The Difference in the Binding of Phosphatidylinositol Distinguishes MAP2 from MAP2C and Tau

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

Theoretical aspects of DNA-protein interactions: Co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice

1974 • 2,905 citations

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1989 • 2,308 citations

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

1990 • 849 citations

Tau protein binds to microtubules through a flexible array of distributed weak sites.

1991 • 540 citations

Light and electron microscopic studies of the distribution of microtubule‐associated protein 2 in rat brain: A difference between dendritic and axonal cytoskeletons

1984 • 424 citations

Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence

1984 • 378 citations

Differential subcellular localization of tubulin and the microtubule- associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies

1984 • 346 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family.

1989 • 306 citations

Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro.

1993 • 219 citations

Equilibrium of the actin-tropomyosin interaction

1979 • 194 citations

Microtubule bundling by tau proteins in vivo: analysis of functional domains.

1992 • 186 citations

Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters

1986 • 184 citations

Neuronal microtubule‐associated proteins in the embryonic avian spinal cord

1988 • 167 citations

Two Separate 18-Amino Acid Domains of Tau Promote the Polymerization of Tubulin

1989 • 167 citations

The tubulin-binding sequence of brain microtubule-associated proteins, tau and MAP-2, is also involved in actin binding

1990 • 137 citations

Microtubule-associated proteins and neuronal morphogenesis

1991 • 136 citations

Molecular cloning of a ubiquitously distributed microtubule-associated protein with Mr 190,000.

1990 • 122 citations

Embryonic MAP2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP2

1989 • 118 citations

Phosphorylation of Microtubule-Associated Proteins (MAPs) and pH of the Medium Control Interaction between MAPs and Actin Filaments1

1981 • 117 citations

The multiple phosphorylation of the microtubule-associated protein MAP2 controls the MAP2: tubulin interaction

1984 • 112 citations

Molecular structure of microtubule-associated protein 2b and 2c from rat brain.

1990 • 111 citations

Functional analyses of the domain structure of microtubule-associated protein-4 (MAP-U)

1991 • 100 citations

The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptide.

1989 • 98 citations

Calmodulin inhibits interaction of actin with MAP2 and Tau, two major microtubule-associated proteins.

1985 • 91 citations

Microassay for proteins on nitrocellulose filter using protein dye-staining procedure

1985 • 84 citations

Effect of various hepatic membrane fractions on microtubule assembly-with special emphasis on the role of membrane phospholipids.

1981 • 51 citations

Peptides corresponding to the second repeated sequence in MAP-2 inhibit binding of microtubule-associated proteins to microtubules

1990 • 42 citations

Quantification of proteins in the low nanogram range by staining with the colloidal gold stain AuroDye

1987 • 41 citations

Analysis of the microtubule-binding domain of MAP-2.

1985 • 41 citations

The mechanism of equilibrium binding of microtubule-associated protein 2 to microtubules. Binding is a multi-phasic process and exhibits positive cooperativity

1993 • 39 citations

Microtubule-Associated Protein Interactions with Actin Filaments: Evidence for Differential Behavior of Neuronal MAP-2 and Tau in the Presence of Phosphatidylinositol

1993 • 34 citations

Modulation of microtubule assembly and stability by phosphatidylinositol action on microtubule-associated protein-2.

1987 • 31 citations

Nucleosidediphosphate Kinase Associates with Rings but not with Assembled Microtubules

1981 • 28 citations

Microtubule‐associated protein autophosphorylation alters in vitro microtubule dynamic instability

1992 • 25 citations

Reduction in Microtubule Dynamics In Vitro by Brain Microtubule-Associated Proteins and by a Microtubule-Associated Protein-2 Second Repeated Sequence Analogue

1993 • 21 citations

Phosphatidylinositol inhibits microtubule assembly by binding to microtubule-associated protein 2 at a single, specific, high-affinity site

1992 • 17 citations

Chemically synthesized 182–235 segment of tau protein and analogue peptides are efficient in vitro microtubule assembly inducers of low apparent sequence specificity

1992 • 9 citations