Analysis of recombination in mammalian cells using SV40 and SV40-derived vectors

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Stable replication of plasmids derived from Epstein–Barr virus in various mammalian cells

1985 • 1,303 citations

Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination

1985 • 978 citations

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

1987 • 786 citations

High frequency targeting of genes to specific sites in the mammalian genome

1986 • 619 citations

RECOMBINATION DEFICIENT MUTANTS OF E. COLI AND OTHER BACTERIA

1973 • 568 citations

Model for Homologous Recombination During Transfer of DNA into Mouse L Cells: Role for DNA Ends in the Recombination Process

1984 • 457 citations

Patterns of Integration of DNA Microinjected into Cultured Mammalian Cells: Evidence for Homologous Recombination Between Injected Plasmid DNA Molecules

1982 • 417 citations

ENZYMES OF GENERAL RECOMBINATION

1987 • 333 citations

Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules.

1982 • 281 citations

Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA.

1984 • 251 citations

The minimum amount of homology required for homologous recombination in mammalian cells.

1984 • 250 citations

Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene

1986 • 236 citations

Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process.

1984 • 227 citations

Homology Requirement for Efficient Gene Conversion Between Duplicated Chromosomal Sequences in Mammalian Cells

1987 • 207 citations

Direct and indirect gene replacements in Aspergillus nidulans.

1985 • 183 citations

Joining of nonhomologous DNA double strand breaksin vitro

1988 • 166 citations

Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences.

1985 • 165 citations

Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei.

1985 • 120 citations

Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication.

1982 • 117 citations

Partial purification and characterization of a recombinase from human cells

1986 • 116 citations

The genetic analysis of recombination using adenovirus overlapping terminal DNA fragments

1983 • 114 citations

Homologous Recombination between Repeated Chromosomal Sequences in Mouse Cells

1984 • 114 citations

Homologous and nonhomologous recombination in monkey cells.

1983 • 114 citations

Homologous Recombination between Defective neo Genes in Mouse 3T6 Cells

1984 • 111 citations

Carcinogens can induce homologous recombination between duplicated chromosomal sequences in mouse L cells.

1988 • 111 citations

Properties of recombination-deficient mutants of bacteriophage lambda

1970 • 101 citations

High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes

1985 • 100 citations

Photographic detection of luminescence in Escherichia coli containing the gene for firefly luciferase

1987 • 95 citations

Effect of insertions, deletions, and double-strand breaks on homologous recombination in mouse L cells.

1985 • 94 citations

Recombination events after transient infection and stable integration of DNA into mouse cells.

1985 • 89 citations

Recombination between temperature-sensitive mutants of simian virus 40

1974 • 85 citations

Novel use of synthetic oligonucleotide insertion mutants for the study of homologous recombination in mammalian cells.

1983 • 80 citations

Intramolecular recombination of linear DNA catalyzed by the Escherichia coli RecE recombination system

1985 • 73 citations

Genetic demonstration of mitotic recombination in cultured chinese hamster cell hybrids

1984 • 69 citations

Simian virus 40 recombinants are produced at high frequency during infection with genetically mixed oligomeric DNA.

1979 • 68 citations

Double-strand gap repair results in homologous recombination in mouse L cells.

1986 • 67 citations

Analysis of gene expression using Simian Virus 40 vectors

1983 • 63 citations

Homologous recombination catalyzed by human cell extracts.

1985 • 61 citations

Rapid assay for extrachromosomal homologous recombination in monkey cells.

1985 • 55 citations

Homologous Recombination with DNA Introduced into Mammalian Cells

1984 • 54 citations

Characterization of an ATP-dependent DNA strand transferase from human cells.

1987 • 54 citations

Analysis of recombination in mammalian cells using SV4O genome segments having homologous overlapping termini

1980 • 50 citations

Does simian virus 40 DNA integrate into cellular DNA during productive infection?

1978 • 50 citations

Information transfer between duplicated chromosomal sequences in mammalian cells involves contiguous regions of DNA.

1986 • 49 citations

Genetic recombination of Herpes simplex virus, the role of the host cell and UV-irradiation of the virus

1980 • 47 citations

The kinetics of adenovirus recombination in homotypic and heterotypic genetic crosses

1980 • 42 citations

Extrachromosomal and chromosomal gene conversion in mammalian cells.

1986 • 41 citations

Fate of mismatched base-pair regions in polyoma heteroduplex DNA during infection of mouse cells.

1976 • 40 citations

Homologous recombination intermediates between two duplex DNA catalysed by human cell extracts

1987 • 36 citations

Homologous Recombination in Mouse L Cells

1984 • 31 citations

Visualization of genetic recombination intermediates of human adenovirus type 2 DNA from infected HeLa cells

1980 • 28 citations

The Recombination and Integration of DNAs Introduced into Mouse L Cells

1984 • 26 citations

Mitotic recombination between homologous chromosomes generates H-2 somatic cell variants in vitro.

1987 • 25 citations

Recombination Between Endogenous and Exogenous Simian Virus 40 Genes. II. Biochemical Evidence for Genetic Exchange

1977 • 22 citations

Homologous recombination between a defective virus and a chromosomal sequence in mammalian cells.

1985 • 22 citations

Gene transfer and gene therapy

1988 • 21 citations

Recombination between endogenous and exogenous simian virus 40 genes III. Rescue of SV40 tsA and tsBC mutants by passage in permissive transformed monkey lines

1980 • 21 citations

Promotion of double-strand break repair by human nuclear extracts preferentially involves recombination with intact homologous DNA

1987 • 20 citations

Rescue of chromosomal T-antigen sequences onto extrachromosomally replicating, defective simian virus 40 DNA by homologous recombination.

1986 • 16 citations

Correction of deletions in mammalian cells by gene conversion

1987 • 8 citations

Mutation of Autonomously Replicating Plasmids

1986 • 6 citations