A novel disruption of cortical development inp35?/? mice distinct fromreeler

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse

1961 • 1,488 citations

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1994 • 915 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

1995 • 882 citations

Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

1997 • 727 citations

Neuronal position in the developing brain is regulated by mouse disabled-1

1997 • 698 citations

The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall

1995 • 662 citations

The Subplate, A Transient Neocortical Structure: Its Role in the Development of Connections between Thalamus and Cortex

1994 • 642 citations

Scrambler and yotari disrupt the disabled gene and produce a reeler -like phenotype in mice

1997 • 637 citations

Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography

1982 • 629 citations

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.

1996 • 592 citations

A brain-specific activator of cyclin-dependent kinase 5

1994 • 575 citations

Requirement for subplate neurons in the formation of thalamocortical connections

1990 • 560 citations

Two new mutants, ‘trembler’ and ‘reeler’, with neurological actions in the house mouse (Mus musculus L.)

1951 • 517 citations

Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody

1997 • 512 citations

Dual origin of the mammalian neocortex and evolution of the cortical plate

1978 • 503 citations

Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system

1993 • 453 citations

The reeler gene encodes a protein with an EGF–like motif expressed by pioneer neurons

1995 • 347 citations

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

1997 • 337 citations

Cortical development: View from neurological mutants two decades later

1995 • 284 citations

Aberrant Splicing of a Mouse disabled Homolog, mdab1, in the scrambler Mouse

1997 • 263 citations

Changes in the distribution of extracellular matrix components accompany early morphogenetic events of mammalian cortical development

1991 • 251 citations

Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice

1984 • 250 citations

Involvement of Subplate Neurons in the Formation of Ocular Dominance Columns

1992 • 250 citations

BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone

1992 • 241 citations

Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axonogenesis is revealed through dosage-sensitive interactions with disabled

1989 • 240 citations

Neocortical Development

1992 • 228 citations

Early ontogeny of the secondary proliferative population of the embryonic murine cerebral wall

1995 • 212 citations

Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain

1974 • 186 citations

Cerebellar Disorganization Characteristic of Reeler in Scrambler Mutant Mice Despite Presence of Reelin

1997 • 161 citations

Determinants of cell shape and orientation: A comparative Golgi analysis of cell‐axon interrelationships in the developing neocortex of normal and reeler mice

1979 • 159 citations

Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration

1996 • 154 citations

Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain

1994 • 147 citations

Abnormal reorganization of preplate neurons and their associated extracellular matrix: An early manifestation of altered neocortical development in the reeler mutant mouse

1997 • 140 citations

Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate.

1993 • 123 citations

Chondroitin sulfate proteoglycans in the developing cerebral cortex: The distribution of neurocan distinguishes forming afferent and efferent axonal pathways

1995 • 116 citations

Birthdate and Cell Marker Analysis of Scrambler: A Novel Mutation Affecting Cortical Development with a Reeler-Like Phenotype

1997 • 114 citations

Development of cairetinin immunoreactivity in the neocortex of the rat

1995 • 108 citations

Localization of calretinin in cells of layer I (Cajal-Retzius cells) of the developing cortex of the rat

1994 • 91 citations

Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse.

1997 • 79 citations

Cortical development: Layers of complexity

1997 • 59 citations