Fenfluramine

The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity

1968 • 587 citations

Characteristics of the Human Lymphocyte Insulin Receptor

1973 • 320 citations

[Obesity and diabetes].

1958 • 264 citations

The genetic contribution to coronary heart disease through lipoprotein concentrations.

1975 • 246 citations

Follow-up Study of Physical Growth of Children Who Had Excessive Weight Gain in First Six Months of Life

1970 • 241 citations

Comparison of continuous and intermittent anorectic therapy in obesity.

1968 • 211 citations

Action of fenfluramine on monoamine stores of rat tissues

1971 • 185 citations

Infantile Overnutrition among Artificially Fed Infants in the Sheffield Region

1971 • 162 citations

The effects of selective lesioning of brain serotonin or catecholamine containing neurones on the anorectic activity of fenfluramine and amphetamine

1972 • 143 citations

On the in vivo and in vitro actions of fenfluramine and its derivatives on central monoamine neurons, especially 5-hydroxytryptamine neurons, and their relation to the anorectic activity of fenfluramine.

1975 • 122 citations

Drugs and sleep.

1968 • 118 citations

Central action of anorexic agents: Effects of amphetamine and fenfluramine in rats with lateral hypothalamic lesions

1974 • 86 citations

Fenfluramine: evidence for a neurotoxic action on midbrain and a long-term depletion of serotonin.

1975 • 86 citations

The effect of 5-hydroxytryptophan on food intake and on the anorexic action of amphetamine and fenfluramine

1975 • 85 citations

Fenfluramine: Amphetamine Congener That Fails to Maintain Drug-Taking Behavior in the Rhesus Monkey

1974 • 82 citations

Role of monoamines in the anorexigenic actions of fenfluramine, amphetamine and p-chloromethamphetamine

1974 • 77 citations

Treatment of refractory obesity with fenfluramine.

1966 • 75 citations

Drugs of Dependence Though Not of Abuse: Fenfluramine and Imipramine

1971 • 70 citations

Obesity and Its Management.

1974 • 70 citations

Structure-activity relations in psychotomimetic phenylalkylamines

1974 • 69 citations

[Pharmacology and biochemistry of fenfluramine].

1973 • 66 citations

5,6-dihydroxytryptamine: Suppression of the anorexigenic action of fenfluramine

1973 • 65 citations

Fenfluramine Metabolism

1968 • 64 citations

FENFLURAMINE AND MUSCLE GLUCOSE UPTAKE IN MAN

1968 • 64 citations

A comparison of the effects of fenfluramine and amphetamine on uptake release and catabolism of norepinephrine in rat brain.

1972 • 62 citations

Role of catecholamines in the anorectic effects of amphetamine in rats

1974 • 61 citations

Comparison of anorexigenic and behavioral potency of phenylethylamines.

1972 • 61 citations

Obesity: Its Pathogenesis And Management

1975 • 55 citations

Chronic Fenfluramine Administration: Some Cerebral Effects

1971 • 55 citations

Hypoglycemic Action of Fenfluramine in Diabetes Mellitus

1973 • 55 citations

Withdrawal Depression in Obese Patients after Fenfluramine Treatment

1972 • 54 citations

Effects of two slimming drugs on sleep.

1968 • 52 citations

EFFECT OF DIET, SULPHONYLUREAS, AND PHENFORMIN ON PERIPHERAL GLUCOSE UPTAKE IN DIABETES AND OBESITY

1968 • 50 citations

Subjective Effects of Two Anorexigenic Agents Fenfluramine and AN 448 in Amphetamine‐Dependent Subjects

1972 • 49 citations

Methamphetamine, fenfluramine and their N-dealkylated metabolites: effect on monoamine concentrations in rat tissues.

1972 • 49 citations

Cholestyramine, clofibrate and nicotinic acid as single or combined treatment of type IIa and IIb hyperlipoproteinaemia.

1975 • 47 citations

Controlled trial of propranolol in intermittent claudication

1975 • 46 citations

EFFECT OF FENFLURAMINE ON BLOOD-LIPIDS IN MAN

1969 • 46 citations

Antagonism by methysergide of the 5-hydroxytryptamine-like action of toxic doses of fenfluramine in dogs

1970 • 43 citations

Some 5-hydroxytryptamine-like actions of fenfluramine: a comparison with (+)-amphetamine and diethylpropion

1971 • 40 citations

A comparative trial of different regimens of fenfluramine and phentermine in obesity.

1973 • 40 citations

Depression Following Fenfluramine Withdrawal

1972 • 39 citations

Central nervous system effects of fenfluramine hydrochloride.

