EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses

Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

2000 • 918 citations

Multiple Sclerosis and Chronic Autoimmune Encephalomyelitis

2000 • 907 citations

Acute axonal injury in multiple sclerosis: Correlation with demyelination and inflammation

2000 • 889 citations

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

2001 • 864 citations

Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time

2002 • 766 citations

A Pathogenic Role for Myelin-Specific Cd8+ T Cells in a Model for Multiple Sclerosis

2001 • 650 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases

2002 • 471 citations

Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences

2001 • 470 citations

Myelin Antigen-Specific CD8+ T Cells Are Encephalitogenic and Produce Severe Disease in C57BL/6 Mice

2001 • 437 citations

CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

2002 • 395 citations

Natural Killer T Cell Activation Protects Mice Against Experimental Autoimmune Encephalomyelitis

2001 • 390 citations

Axon pathology in neurological disease: a neglected therapeutic target

2002 • 386 citations

Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

1997 • 360 citations

Less Mortality but More Relapses in Experimental Allergic Encephalomyelitis in CD8 ^-/- Mice

1992 • 359 citations

Role of CD8 ⁺ T Cells in Murine Experimental Allergic Encephalomyelitis

1992 • 351 citations

Activation of Natural Killer T Cells Potentiates or Prevents Experimental Autoimmune Encephalomyelitis

2001 • 294 citations

Animal models for autoimmune demyelinating disorders of the nervous system

2000 • 287 citations

Major Histocompatibility Complex (MHC) Class I Gene Expression in Single Neurons of the Central Nervous System: Differential Regulation by Interferon (IFN)-γ and Tumor Necrosis Factor (TNF)-α

1997 • 284 citations

Axon Loss in the Spinal Cord Determines Permanent Neurological Disability in an Animal Model of Multiple Sclerosis

2002 • 276 citations

Transection of Major Histocompatibility Complex Class I-Induced Neurites by Cytotoxic T Lymphocytes

2001 • 265 citations

Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients

2002 • 246 citations

The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat

1995 • 231 citations

Induction of oral tolerance to myelin basic protein in CD8-depleted mice: both CD4+ and CD8+ cells mediate active suppression.

1995 • 222 citations

Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1

1999 • 201 citations

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

1998 • 198 citations

MHC Class I-Restricted Lysis of Human Oligodendrocytes by Myelin Basic Protein Peptide-Specific CD8 T Lymphocytes

1998 • 162 citations

Role of natural killer cells and TCRγ δ T cells in acute autoimmune encephalomyelitis

1998 • 159 citations

Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides.

1994 • 157 citations

Theiler's virus infection of beta 2-microglobulin-deficient mice

1993 • 141 citations

Cutting Edge: Vα14-Jα281 NKT Cells Naturally Regulate Experimental Autoimmune Encephalomyelitis in Nonobese Diabetic Mice

2002 • 138 citations

The regulatory role of natural killer cells in multiple sclerosis

2004 • 132 citations

CD8⁺T cells control the TH phenotype of MBP-reactive CD4⁺T cells in EAE mice

2001 • 124 citations

Cutting Edge: In Vitro-Generated Tolerogenic APC Induce CD8+ T Regulatory Cells That Can Suppress Ongoing Experimental Autoimmune Encephalomyelitis

2004 • 109 citations

In Vivo Expression of Major Histocompatibility Complex Molecules on Oligodendrocytes and Neurons during Viral Infection

2001 • 107 citations

Allergic encephalomyelitis: Preparation of the encephalitogenic basic protein from bovine brain

1970 • 105 citations

Cutting Edge: C3, a Key Component of Complement Activation, Is Not Required for the Development of Myelin Oligodendrocyte Glycoprotein Peptide-Induced Experimental Autoimmune Encephalomyelitis in Mice

2001 • 87 citations

Frequencies of Neuroantigen-Specific T Cells in the Central Nervous System Versus the Immune Periphery During the Course of Experimental Allergic Encephalomyelitis

2001 • 80 citations

A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination

2002 • 78 citations

CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology

2001 • 56 citations

Analysis of maturation states of rat bone marrow-derived dendritic cells using an improved culture technique

2002 • 52 citations

A combination of adoptive transfer and antigenic challenge induces consistent murine experimental autoimmune encephalomyelitis in C57BL/6 mice and other reputed resistant strains

1992 • 47 citations

Regulation of Experimental Autoimmune Encephalomyelitis in the C57BL/6J Mouse by NK1.1+, DX5+, αβ+ T Cells

2001 • 38 citations

Induction of myelin basic protein-specific experimental autoimmune encephalomyelitis in C57BL/6 mice: Mapping of T cell epitopes and T cell receptor V? gene segment usage

1996 • 33 citations

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