Aldosterone Blockade Attenuates Urinary Monocyte Chemoattractant Protein-1 and Oxidative Stress in Patients with Type 2 Diabetes Complicated by Diabetic Nephropathy

p22 Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells

1996 • 768 citations

Aldosterone-Induced Inflammation in the Rat Heart

2002 • 564 citations

Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats

2003 • 517 citations

Isoprostanes: Potential Markers of Oxidant Stress in Atherothrombotic Disease

1997 • 461 citations

Aldosterone: A Mediator of Myocardial Necrosis and Renal Arteriopathy*

2000 • 459 citations

Spironolactone Improves Angiotensin-Induced Vascular Changes and Oxidative Stress

2002 • 397 citations

Angiotensin II Induces Monocyte Chemoattractant Protein-1 Gene Expression in Rat Vascular Smooth Muscle Cells

1998 • 388 citations

Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy

2000 • 337 citations

Possible Contributions of Reactive Oxygen Species and Mitogen-Activated Protein Kinase to Renal Injury in Aldosterone/Salt-Induced Hypertensive Rats

2004 • 305 citations

Increased Formation of Distinct F ₂ Isoprostanes in Hypercholesterolemia

1998 • 276 citations

Aldosterone Administration to Mice Stimulates Macrophage NADPH Oxidase and Increases Atherosclerosis Development

2004 • 239 citations

The role of angiotensin II in diabetic nephropathy: Emphasis on nonhemodynamic mechanisms

1997 • 232 citations

?Escape? of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: Implications for therapy

1995 • 206 citations

ACE Inhibitors Improve Diabetic Nephropathy Through Suppression of Renal MCP-1

2003 • 179 citations

Chemokines and renal disease

1997 • 163 citations

The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: a randomized controlled study

2004 • 145 citations

Local Overexpression of Monocyte Chemoattractant Protein-1 at Vessel Wall Induces Infiltration of Macrophages and Formation of Atherosclerotic Lesion

2002 • 141 citations

F2-Isoprostane excretion rate and diurnal variation in human urine

1999 • 94 citations

The Renin-Angiotensin System in Diabetic Nephropathy

2001 • 15 citations