Active antitumor immunotherapy, with or without B7-mediated costimulation, increases tumor progression in an immunogenic murine T cell lymphoma model

Enhancement of Antitumor Immunity by CTLA-4 Blockade

1996 • 3,585 citations

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.

1995 • 2,090 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.

1994 • 681 citations

CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

1995 • 489 citations

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity.

1994 • 482 citations

CD28-B7 interactions in T-cell activation

1994 • 315 citations

Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules.

1993 • 274 citations

T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells.

1994 • 174 citations

Costimulation of tumor-reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma.

1994 • 145 citations

Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 costimulatory molecules.

1995 • 133 citations

Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti‐CD28 and anti‐CD2 monoclonal antibodies

1988 • 128 citations

Migration Patterns of Dendritic cells in the Mouse

1988 • 105 citations

Effector T‐Cell Induction and T‐Cell Memory versus Peripheral Deletion of T Cells

1993 • 87 citations

Association between MHC class I antigen expression and malignancy of murine T lymphoma variants.

1990 • 20 citations

Modulation of T‐cell responsiveness during Trypanosoma cruzi infection: analysis in different lymphoid compartments

1994 • 18 citations

Immune surveillance: Both CD3⁺ CD4⁺ and CD3⁺ CD8⁺ T cells control in vivo growth of P815 mastocytoma

1990 • 16 citations

Tumorigenicity of mouse T lymphoma cells is controlled by the level of major histocompatibility complex class I H-2Kk antigens

1994 • 15 citations

Metastasis of mouse T lymphoma cells is controlled by the level of major histocompatibility complex class I H‐2D^K antigens

1994 • 12 citations

Limited T cell antigen receptor repertoire in tumor-infiltrating lymphocyte and inhibition of experimental lung metastasis of murine melanoma by anti-TCR antibody.

1995 • 11 citations

Immunogenization of a murine T-cell lymphoma via transfection with interferon-gamma.

1995 • 10 citations