Implication of RNA structure on antisense oligonucleotide hybridization kinetics

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Improved predictions of secondary structures for RNA.

1989 • 822 citations

Comparative Anatomy of 16-S-like Ribosomal RNA

1985 • 689 citations

Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms.

1991 • 468 citations

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

1990 • 280 citations

Substrate sequence effects on "hammerhead" RNA catalytic efficiency.

1990 • 238 citations

RNA bulges and the helical periodicity of double-stranded RNA

1990 • 163 citations

Nucleotide Sequence Analysis of the T24 Human Bladder Carcinoma Oncogene

1983 • 137 citations

Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.

1990 • 132 citations

Sequence-specific DNA purification by triplex affinity capture.

1992 • 131 citations

Complementary oligonucleotide binding to transfer RNA

1972 • 128 citations

Contributions of dangling end stacking and terminal base-pair formation to the stabilities of XGGCCp, XCCGGp, XGGCCYp, and XCCGGYp helixes

1985 • 122 citations

Gel electrophoresis assays for DNA-protein interactions.

1989 • 117 citations

Prevention of chain cleavage in the chemical synthesis of 2′-silylated oligoribonucleotides

1989 • 94 citations

Rapid renaturation of complementary DNA strands mediated by cationic detergents: a role for high-probability binding domains in enhancing the kinetics of molecular assembly processes.

1991 • 93 citations

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site

1990 • 93 citations

Walking along human c-myc mRNA with antisense oligodeoxynucleotides: maximum efficacy at the 5' cap region.

1991 • 89 citations

A novel effect of EGF on mRNA stability

1988 • 59 citations

Secondary structure of prokaryotic 5S ribosomal ribonucleic acids: a study with ribonucleases

1981 • 55 citations

The kinetics of codon-anticodon interaction in yeast phenylalanine transfer RNA

1975 • 53 citations

Effects of single-base bulges on intercalator binding to small RNA and DNA hairpins and a ribosomal RNA fragment

1989 • 43 citations

Binding of complementary oligoribonucleotides to yeast initiator transfer RNA

1975 • 43 citations

Complementary Oligonucleotide Probe of Vesicular Stomatitus Virus Matrix Protein mRNA Translation

1986 • 34 citations

RecA protein-promoted homologous pairing and strand exchange between intact and partially single-stranded duplex DNA

1992 • 27 citations

A study on the alkylsilyl groups in oligoribonucleotide synthesis

1990 • 19 citations