The bactericidal effects of the respiratory burst and the myeloperoxidase system isolated in neutrophil cytoplasts

[136] Assay of catalases and peroxidases

1955 • 4,049 citations

Studies on the chlorinating activity of myeloperoxidase.

1976 • 918 citations

Cyclic guanosine monophosphate as a mediator of vasodilation.

1986 • 811 citations

Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection

1969 • 697 citations

IODINATION OF BACTERIA: A BACTERICIDAL MECHANISM

1967 • 621 citations

The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

1981 • 429 citations

Long-Lived Oxidants Generated by Human Neutrophils: Characterization and Bioactivity

1983 • 396 citations

Myeloperoxidase of the leucocyte of normal human blood. I. Content and localization

1962 • 392 citations

Chemiluminescence and superoxide production by myeloperoxidase-deficient leukocytes.

1976 • 373 citations

INHIBITION OF ERYTHROCYTE PSEUDOPEROXIDASE ACTIVITY BY TREATMENT WITH HYDROGEN PEROXIDE FOLLOWING METHANOL

1972 • 370 citations

Myeloperoxidase: Contribution to the Microbicidal Activity of Intact Leukocytes

1970 • 345 citations

Absence of both cytochrome b−245 subunits from neutrophils in X-linked chronic granulomatous disease

1987 • 324 citations

Myeloperoxidase-dependent effect of amines on functions of isolated neutrophils.

1983 • 257 citations

Myeloperoxidase, hydrogen peroxide, chloride antimicrobial system: nitrogen-chlorine derivatives of bacterial components in bactericidal action against Escherichia coli

1979 • 251 citations

Myeloperoxidase Deficiency

1981 • 246 citations

Functional activity of enucleated human polymorphonuclear leukocytes.

1983 • 230 citations

Isolation and properties of human neutrophil myeloperoxidase

1981 • 156 citations

Generation of nitrogen-chlorine oxidants by human phagocytes.

1984 • 156 citations

Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride

1985 • 153 citations

Guinea pig heterophil and eosinophil peroxidase

1972 • 142 citations

Defective Bactericidal Activity in Myeloperoxidase-deficient Human Neutrophils

1969 • 139 citations

Functional Aspects of a Second Mechanism of Candidacidal Activity by Human Neutrophils

1972 • 116 citations

Myeloperoxidase modulates the phagocytic activity of polymorphonuclear neutrophil leukocytes. Studies with cells from a myeloperoxidase-deficient patient.

1984 • 114 citations

Kinetics of oxygen consumption by phagocytosing human neutrophils

1978 • 103 citations

Role for Endogenous and Acquired Peroxidase in the Toxoplasmacidal Activity of Murine and Human Mononuclear Phagocytes

1982 • 93 citations

Studies on rat eosinophil peroxidase

1965 • 89 citations

Myeloperoxidase-Mediated Iodination by Granulocytes INTRACELLULAR SITE OF OPERATION AND SOME REGULATING FACTORS

1974 • 86 citations

Regulation of the oxidative response of human granulocytes to chemoattractants. No evidence for stimulated traffic of redox enzymes between endo and plasma membranes.

1985 • 85 citations

Neutrophils autoinactivate secretory products by myeloperoxidase- catalyzed oxidation

1985 • 73 citations

T. cruzi: sensitization to macrophage killing by eosinophil peroxidase.

1982 • 59 citations

Arming of mononuclear phagocytes by eosinophil peroxidase bound to Staphylococcus aureus.

1982 • 59 citations

Enhanced Killing of Myeloperoxidase-Coated Bacteria in the Myeloperoxidase-H2O2-C1- System

1978 • 58 citations

Human eosinophilic peroxidase: Biochemical characterization

1978 • 58 citations

The Effects of Ascorbic Acid on Bactericidal Mechanisms of Neutrophils

1971 • 52 citations

The estimation of serum lysozyme: A comparison of four assay methods

1977 • 43 citations

Increased respiratory burst in myeloperoxidase-deficient monocytes

1983 • 41 citations

Evidence for and partial characterization of three major and three minor chromatographic forms of human neutrophil myeloperoxidase

1986 • 41 citations

Iodination by stimulated human neutrophils. Studies on its stoichiometry, subcellular localization and relevance to microbial killing

1983 • 40 citations

Oxidative mechanisms utilized by human neutrophils to destroy Escherichia coli

1984 • 39 citations

Formation of HCN by human phagocytosing neutrophils — 1. Chlorination of Staphylococcus epidermidis as a source of HCN

1985 • 35 citations

Subcellular distribution of glycosidases in human polymorphonuclear leucocytes

1978 • 33 citations

Expression of specific granule markers on the cell surface of neutrophil cytoplasts

1986 • 31 citations

The development of cytochrome b-245 in maturing human macrophages

1986 • 29 citations

Functional integrity of cytokineplasts: specific chemotactic and capping responses.

1985 • 17 citations

Rapid covalent coupling of proteins to cell surfaces: Immunological characterization of viable protein-cell conjugates

1984 • 14 citations

Granules are necessary for death of neutrophils after phagocytosis of crystalline monosodium urate

1985 • 6 citations

Cellular cytotoxicity mediated by granule-depleted neutrophil cytoplasts

1985 • 5 citations

Oxidative Damage to Lysosomal Enzymes in Human Phagocytosing Neutrophils

1982 • 5 citations