The role of stem cell factor in mobilization of peripheral blood progenitor cells: Synergy with G‐CSF

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 846 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 634 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages.

1991 • 454 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

Recombinant human stem cell factor enhances the formation of colonies by CD34+ and CD34+lin- cells, and the generation of colony-forming cell progeny from CD34+lin- cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor

1991 • 341 citations

The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7.

1991 • 222 citations

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells

1991 • 202 citations

Expression of the YB5.B8 antigen (c-kit proto-oncogene product) in normal human bone marrow

1991 • 195 citations

Isolation of c-kit receptor-expressing cells from bone marrow, peripheral blood, and fetal liver: functional properties and composite antigenic profile

1991 • 188 citations

The effects on hematopoiesis of recombinant stem cell factor (ligand for c-kit) administered in vivo to mice either alone or in combination with granulocyte colony-stimulating factor

1991 • 169 citations

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

1991 • 157 citations

Tissue transplantation as an analytic and therapeutic tool in hereditary anemias

1970 • 145 citations

Effect of c-kit ligand on in vitro human megakaryocytopoiesis

1991 • 140 citations

Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates

1991 • 133 citations

Radioprotection of mice by recombinant rat stem cell factor.

1992 • 129 citations

Recombinant rat stem cell factor synergizes with recombinant human granulocyte colony-stimulating factor in vivo in mice to mobilize peripheral blood progenitor cells that have enhanced repopulating potential

1993 • 126 citations

STEEL, A NEW DOMINANT GENE IN THE HOUSE MOUSE

1956 • 102 citations

TWO HEREDITARY MOUSE ANEMIAS (Sl/Sl^d and W/W^v) DEFICIENT IN RESPONSE TO ERYTHROPOIETIN*

1968 • 98 citations

Recombinant rat stem cell factor stimulates the amplification and differentiation of fractionated mouse stem cell populations

1992 • 75 citations

Proof of whole-cell implant in therapy of W-series anemia

1968 • 70 citations

Implantation of Normal Blood-Forming Tissue in Radiated Genetically Anemic Hosts

1956 • 66 citations

Genetic analysis of the dominant white-spotting (W) region on mouse chromosome 5: identification of cloned DNA markers near W.

1988 • 62 citations

Hematologic effects of stem cell factor in vivo and in vitro in rodents

1991 • 60 citations

Giant granules of beige mice. A quantitative marker for granulocytes in bone marrow transplantation.

1973 • 59 citations

ANALYSIS OF PLEIOTROPISM AT THE W-LOCUS IN THE MOUSE: RELATIONSHIP BETWEEN THE EFFECTS OF W AND Wv SUBSTITUTION ON HAIR PIGMENTATION AND ON ERYTHROCYTES

1949 • 57 citations

Abnormalities of Megakaryocytes in W/Wv Mice

1973 • 52 citations

Abnormalities of Megakaryocytes in Sl/Sld Mice

1973 • 50 citations

Reduced Blood and Marrow Neutrophils and Granulocytic Colony-Forming Cells in Sl/Sld Mice

1976 • 40 citations

Analysis of the hematopoietic effects of new dominant spotting (W) mutations of the mouse. II. Effects on mast cell development.

1983 • 28 citations