Granules are necessary for death of neutrophils after phagocytosis of crystalline monosodium urate

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Separation of leukocytes from blood and bone marrow

1968 • 2,787 citations

Effects of cytochalasin B on polymorphonuclear leucocyte locomotion, phagocytosis and glycolysis

1972 • 258 citations

Functional activity of enucleated human polymorphonuclear leukocytes.

1983 • 230 citations

Clinical Science

1962 • 225 citations

QUANTITATIVE STUDIES OF PHAGOCYTOSIS

1973 • 210 citations

Leukocytic proteases and the immunologic release of lysosomal enzymes.

1972 • 197 citations

Cytochalasin B reversibly inhibits phagocytosis: functional, metabolic, and ultrastructural effects in human blood leukocytes and rabbit alveolar macrophages.

1971 • 187 citations

Molecular Basis of Gouty Inflammation: Interaction of Monosodium Urate Crystals with Lysosomes and Liposomes

1972 • 161 citations

THE MOBILIZATION AND EXTRACELLULAR RELEASE OF GRANULAR ENZYMES FROM HUMAN LEUKOCYTES DURING PHAGOCYTOSIS

1972 • 144 citations

Degranulation, membrane addition, and shape change during chemotactic factor-induced aggregation of human neutrophils.

1982 • 132 citations

Iodination by human polymorphonuclear leukocytes: a re-evaluation.

1977 • 131 citations

Superoxide anion generation by human neutrophils exposed to monosodium urate. effect of protein adsorption and complement activation

1982 • 104 citations

DIFFERENTIAL MEMBRANOLYTIC EFFECTS OF MICROCRYSTALLINE SODIUM URATE AND CALCIUM PYROPHOSPHATE DIHYDRATE

1971 • 95 citations

The inhibition of phagocytosis and facilitation of exocytosis in rabbit polymorphonuclear leukocytes by cytochalasin B.

1973 • 92 citations

A comparison of the duration of local anti-inflammatory effect of several adrenocorticosteroid esters--a bioassay technique.

1963 • 88 citations

Mg2+-ATPase as a membrane ecto-enzyme of human granulocytes. Inhibitors, activators and response to phagocytosis

1978 • 84 citations

Psychology on a Behaviourist Basis

1972 • 80 citations

Dissociation of intracellular lysosomal rupture from the cell death caused by silica

1980 • 69 citations

Complement as a mediator of inflammation in acute gouty arthritis. I. Studies on the reaction between human serum complement and sodium urate crystals.

1973 • 68 citations

Immunoglobulin G independent activation of the classical complement pathway by monosodium urate crystals.

1979 • 65 citations

Mechanisms of lysosomal enzyme release from leukocytes

1975 • 64 citations

Granulocytes without degranulation: neutrophil function in granule-depleted cytoplasts.

1983 • 62 citations

C3 Activation by Monosodium Urate Monohydrate and Other Crystalline Material

1979 • 61 citations

PHAGOCYTOSIS OF URATE CRYSTALS IN GOUTY SYNOVIAL FLUID

1962 • 58 citations

Polymorphonuclear leukocyte responses to monosodium urate crystals: modification by adsorbed serum proteins.

1979 • 52 citations

Activation of the alternative pathway of complement by monosodium urate crystals

1983 • 38 citations

Molecular orientation of immunoglobulin G adsorbed to microcrystalline monosodium urate monohydrate.

1980 • 34 citations

Hageman Factor and Acute Gouty Arthritis

1968 • 29 citations

Mechanisms of cellular interaction with monosodium urate crystals. igg‐dependent and igg‐independent platelet stimulation by urate crystals

1978 • 22 citations