1972 • 39 citations

Comparison of the time course of the anorectic effect of fenfluramine and amphetamine with drug levels in blood

1975 • 38 citations

The absorption and urinary excretion in man of fenfluramine and its main metabolite.

1967 • 38 citations

FENFLURAMINE OVERDOSAGE

1969 • 35 citations

Biphasic action of a 5-hydroxytryptamine inhibitor on fenfluramine-induced anorexia

1973 • 35 citations

Gas chromatographic measurement of levels of fenfluramine and norfenfluramine in human plasma red cells and urine following therapeutic doses

1970 • 34 citations

FENFLURAMINE IN THE TREATMENT OF OBESITY

1973 • 34 citations

COMPARISON OF FENFLURAMINE AND METFORMIN IN TREATMENT OF OBESITY

1970 • 33 citations

Tremors and tremorogenic agents

1972 • 33 citations

Dissociation of the anorexic effects of fenfluramine and amphetamine following intrahypothalamic injection

1973 • 32 citations

Plasma concentrations of fenfluramine and its metabolite, norfenfluramine, after single and repeated oral administration.

1971 • 30 citations

FENFLURAMINE IN OBESE PATIENTS ON VARIOUS ANTIHYPERTENSIVE DRUGS

1969 • 29 citations

EEG profiles of fenfluramine, amobarbital and dextroamphetamine in normal volunteers

1971 • 29 citations

Unusual effect of fenfluramine.

1969 • 28 citations

A CONTROLLED INVESTIGATION OF THE " GLYCOLYPTIC " ACTION OF FENFLURAMINE

1972 • 28 citations

Amphetamine analogues and brain amines

1972 • 28 citations

Fenfluramine and critical flicker frequency

1967 • 27 citations

Effects of fenfluramine on sleep-wakefulness in cats

1971 • 26 citations

The central hypotensive action of amphetamine, ephedrine, phentermine, chlorphentermine and fenfluramine

1972 • 25 citations

Fenfluramine (Ponderax) in the Treatment of Obese Psychiatric Out-patients

1969 • 25 citations

The Effect of Drugs on Lipogenesis from Glucose and Palmitate in Human Adipose Tissue

1971 • 24 citations

Cardiovascular and autonomic effects of fenfluramine hydrochloride

1965 • 24 citations

Appetite suppression and central nervous system stimulation in the rhesus monkey

1971 • 24 citations

Anorexigenic effects of fenfluramine hydrochloride in rats, guinea pigs, and dogs

1969 • 24 citations

Studies on the site of action of a new anorectic agent, fenfluramine.

1969 • 23 citations

FENFLURAMINE OVERDOSAGE

1969 • 23 citations

N-ethyl-α-methyl-α-(m-trifluoromethylbenzyl)nitron—the major in vitro metabolic product of fenfluramine in guinea-pig liver microsomal fractions

1973 • 23 citations

Pharmacokinetics of absorption, distribution and elimination of fenfluramine and its main metabolite in man

1972 • 23 citations

Sleep-waking patterns in cats after administration of fenfluramine and other monoaminergic modulating drugs

1973 • 22 citations

Norfenfluramine and serotonin turnover rate in the rat brain

1972 • 21 citations

A new sensitive gas-chromatographic method for the determination of fenfluramine in biological specimens

1972 • 21 citations

Toxicologic studies of fenfluramine

1971 • 21 citations

Effect of fenfluramine on the intestinal absorption of triglycerides

1973 • 21 citations

The effects of chronic fenfluramine administration on behaviour and body weight

1973 • 21 citations

The role of norfenfluramine in fenfluramine-induced mydriasis

1973 • 20 citations

Does fenfluramine act via norfenfluramine ?

1975 • 19 citations

Effect of Fenfluramine on Human Growth Hormone Release

1973 • 19 citations

Fenfluramine-induced ultrastructural alterations in tissues of rats and guinea pigs

1974 • 19 citations

Subjective effects of two anorexigenic agents--fenfluramine and AN 448 in normal subjects.

1975 • 18 citations

A clinical trial of fenfluramine in obese children.

1967 • 18 citations

The non-medical misuse of fenfluramine by drug-dependent young South Africans.

1975 • 18 citations

A comparative trial of fenfluramine and diethylpropion inbesity.

1970 • 18 citations

The effect of a low-calorie diet with and without fenfluramine on the glucose tolerance and insulin secretion of obese maturity-onset diabetics

1973 • 18 citations

Fenfluramine and norfenfluramine on glucose uptake into skeletal muscle.

1975 • 18 citations

A comparative study of the pharmacologic actions of amphetamine and fenfluramine.

