A mutation in segment I-S6 alters slow inactivation of sodium channels

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Structure and Function of Voltage-Sensitive Ion Channels

1988 • 1,171 citations

Molecular Determinants of State-Dependent Block of Na ⁺ Channels by Local Anesthetics

1994 • 829 citations

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.

1992 • 810 citations

Two types of inactivation in Shaker K+ channels: Effects of alterations in the carboxy-terminal region

1991 • 688 citations

A reinterpretation of mammalian sodium channel gating based on single channel recording

1983 • 675 citations

Molecular Basis of Charge Movement in Voltage-Gated Sodium Channels

1996 • 603 citations

Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels.

1993 • 582 citations

Auxiliary subunits of voltage-gated ion channels

1994 • 561 citations

Primary structure and functional expression of a mammalian skeletal muscle sodium channel

1989 • 561 citations

Putative receptor for the cytoplasmic inactivation gate in the Shaker K+ channel

1991 • 341 citations

Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells.

1991 • 328 citations

Structural Elements Involved in Specific K+ Channel Functions

1992 • 268 citations

Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance.

1978 • 263 citations

Functional expression of sodium channel mutations identified in families with periodic paralysis

1993 • 226 citations

Molecular determinants of voltage-dependent inactivation in calcium channels

1994 • 217 citations

Distribution and kinetics of membrane dielectric polarization. 1. Long-term inactivation of gating currents.

1982 • 183 citations

Impaired slow inactivation in mutant sodium channels

1996 • 179 citations

External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels.

1996 • 132 citations

A mutation in segment IVS6 disrupts fast inactivation of sodium channels.

1994 • 122 citations

Sodium channel gating in clonal pituitary cells. The inactivation step is not voltage dependent.

1989 • 118 citations

Slow changes in membrane permeability and long‐lasting action potentials in axons perfused with fluoride solutions

1970 • 115 citations

Voltage-dependent ion channels and their gating

1992 • 90 citations

Steady-state availability of sodium channels. Interactions between activation and slow inactivation

1992 • 69 citations

Inactivation in Myxicola giant axons responsible for slow and accumulative adaptation phenomena.

1981 • 49 citations

Cysteines in the Shaker K+ channel are not essential for channel activity or zinc modulation

1994 • 37 citations

Slow inactivation of muscle μ1 Na+ channels in permanently transfected mammalian cells

1996 • 10 citations