Anergic T cells act as suppressor cellsin vitro andin vivo

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

CD4+CD25+ T Cells Inhibit Both the Induction and Effector Function of Autoreactive T Cells and Represent a Unique Lineage of Immunoregulatory Cells

1998 • 893 citations

"Infectious" Transplantation Tolerance

1993 • 890 citations

Oral tolerance: immune mechanisms and treatment of autoimmune diseases

1997 • 757 citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

Anergic T Cells as Suppressor Cells in Vitro

1994 • 389 citations

Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody.

1990 • 360 citations

The Th1/Th2 paradigm and the allograft response

1996 • 262 citations

Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay.

1990 • 247 citations

T cell suppression in transplantation tolerance through linked recognition.

1996 • 246 citations

Interleukin 10 Secretion and Impaired Effector Function of Major Histocompatibility Complex Class II–restricted T Cells Anergized In Vivo

1998 • 225 citations

IL-2 knockout recipient mice reject islet cell allografts.

1995 • 204 citations

Mechanisms of Peripheral Tolerance and Suppression Induced by Monoclonal Antibodies to CD4 and CD8

1996 • 195 citations

T Cell-Mediated Maintenance of Natural Self-Tolerance: its Breakdown as a Possible Cause of Various Autoimmune Diseases

1996 • 175 citations

Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation.

1995 • 171 citations

ARE Th2 HELPER T LYMPHOCYTES BENEFICIAL, DELETERIOUS, OR IRRELEVANT IN PROMOTING ALLOGRAFT SURVIVAL?1

1997 • 170 citations

Abnormal migration of T lymphocyte clones.

1982 • 153 citations

ENHANCED TYPE 2 AND DIMINISHED TYPE 1 CYTOKINES IN NEONATAL TOLERANCE

1995 • 148 citations

Rejection of H-Y Disparate Skin Grafts by Monospecific CD4+ Th1 and Th2 Cells: No Requirement for CD8+ T Cells or B Cells

1998 • 146 citations

T cell regulation in adult transplantation tolerance.

1996 • 144 citations

IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection. Evidence against a dominant protective role for T helper 2 cytokines in alloimmunity.

1996 • 135 citations

Mechanisms of Transplantation Tolerance

1994 • 135 citations

Blocking the CD28-B7 T cell costimulation pathway induces long term cardiac allograft acceptance in the absence of IL-4.

1997 • 129 citations

Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients.

1997 • 119 citations

Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells.

1990 • 117 citations

ACUTE REJECTION OF VASCULARIZED HEART ALLOGRAFTS IN THE ABSENCE OF IFN??1,2

1996 • 112 citations

Anergic T cells effect linked suppression

1997 • 87 citations

Aspartate at position 57 of nonobese diabetic I-Ag7 beta-chain diminishes the spontaneous incidence of insulin-dependent diabetes mellitus.

1995 • 85 citations

Prolonged islet allograft acceptance in the absence of interleukin 4 expression

1996 • 59 citations

Immobilized anti-CD3 mAb induces anergy in murine naive and memory CD4+ T cells in vitro

1997 • 55 citations

The in vivo behavior of T cell clones: altered migration due to loss of the lymphocyte surface homing receptor.

1985 • 53 citations

IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection.

1997 • 42 citations

A role for Th2 cytokines in the suppression of CD8⁺ T cell‐mediated graft rejection

1997 • 39 citations

Adoptive transfer of a T_h2-like cell line prolongs MHC class II antigen disparate skin allograft survival in the mouse

1994 • 36 citations

T-cell receptor expressed on an autoreactive T-cell clone, clone 4

1985 • 28 citations

A theoretical framework for self-tolerance and its relevance to therapy of autoimmune disease

1988 • 23 citations

MHC class II Ab diabetogenic residue 57 Asp/non-Asp dimorphism influences T-cell recognition and selection

1998 • 17 citations

Immunochemistry and molecular immunology

1996 • 15 citations