Theiler's virus infection of beta 2-microglobulin-deficient mice

Natural Cell-Mediated Immunity

1978 • 1,063 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination

1975 • 615 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

In vivo effects of anti-asialo GM1. I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice.

1981 • 424 citations

Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells.

1991 • 372 citations

Simultaneous in situ detection of viral RNA and antigens.

1984 • 179 citations

LCMV-Specific, Class II-Restricted Cytotoxic T Cells in β2-Microglobulin-Deficient Mice

1992 • 164 citations

Identification of Theiler's virus infected cells in the central nervous system of the mouse during demyelinating disease

1987 • 164 citations

Demyelination induced by Theiler's virus: influence of the H-2 haplotype.

1985 • 157 citations

OBSERVATIONS ON ENCEPHALOMYELITIS OF MICE (DA STRAIN)

1952 • 157 citations

The Effect of L3T4 T Cell Depletion on the Pathogenesis of Theiler's Murine Encephalomyelitis Virus Infection in CBA Mice

1987 • 155 citations

Theiler's virus persists in glial cells during demyelinating disease

1981 • 153 citations

Successful therapy of Theiler's virus-induced demyelination (DA strain) with monoclonal anti-Lyt-2 antibody.

1988 • 128 citations

Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease

1990 • 113 citations

Partial suppression of Theiler's virus‐induced demyelination in vivo by administration of monoclonal antibodies to immune‐response gene products (Ia antigens)

1986 • 104 citations

Cytotoxic T cells isolated from the central nervous systems of mice infected with Theiler's virus

1991 • 101 citations

Susceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus

1979 • 100 citations

Demyelinating lesions due to Theiler's virus are associated with ongoing central nervous system infection

1986 • 89 citations

The interaction of two groups of murine genes determines the persistence of Theiler's virus in the central nervous system

1992 • 87 citations

Contrasting effects of immunosuppression on Theiler's virus infection in mice

1977 • 64 citations

Survival of athymic (nu/nu) mice after Theiler's murine encephalomyelitis virus infection by passive administration of neutralizing monoclonal antibody

1989 • 60 citations

Theiler's virus infection induces a specific cytotoxic T lymphocyte response

1991 • 57 citations

Theiler's virus infection in nude mice: viral RNA in vascular endothelial cells

1988 • 54 citations

Role of the humoral immune response in resistance to Theiler's virus infection

1991 • 45 citations

Characterization of B lymphocytes present in the demyelinating lesions induced by Theiler's virus.

1989 • 43 citations

In vivo induction of H‐2K/D antigens by recombinant interferon‐γ

1986 • 41 citations

Immunologic aspects of Theiler's murine encephalomyelitis virus infection

1990 • 38 citations

Genetic determinants of the demyelinating disease caused by Theiler's virus

1991 • 15 citations