Retinoic acid receptors and retinoid X receptor-alpha down-regulate the transforming growth factor-beta 1 promoter by antagonizing AP-1 activity.
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References (33)
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
1987 • 3,057 citations
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
1986 • 2,499 citations
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
1988 • 2,380 citations
A human retinoic acid receptor which belongs to the family of nuclear receptors
1987 • 2,245 citations
Identification of a receptor for the morphogen retinoic acid
1987 • 2,007 citations
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
1990 • 1,605 citations
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
1990 • 1,583 citations
Nuclear receptor that identifies a novel retinoic acid response pathway
1990 • 1,529 citations
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
1992 • 1,514 citations
Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck
1990 • 1,375 citations
Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element
1990 • 1,326 citations
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
1990 • 1,272 citations
RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements
1991 • 1,241 citations
Nuclear receptors enhance our understanding of transcription regulation
1988 • 1,062 citations
Identification of a second human retinoic acid receptor
1988 • 1,049 citations
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
1992 • 966 citations
Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.
1988 • 604 citations
Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters
1988 • 597 citations
Prevention of Skin Cancer in Xeroderma Pigmentosum with the Use of Oral Isotretinoin
1988 • 578 citations
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.
1986 • 559 citations
Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential.
1990 • 398 citations
H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element.
1989 • 306 citations
Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro.
1992 • 242 citations
Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.
1990 • 229 citations
ELEVATED EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA AND PROTEOGLYCAN PRODUCTION IN EXPERIMENTAL GLOMERULONEPHRITIS
1990 • 196 citations
Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper
1991 • 177 citations
Identification of a novel isoform of the retinoic acid receptor gamma expressed in the mouse embryo.
1990 • 162 citations
Increased secretion of type beta transforming growth factor accompanies viral transformation of cells.
1985 • 132 citations
Interactions between retinoids and TGF βs in mouse morphogenesis
1992 • 124 citations
Expression of TGF-beta gene in adult T cell leukemia
1988 • 122 citations
Elevated Transforming Growth Factor-β 1 and β3 mRNA Levels are Associated withras+myc-induced Carcinomas in Reconstituted Mouse Prostate: Evidence for a Paracrine Role during Progression
1991 • 62 citations
Transforming growth factor beta 1 in liver carcinogenesis: messenger RNA expression and growth effects.
1990 • 50 citations
Effects of TGF‐βs in the Liver: Cell Proliferation and Fibrogenesis
2007 • 40 citations