Identification of Regulatory and Catalytic Domains in the Apoptosis Nuclease DFF40/CAD

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

Caspases: the executioners of apoptosis

1997 • 4,674 citations

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1998 • 3,169 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

1997 • 1,848 citations

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1998 • 1,651 citations

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1998 • 534 citations

Bcl-X _L interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1998 • 534 citations

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

1997 • 316 citations

CIDE, a novel family of cell death activators with homology to the 45kDa subunit of the DNA fragmentation factor

1998 • 315 citations

ICE-LAP6, a Novel Member of the ICE/Ced-3 Gene Family, Is Activated by the Cytotoxic T Cell Protease Granzyme B

1996 • 304 citations

CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45

1998 • 194 citations

Molecular cloning and characterization of human caspase-activated DNase

1998 • 174 citations