Decreased transforming growth factor‐(β) response and binding in insulin‐independent teratoma‐derived cell lines with increased tumorigenic properties

In Vitro Cultivation of Human Tumors: Establishment of Cell Lines Derived From a Series of Solid Tumors2

1973 • 2,213 citations

Selection of Successive Tumour Lines for Metastasis

1973 • 1,360 citations

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.

1988 • 962 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Distribution and modulation of the cellular receptor for transforming growth factor-beta.

1987 • 556 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

A new type of transforming growth factor-beta, TGF-beta 3.

1988 • 396 citations

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

1987 • 387 citations

Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts.

1985 • 364 citations

Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta.

1989 • 346 citations

Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines.

1985 • 344 citations

Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms

1990 • 342 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

HORMONE-PRODUCING CULTURES OF ADRENAL AND PITUITARY TUMOR ORIGIN

1962 • 285 citations

Transforming Growth Factor β: Biochemistry and Roles in Embryogenesis, Tissue Repair and Remodeling, and Carcinogenesis

1988 • 255 citations

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.

1987 • 222 citations

Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies.

1984 • 207 citations

Selection and Biologic Properties of Malignant Variants of a Murine Lymphosarcoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 138 citations

Regulatory effects of cell density on the binding of transforming growth factor beta, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor.

1988 • 120 citations

Membrane binding characteristics of two forms of transforming growth factor-beta.

1987 • 118 citations

Latent beta-transforming growth factor in nontransformed and Kirsten sarcoma virus-transformed normal rat kidney cells, clone 49F.

1984 • 112 citations

Preparation and binding of radioactively labeled porcine transforming growth factor type β

1986 • 71 citations

An in vitro model to study adipose differentiation in serum-free medium

1982 • 65 citations

Tumorigenicity associated with loss of differentiation and of response to insulin in the adipogenic cell line 1246

1985 • 29 citations

Autocrine growth induced by the insulin-related factor in the insulin-independent teratoma cell line 1246-3A.

1988 • 20 citations

Characterization of transforming growth factors produced by the insulin‐independent teratoma‐derived cell line 1246‐3A

1989 • 13 citations

Purification of an insulin-related factor secreted by a teratoma-derived mesodermal cell line.

1987 • 11 citations

Characterization of an insulin-related factor secreted by a teratoma cell line

1986 • 11 citations

Identification of insulin receptors on the insulin‐independent variant 1246‐3A cell line

1988 • 3 citations