1970 • 17 citations

A Preliminary Trial of Fenfluramine in General Practice

1965 • 16 citations

Fenfluramine Blockade of CNS Stimulant Effects of Amphetamines

1973 • 16 citations

Skin as a microhabitat

1975 • 16 citations

Effects of Caloric Restriction and Fenfluramine on Weight Loss and Personality Profiles of Patients with Long Standing Obesity

1973 • 16 citations

FENFLURAMINE OVERDOSAGE

1969 • 16 citations

A collaborative investigation of fenfluramine. Anorexigenic with sedative properties.

1970 • 16 citations

COMPARISON OF A NEW ANORECTIC AGENT AN 448 WITH FENFLURAMINE IN THE TREATMENT OF REFRACTORY OBESITY

1974 • 15 citations

Effects of amphetamine on neuronal activity in the hypothalamus

1969 • 15 citations

Stimulation by Fenfluramine of Glucose Uptake into Skeletal Muscle In Vitro

1974 • 15 citations

Fenfluramine overdosage.

1967 • 15 citations

A clinical trial of fenfluramine.

1965 • 15 citations

On the effect of anorectic drugs on striatum homovanillic acid in rats

1974 • 15 citations

The anorectic activity of fenfluramine.

1975 • 15 citations

A double-blind clinical trial of an appetite depressant, fenfluramine, in general practice.

1967 • 15 citations

Metabolic effects of fenfluramine--a double-blind study.

1975 • 15 citations

Effects of various anorexigenic agents on open field behavior of rats.

1973 • 14 citations

Time sampling of rat exploratory behaviour: A reliable screening test for the C.N.S. effects of anorexic agents

1974 • 14 citations

Abuse of fenfluramine.

1973 • 14 citations

Intermittent treatment with anorectic drugs.

1974 • 14 citations

Assessment of reinforcing properties of amphetamine analogues in self-administering rats.

1975 • 14 citations

Effect of Fenfluramine on Appetite and Lipid Metabolism of the Young Ruminant

1970 • 13 citations

The effect of fenfluramine on glucose tolerance, insulin, lipid and lipoprotein levels in patients with peripheral arterial disease

1972 • 13 citations

FENFLURAMINE IN MANIA

1973 • 12 citations

Human Autonomic Pharmacology XVI. Benzedrine Sulfate as an Aid in the Treatment of Obesity

1994 • 11 citations

Fenfluramine and triglyceride synthesis by microsomes of the intestinal mucosa in the rat.

1973 • 11 citations

A comparative trial of fenfluramine and diethylpropion in obese, hypertensive patients.

1971 • 11 citations

Fenfluramine and methylcellulose in the treatment of obesity: the relationship between plasma drug concentrations and therapeutic efficacy.

1975 • 11 citations

A double-blind evaluation of fenfluramine in anxious somatizing neurotic medical clinic patients.

1966 • 11 citations

The effects of acutely administered fenfluramine on activity and eating behaviour

1971 • 11 citations

Effect of fennfluramine on alcohol and saccharin consumption in the rat.

1972 • 11 citations

FENFLURAMINE IN THE TREATMENT OF OBESITY

1968 • 10 citations

Precipitating antibody in the sputum in chronic respiratory disease

1975 • 10 citations

The effect of dietary restriction and anorectic drugs on linear growth velocity in childhood obesity.

1975 • 10 citations

Fenfluramine and 780SE in experimental alcoholism in rats.

1975 • 10 citations

Effects of fenfluramine and related compounds on the synthesis of glycerolipids by rat liver.

1975 • 10 citations

The metabolic effects, and the composition of the tissue lost, in weight reduction by obese patients on treatment with fenfluramine

1973 • 10 citations

Effect of fenfluramine on the electrical activity of the hypothalamic feeding centers

1971 • 10 citations

Treatment of obesity with fenfluramine

1973 • 9 citations

Diazepam for fenfluramine intoxication.

1974 • 9 citations

The effect of acute administration of (meta trifluoro methyl‐phenyl)‐l‐(benzoyl oxy) ethyl amino‐2‐propane (780 SE) and fenfluramine on human sleep

1970 • 9 citations

Toxic and therapeutic effects of EMTP in obesity

1969 • 9 citations

Some cardiovascular and autonomic effects of fenfluramine hydrochloride.

1971 • 8 citations

Fenfluramine and growth hormone release.

1973 • 8 citations

Anti-amphetamine activity of fenfluramine and S 992 in the isolated tail artery of the rat

1969 • 8 citations

Behavioural and biochemical effects of fenfluramine in patients with neurologic disease.

