Encapsulated genetically engineered fibroblasts: Release of nerve growth factor and effects in vivo on recovery of cholinergic markers after devascularizing cortical lesions

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

A rapid radiochemical method for the determination of choline acetyltransferase

1975 • 2,406 citations

Nerve growth factor.

1968 • 2,025 citations

Alginate as immobilization matrix for cells

1990 • 1,846 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1986 • 1,458 citations

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

1986 • 1,063 citations

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

1987 • 1,031 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Grafting Genetically Modified Cells to the Damaged Brain: Restorative Effects of NGF Expression

1988 • 508 citations

Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases

1989 • 470 citations

An Enzyme‐Linked Immunoassay for Nerve Growth Factor (NGF): A Tool for Studying Regulatory Mechanisms Involved in NGF Production in Brain and in Peripheral Tissues

1987 • 377 citations

Mechanisms of action of intracerebral neural implants: studies on nigral and striatal grafts to the lesioned striatum

1987 • 348 citations

Optimization of microencapsulation parameters: Semipermeable microcapsules as a bioartificial pancreas

1985 • 336 citations

Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system—I. Forebrain

1990 • 224 citations

Grafting genetically modified cells to the brain: Possibilities for the future

1987 • 206 citations

Gangliosides potentiate in vivo and in vitro effects of nerve growth factor on central cholinergic neurons.

1989 • 204 citations

Nerve growth factor (NGF) reverses axotomy-induced decreases in choline acetyltransferase, NGF receptor and size of medial septum cholinergic neurons

1989 • 197 citations

Nerve growth factor-induced synaptogenesis and hypertrophy of cortical cholinergic terminals.

1992 • 166 citations

Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats

1992 • 162 citations

Intracerebral implantation of nerve growth factor-producing fibroblasts protects striatum against neurotoxic levels of excitatory amino acids

1991 • 157 citations

Prospects of transplantation in human neurodegenerative diseases

1991 • 132 citations

Sustained Release of Nerve Growth Factor from Biodegradable Polymer Microspheres

1992 • 120 citations

Quantitative immunocytochemistry using an image analyzer. I. Hardware evaluation, image processing, and data analysis

1988 • 116 citations

The effect of capsule composition on the biocompatibility of alginate-poly-1-lysine capsules

1991 • 105 citations

Effect of Unilateral Decortication on Choline Acetyltransferase Activity in the Nucleus Basalis and Other Areas of the Rat Brain

1985 • 91 citations

Cholinergic grafts, memory and ageing

1991 • 70 citations

Transplantation of Polymer Encapsulated Neurotransmitter Secreting Cells: Effect of the Encapsulation Technique

1991 • 59 citations

Autocrine Differentiation of PC12 Cells Mediated by Retroviral Vectors

1990 • 29 citations

Microencapsulation of genetically engineered fibroblasts secreting nerve growth factor

1993 • 27 citations

Neuronal replacement by intracerebral neural implants in animal models of neurodegenerative disease.

1988 • 24 citations

Combining CNS transplantation and gene transfer

1989 • 21 citations

Transient responses of continuously growing yeast cultures to dilution rate shifts: A sensitive means to analyze biology and the performance of equipment

1986 • 15 citations

Functional Analysis of Neural Grafts in the Neostriatum

1990 • 15 citations

Microencapsulation of human cells: Its effects on growth of normal and tumour cells in vitro

1991 • 10 citations

Delivery of Nerve Growth Factor Within the Rat Brain Using Genetically Modified Cells

1992 • 1 citations