury: Implications for Treating Neurodegenerative Disorders

1993 • 121 citations

Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease.

1997 • 113 citations

Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex

1995 • 113 citations

Induction of basic Fibroblast Growth Factor in Alzheimerʼs disease pathology

1990 • 112 citations

Free radicals induce gene expression of NGF and bFGF in rat astrocyte culture

1992 • 79 citations

Glutamate induces the growth factors NGF, bFGF, the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture

1993 • 79 citations

Mechanism of nerve growth factor mRNA regulation by interleukin-1 and basic fibroblast growth factor in primary cultures of rat astrocytes.

1991 • 78 citations

Co-expression of mRNA for Neurotrophic Factors in Human Neurons and Glial Cells in Culture

1994 • 77 citations

Tumor necrosis factor-α, microglia and astrocytes in AIDS dementia complex

1997 • 74 citations

Cytokine circuits in brain. Implications for AIDS dementia complex.

1994 • 73 citations

Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease

1995 • 72 citations

NGF attenuates 3-nitrotyrosine formation in a 3-NP model of Huntingtonʼs disease

1996 • 60 citations

Neuropathogenesis of acquired immunodeficiency syndrome dementia

1997 • 46 citations

bFGF and FGFR-3 immunoreactivity in the rat brain following systemic kainic acid administration at convulsant doses: localization of bFGF and FGFR-3 in reactive astrocytes, and FGFR-3 in reactive microglia

1997 • 46 citations

Cellular aspects of HIV-1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV-1 encephalitis

1997 • 32 citations

Inhibition of inducible nitric oxide synthase mRNA expression by basic fibroblast growth factor in human microglial cells

1995 • 31 citations

A continuing enigma: the role of cells of macrophage lineage in the development of HIV disease

1997 • 29 citations

Development of effective therapy for Alzheimer's disease based on neurotrophic factors

1994 • 28 citations

Neurotrophic factors in memory disorders

1994 • 26 citations

Expression of basic fibroblast growth factor, nerve growth factor, platelet-derived growth factor and transforming growth factor-? in human brain abscess

1994 • 24 citations

Development of Neurotrophic Factor Therapy for Alzheimer's Disease

2007 • 10 citations