Phylometabonomic Patterns of Adaptation to High Fat Diet Feeding in Inbred Mice

Role of Insulin Resistance in Human Disease

1988 • 12,099 citations

Insulin signalling and the regulation of glucose and lipid metabolism

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Metabonomics: a platform for studying drug toxicity and gene function

2002 • 1,871 citations

The Collaborative Cross, a community resource for the genetic analysis of complex traits

2004 • 1,095 citations

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

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Orthogonal signal correction of near-infrared spectra

1998 • 1,038 citations

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

2006 • 1,019 citations

750 MHz 1H and 1H-13C NMR Spectroscopy of Human Blood Plasma

1995 • 1,004 citations

Pharmaco-metabonomic phenotyping and personalized drug treatment

2006 • 801 citations

Diabetes and Cardiovascular Disease: The “Common Soil” Hypothesis

1995 • 673 citations

The genetics of human obesity

2005 • 647 citations

Nutrigenomics: goals and strategies

2003 • 643 citations

Genome-wide genetic association of complex traits in heterogeneous stock mice

2006 • 579 citations

Evaluation of the Orthogonal Projection on Latent Structure Model Limitations Caused by Chemical Shift Variability and Improved Visualization of Biomarker Changes in ¹H NMR Spectroscopic Metabonomic Studies

2004 • 543 citations

Dietary obesity in nine inbred mouse strains

1992 • 487 citations

A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model

2007 • 459 citations

Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse

2000 • 423 citations

The influence of genetic background on the expression of the obese (ob) gene in the mouse

1973 • 387 citations

Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

2004 • 349 citations

Dietary fat, genetic predisposition, and obesity: lessons from animal models

1998 • 296 citations

In Silico Mapping of Complex Disease-Related Traits in Mice

2001 • 294 citations

A High-Resolution Single Nucleotide Polymorphism Genetic Map of the Mouse Genome

2006 • 279 citations

Variation in Type 2 Diabetes-Related Traits in Mouse Strains Susceptible to Diet-Induced Obesity

2003 • 277 citations

Mouse models of insulin resistance

2002 • 254 citations

Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse

2003 • 234 citations

Effects of Diet and Genetic Background on Sterol Regulatory Element-Binding Protein-1c, Stearoyl-CoA Desaturase 1, and the Development of the Metabolic Syndrome

2005 • 232 citations

Genetic and Environmental Effects on Complex Traits in Mice

2006 • 209 citations

Insulin Resistance, Insulin Response, and Obesity as Indicators of Metabolic Risk

2007 • 195 citations

Gene-diet interactions in obesity

2000 • 161 citations

Glucose Homeostasis and Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred Strains of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1

2004 • 151 citations

RETRACTED: Nicotinamide nucleotide transhydrogenase: A key role in insulin secretion

2006 • 146 citations

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

2007 • 145 citations

A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice

2006 • 114 citations

Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice

2007 • 105 citations

Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes

2005 • 94 citations

Mouse phenogenomics: The fast track to “systems metabolism”

2005 • 49 citations

Relationship between phospholipid transfer protein activity and HDL level and size among inbred mouse strains

1999 • 42 citations

A high-resolution multistrain haplotype analysis of laboratory mouse genome reveals three distinctive genetic variation patterns

2005 • 37 citations