1975 • 8 citations

The effect of a low-calorie diet with and without fenfluramine, and fenfluramine alone on the glucose tolerance and insulin secretion of overweight non-diabetics

1973 • 8 citations

A six month study of a carbohydrate restricted diet in the management of maturity-onset diabetes and an evaluation of fenfluramine in patients unresponsive to this diet.

1975 • 8 citations

The possible central stimulant mechanisms of some appetite suppressants.

1972 • 8 citations

Carbohydrate metabolism in obesity.

1946 • 8 citations

[Absorption, distribution and metabolism of fenfluramine].

1973 • 8 citations

The effect of fenfluramine on obesity and plasma lipids of patients with renal allografts.

1975 • 8 citations

Psychomotor Test Performance with a Fenfluramine-Amphetamine Combination

1974 • 8 citations

Unusual effect of fenfluramine.

1970 • 8 citations

Fenfluramine dependence.

1971 • 8 citations

Drugs and appetite.

1974 • 7 citations

Comparative effects of ten anorectic drugs on sleep-wakefulness patterns in cats

1971 • 7 citations

The inhibitory effect of fenfluramine on pancreatic lipase activity.

1971 • 7 citations

A trial of fenfluramine (PACaps) and diet in overweight diabetic patients.

1975 • 7 citations

Fenfluramine, a New Anorexigenic Agent

1971 • 7 citations

The effect of fenfluramine on insulin binding and on basal and insulin-stimulated oxidation of 1-14C-glucose by human adipose tissue.

1975 • 6 citations

The effect of fenfluramine and its derivatives on triglyceride secretion by the liver of the rabbit.

1975 • 6 citations

Proceedings: Effect of fenfluramine and norfenfluramine on glucose uptake by the isolated rat diaphragm.

1974 • 6 citations

Unusual effect of fenfluramine.

1970 • 6 citations

A clinical trial of a new fenfluramine preparation (Ponderax PA).

1975 • 6 citations

Hyperpyrexia and overdose.

1972 • 6 citations

The effects of fenfluramine on fixed ratio responding

1973 • 6 citations

Fenfluramine: study of its central action through its effects on sleep.

1969 • 6 citations

FENFLURAMINE AND DREAMING

1974 • 6 citations

ACTION OF FENFLURAMINE

1973 • 5 citations

Proceedings: Central stimulant action of fenfluramine in the rat.

1972 • 5 citations

Effect of Fenfluramine on the single neuron activities of the hypothalamic feeding centers

1972 • 5 citations

Species-dependent effects of fenfluramine on the central nervous system

1971 • 5 citations

[Study on the excretion, localization and metabolism of a new anorexigenic substance: fenfluramine].

1965 • 5 citations

Controlled Therapeutic Trials

1971 • 5 citations

[The influence of appetite depressants on carbohydrate and fatty acid metabolism].

1965 • 5 citations

[Comparative action of fenfluramine and amphetamine in rats with hypothalamic obesity].

1969 • 5 citations

Prolonged Action Fenfluramine Capsules versus Fenfluramine Tablets in General Practice

1975 • 5 citations

Review of general surgery 1974

1975 • 5 citations

A double-blind clinical trial of fenfluramine in the treatment of obesity.

1973 • 5 citations

A trial of fenfluramine in children with obesity associated with reduced muscle activity.

1972 • 5 citations

New group of anorexigenic compounds

1970 • 5 citations

Prolonged-action fenfluramine in non-diabetic patients with refractory obesity.

1975 • 5 citations

Hormonal and metabolic studies of the action of fenfluramine in normal man, obesity, acromegaly and diabetes mellitus.

1975 • 5 citations

A Short Trial for Fenfluramine in Alcoholism

1972 • 5 citations

APPETITE SUPPRESSANTS AND PULMONARY HYPERTENSION

1969 • 5 citations

FENFLURAMINE OVERDOSAGE

1969 • 5 citations

Prolonged action fenfluramine in general practice.

1975 • 4 citations

Bioavailability of prolonged action fenfluramine.

1975 • 4 citations

[The excretion of anorectic phenylalkylamines in the urine].

1966 • 4 citations

SEBUM EXCRETION RATE AND BIOCHEMISTRY IN PATIENTS WITH ACNE VULGARIS TREATED BY ORAL FENFLURAMINE

1971 • 4 citations

A double-blind clinical trial of fenfluramine.

1972 • 4 citations

Hodgkin’s disease of the duodenum presenting with haemorrhage and perforation

1975 • 4 citations

Fenfluramine in the management of obesity.

1973 • 4 citations

Comparison of fenfluramine (with ad libitum food intake) with 1,000 calorie diet in obesity.

