Fluorescence ratio measurements of double‐labeled probes for multiple in situ hybridization by digital imaging microscopy

Flow Cytometry and Sorting

1991 • 669 citations

Cloning of human satellite III DNA: different components are on different chromosomes

1979 • 470 citations

In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors

1988 • 462 citations

Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy.

1992 • 385 citations

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

1986 • 380 citations

Detection of bcr - abl Fusion in Chronic Myelogeneous Leukemia by in Situ Hybridization

1990 • 371 citations

The Use of a Charge-Coupled Device for Quantitative Optical Microscopy of Biological Structures

1987 • 302 citations

Multiple fluorescence in situ hybridization

1990 • 267 citations

Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes.

1988 • 231 citations

Cyanine dye labeling reagents for sulfhydryl groups

1989 • 223 citations

Three‐color fluorescence in situ hybridization for the simultaneous detection of multiple nucleic acid sequences

1989 • 219 citations

Detection of the Philadelphia chromosome in interphase nuclei

1990 • 185 citations

Rapid interphase and metaphase assessment of specific chromosomal changes in neuroectodermal tumor cells by in situ hybridization with chemically modified DNA probes

1988 • 177 citations

Chapter 16 Solid-State Imagers for Microscopy

1988 • 117 citations

Measuring and manipulating cytosolic Ca2+ with trapped indicators

1984 • 116 citations

Novel non-isotopic in situ hybridization technique detects small (1 Kb) unique sequences in routinely G-banded human chromosomes: fine mapping of N-myc and β-NGF genes

1987 • 112 citations

Direct visualization of single copy genes on banded metaphase chromosomes by nonisotopicin situhybridization

1988 • 110 citations

Detection of chromosome aberrations in interphase tumor nuclei by nonradioactive in situ hybridization

1989 • 110 citations

Interphase cytogenetics of brain tumors

1991 • 104 citations

Aminomethyl coumarin acetic acid: A new fluorescent labelling agent for proteins

1986 • 102 citations

Low-level image processing by max-min filters

1988 • 85 citations

Modification of cytidine residues with a bisulfite-O-methylhydroxylamine mixture.

1974 • 74 citations

The gene encoding human protective protein (PPGB) is on chromosome 20

1991 • 73 citations

Modification of cytidine residues with a bisulfite— mixture

1974 • 56 citations

Quantification of fluorescence in situ hybridization signals by image cytometry

1992 • 43 citations

The Origins of Modern Fluorescence Microscopy and Fluorescent Probes

1989 • 37 citations

Quantification of inter‐ and intra‐nuclear variation of fluorescence in situ hybridization signals

1992 • 29 citations

High‐performance optical filters for fluorescence analysis

1988 • 16 citations