Endothelium-dependent relaxation resistant to NG-nitro-l-arginine in rat aorta

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

Role of endothelium in responses of vascular smooth muscle.

1983 • 1,975 citations

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

1990 • 1,869 citations

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1988 • 1,379 citations

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

1985 • 1,266 citations

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

1987 • 1,182 citations

Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide

1990 • 996 citations

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

1983 • 949 citations

Endothelium‐dependent hyperpolarization of canine coronary smooth muscle

1988 • 785 citations

<scp>l</scp>‐N^G‐nitro arginine (<scp>l</scp>‐NOARG), a novel, <scp>l</scp>‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro

1990 • 769 citations

Acetylcholine releases endothelium‐derived hyperpolarizing factor and EDRF from rat blood vessels

1988 • 702 citations

The regeneration of aortic endothelium

1958 • 374 citations

Endothelium-derived hyperpolarizing a new endogenous inhibitor from the vascular endothelium

1988 • 369 citations

Endothelial Cells as Mediators of Vasodilation of Arteries

1984 • 322 citations

Nω-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation

1990 • 310 citations

Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats.

1992 • 253 citations

Hyperpolarization as a mechanism for endothelium‐dependent relaxations in the porcine coronary artery.

1992 • 210 citations

Some electrical properties of the endothelium‐dependent hyperpolarization recorded from rat arterial smooth muscle cells.

1989 • 209 citations

Nitric oxide, ACh, and electrical and mechanical properties of canine arterial smooth muscle

1988 • 162 citations

Differential effects of substrate depletion on drug-induced contractions of rabbit aorta

1970 • 157 citations

Endothelium‐dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim

1988 • 138 citations

Different activation of L-arginine pathway by bradykinin, serotonin, and clonidine in coronary arteries

1990 • 109 citations

Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses

1991 • 97 citations

Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release.

1991 • 84 citations

Neither Nitric Oxide nor Nitroglycerin Accounts for All the Characteristics of Endothelially Mediated Vasodilatation of Pig Coronary Arteries

1988 • 82 citations

NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein.

1990 • 68 citations

Endothelium‐dependent relaxation and hyperpolarization of canine coronary artery smooth muscles in relation to the electrogenic Na‐K pump

1989 • 53 citations

Electrophysiological and mechanical effects of substance P and acetylcholine on rabbit aorta.

1988 • 49 citations

Purinergic relaxation and hyperpolarization in guinea pig and rabbit coronary artery: role of the endothelium.

1992 • 49 citations

Canine arteries release two different endothelium-derived relaxing factors

1989 • 44 citations

Differences in the K⁺‐channels opened by cromakalim, acetylcholine and substance P in rat aorta and porcine coronary artery

1991 • 38 citations

Effect of ACh on electrical and mechanical activity in guinea pig coronary arteries

1989 • 33 citations

Potassium ions potentiate the muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex slices: A comparison of neonatal and adult rats

1990 • 17 citations

NW-Nitro L-arginine benzyl ester, a potent irreversible inhibitor of endothelium dependent relaxation

1991 • 15 citations