Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.

CRC Handbook of Chemistry and Physics

2014 • 56,288 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Improved Estimation of Secondary Structure in Ribonucleic Acids

1973 • 2,302 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Linked Functions and Reciprocal Effects in Hemoglobin: A Second Look

1964 • 1,613 citations

Improved free-energy parameters for predictions of RNA duplex stability.

1986 • 1,472 citations

The Chemistry of Self-Splicing RNA and RNA Enzymes

1987 • 523 citations

Comparison of fungal mitochondrial introns reveals extensive homologies in RNA secondary structure

1982 • 501 citations

Making ends meet: a model for RNA splicing in fungal mitochondria

1982 • 459 citations

Electrophoretic characterization of bacterial polyribosomes in agarose-acrylamide composite gels

1969 • 433 citations

Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysis

1975 • 433 citations

The guanosine binding site of the Tetrahymena ribozyme

1989 • 356 citations

A crystallographic study of metal-binding to yeast phenylalanine transfer RNA

1977 • 322 citations

Control of cole 1 plasmid replication: The process of binding of RNA I to the primer transcript

1984 • 298 citations

The Tetrahymena ribozyme acts like an RNA restriction endonuclease

1986 • 285 citations

Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes

1988 • 251 citations

Gel retardation at low pH resolves trp repressor-DNA complexes for quantitative study.

1988 • 227 citations

RNA - ligand interactions:(I) magnesium binding sites in yeast tRNA^Phe

1977 • 221 citations

One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity

1986 • 211 citations

Double Helical DNA: Conformations, Physical Properties, and Interactions with Ligands

1981 • 201 citations

Thermodynamic extent of counterion release upon binding oligolysines to single-stranded nucleic acids.

1990 • 190 citations

Laser temperature-jump, spectroscopic, and thermodynamic study of salt effects on duplex formation by dGCATGC

1989 • 163 citations

Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme

1989 • 139 citations

DNA cleavage catalysed by the ribozyme from Tetrahymena

1990 • 130 citations

Control of replication of plasmid R1: kinetics of in vitro interaction between the antisense RNA, CopA, and its target, CopT.

1988 • 118 citations

An RNA mutation that increases the affinity of an RNA–protein interaction

1987 • 116 citations

Enhancement of terbium(III) and europium(III) fluorescence in complexes with Escherichia coli tRNA

1974 • 90 citations

Free energy contributions of G.cntdot.U and other terminal mismatches to helix stability

1986 • 84 citations

Reversibility of cyclization of the tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice

1985 • 63 citations

Effects of substrate structure on the kinetics of circle opening reactions of the self-splicing intervening sequence fromTetrahymena thermophila: evidence for substrate and Mg²⁺binding lnteractions

1989 • 61 citations

Kinetics for reaction of a circularized intervening sequence with CU, UCU, CUCU, and CUCUCU: mechanistic implications from the dependence on temperature and on oligomer and magnesium concentrations

1988 • 56 citations

An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme

1990 • 55 citations