1972 • 3 citations

Fenfluramine withdrawal and epilepsy.

1975 • 3 citations

Experimental evidence for imipramine like activity of fenfluramine.

1970 • 3 citations

Dangers of certain appetite suppressants.

1969 • 3 citations

Fenfluramine in obesity.

1970 • 3 citations

Fenfluramine in corticosteroid-induced obesity

1972 • 3 citations

The Management of Obesity

1972 • 3 citations

The effects of fenfluramine and 780SE on fat absorption.

1975 • 3 citations

[Insulin secretion and hydrocarbon tolerance in essential obesity in women (influence of fenfluramine, phenformin and D-amphetamine)].

1973 • 3 citations

Thermogenic properties of norfenfluramine

1971 • 3 citations

Addiction or dependence?

1971 • 2 citations

Some effects of fenfluramine and its derivatives on the central catecholaminergic systems of mice.

1975 • 2 citations

Plastics in pharmacy and medicine.

1971 • 2 citations

Addiction or Dependence?

1971 • 2 citations

Correlation between Bile Secretion and Triglyceride Release in Perfused Rat Liver and Some Effects of Fenfluramine

1972 • 2 citations

Psychometric studies on sleep for the evaluation of central effects of drugs. The effects of fenfluramine on sleep.

1969 • 2 citations

Gonadal dysgenesis, Turner's syndrome and phenotype in the South African Bantu.

1971 • 2 citations

DNA synthesis in adipose tissue.

1975 • 2 citations

The teaching of comprehensive medicine 1938-1969.

1971 • 2 citations

Comparative effects of four antiobesity agents on blood plasma lipids in man.

1972 • 2 citations

Fenfluramine overdosage in childhood. Case report.

1972 • 2 citations

Hypotensive effect of fenfluramine in the treatment of obesity.

1971 • 2 citations

Effect of long-term fenfluramine treatment on drug-metabolism in rat

1973 • 2 citations

A comparison of the efficacy and acceptability of fenfluramine tablets (BP) and prolonged action capsules.

1975 • 2 citations

Effect of fenfluramine and dexamphetamine on pyruvate kinase.

1971 • 2 citations

Proceedings: Effect of the (minus)- and (plus)-isomers of fenfluramine and norfenfluramine on glucose uptake by the isolated rat hemidiaphragm.

1974 • 2 citations

[Influence of fenfluramine on the weekly curve of weight loss during obesity].

1974 • 1 citations

[Progress in the surgical technic for the treatment of cervico-uterine cancer. Posterior pelvic approach].

1960 • 1 citations

Proceedings: The effect of norfenfluramine on thermoregulation in the rabbit.

1974 • 1 citations

[The use of anorexigenic drugs in the treatment of diabetes mellitus].

1963 • 1 citations

[Fenfluramine. Anorexigenic drug in obstetrical practice].

1969 • 1 citations

The role of advice in child psychiatry.

1971 • 1 citations

Effect of fenfluramine on certain enzymes and on skin and amniotic cells in tissue culture.

1975 • 1 citations

Fenfluramine in the treatment of psoriasis. A preliminary report.

1975 • 1 citations

Fenfluramine and pigmented naevi.

1972 • 1 citations

[Hypoglycemic action of fenfluramine in obese diabetics].

1971 • 1 citations

[Effects and indications of fenfluramine in the treatment of obesity].

1973 • 1 citations

[Side effects associated with prolonged use of fenfluramine].

1973 • 1 citations

PROLONGED TOTAL FASTING FOR OBESITY

1967 • 1 citations

A treatment for refractory obesity using fenfluramine without dietary restriction.

1970 • 1 citations

Circulatory effects of fenfluramine in obese hypertensive patients.

1974 • 1 citations

[Effects of fenfluramine-amphetamine combination on psychomotor activity].

1973 • 1 citations

FENFLURAMINE OVERDOSAGE

1970 • 1 citations

FENFLURAMINE OVERDOSAGE

1969 • 1 citations

[Effects of fenfluramine, administered on short or long-term basis, on lipolysis of obese subjects].

1973 • 1 citations

Drug-dependent south African national servicemen.

1973 • 1 citations

Influence of a long acting preparation of fenfluramine on body weight, body composition and skinfold thickness in obese subjects.

1975 • 1 citations

Obesity and diabetes.

1972 • 1 citations

Assessment of new formulation of fenfluramine in the management of the obese, diabetic African.

1975 • 1 citations

Effect of fenfluramine on steady state plasma levels of amitriptyline.

1975 • 1 citations

Deleted Work

1955 • 0 citations