Allelic loss on chromosome 18q as a prognostic marker in stage II colorectal cancer

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

Levamisole and Fluorouracil for Adjuvant Therapy of Resected Colon Carcinoma

1990 • 2,226 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

A second-generation linkage map of the human genome

1992 • 1,721 citations

Allelotype of Colorectal Carcinomas

1989 • 1,333 citations

Fluorouracil plus Levamisole as Effective Adjuvant Therapy after Resection of Stage III Colon Carcinoma: A Final Report

1995 • 907 citations

MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma

1996 • 855 citations

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1995 • 824 citations

Allelic Loss of Chromosome 18q and Prognosis in Colorectal Cancer

1994 • 708 citations

Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of levamisole and the combination of levamisole and fluorouracil. The North Central Cancer Treatment Group and the Mayo Clinic.

1989 • 694 citations

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

1994 • 496 citations

Intergroup study of fluorouracil plus levamisole as adjuvant therapy for stage II/Dukes' B2 colon cancer.

1995 • 373 citations

Association of p53 mutations with short survival in colorectal cancer

1994 • 357 citations

Allelic Loss in Colorectal Carcinoma

1989 • 338 citations

Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

1995 • 308 citations

Mad-related genes in the human

1996 • 308 citations

The DCC Protein and Prognosis in Colorectal Cancer

1996 • 307 citations

MULTIPLE GENETIC ALTERATIONS IN DISTAL AND PROXIMAL COLORECTAL CANCER

1989 • 306 citations

Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]

1989 • 273 citations

Survival and acquired genetic alterations in colorectal cancer

1992 • 208 citations

The Prognostic Significance of Tumor Location and Bowel Obstruction in Dukes B and C Colorectal Cancer

1983 • 176 citations

Concerted Nonsyntenic Allelic Loss in Human Colorectal Carcinoma

1988 • 147 citations

The Genetic Basis of Cancer

1995 • 140 citations

Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas.

1993 • 139 citations

Determination of Tumor Aggressiveness in Colorectal Cancer by K-ras-2 Analysis

1993 • 107 citations

Prognostic factors in colorectal cancer

1992 • 107 citations

Survival and acquired genetic alterations in colorectal cancer

1992 • 100 citations

Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.

1995 • 90 citations

Loss of expression of the DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis and non-familial adenomatous polyposis patients.

1992 • 87 citations

Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis.

1994 • 81 citations

Cell adhesion molecules as tumour suppressors

1993 • 78 citations

Current status of adjuvant chemotherapy for colorectal cancer: Can molecular markers play a role in predicting prognosis?

1992 • 78 citations

Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder

1994 • 75 citations

PCR-based microsatellite polymorphisms in the detection of loss of heterozygosity in fresh and archival tumour tissue

1993 • 68 citations

Current status of adjuvant chemotherapy for colorectal cancer: Can molecular markers play a role in predicting prognosis?

1992 • 54 citations

Molecular Genetic Studies of Tumor suppressor Gene Regions on chromosomes 13 and 17 in Colorectal Tumors

1992 • 53 citations

Gastrointestinal cancers : biology, diagnosis, and therapy

1995 • 49 citations

A Rapid and Simple Procedure for the Routine Detection of ras Point Mutations in Formalin-Fixed, Paraffin-Embedded Tissues

1992 • 44 citations

The deleted in colon cancer (DCC) gene is consistently expressed in colorectal cancers and metastases.

1996 • 37 citations

Prognosis in colorectal cancer.

1988 • 5 citations