Biochemical Studies on Mammalian Lipoxygenases^a,^b

Advances in prostaglandin, thromboxane, and leukotriene research

1985 • 759 citations

Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.

1986 • 311 citations

Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.

1984 • 292 citations

2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis

1982 • 251 citations

Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes. Activation by adenosine 5'-triphosphate.

1983 • 215 citations

Flavonoids: Potent inhibitors of arachidonate 5-lipoxygenase

1983 • 202 citations

Purification of arachidonate 5-lipoxygenase from porcine leukocytes and its reactivity with hydroperoxyeicosatetraenoic acids.

1986 • 191 citations

Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes.

1985 • 177 citations

Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase.

1986 • 171 citations

Arachidonate 12-lipoxygenase purified from porcine leukocytes by immunoaffinity chromatography and its reactivity with hydroperoxyeicosatetraenoic acids.

1986 • 168 citations

Lipoxin A. Stereochemistry and biosynthesis.

1986 • 162 citations

Arachidonate 12-lipoxygenase of porcine leukocyte with activity for 5-hydroxyeicosatetraenoic acid

1982 • 118 citations

A second pathway of leukotriene biosynthesis in porcine leukocytes.

1981 • 102 citations

On the stereochemistry and biosynthesis of lipoxin B.

1986 • 99 citations

Purification, characterization, and structural properties of a single protein from rat basophilic leukemia (RBL-1) cells possessing 5-lipoxygenase and leukotriene A4 synthetase activities.

1986 • 97 citations

Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes.

1983 • 93 citations

Metabolism of arachidonic acid by human neutrophils

1984 • 75 citations

Studies on porcine arachidonate 12-lipoxygenase using its monoclonal antibodies.

1986 • 57 citations

The lipoxins. Stereochemical identification and determination of their biosynthesis.

1985 • 54 citations

Lipoxin synthesis by arachidonate 5-lipoxygenase purified from porcine leukocytes

1987 • 53 citations

Regional distribution of prostaglandin endoperoxide synthase studied by enzyme-linked immunoassay using monoclonal antibodies

1986 • 26 citations

Arachidonate 5-lipoxygenase of porcine leukocytes studied by enzyme immunoassay using monoclonal antibodies.

1987 • 23 citations

Stereoselective hydrogen abstraction in leukotriene A4 synthesis by purified 5-lipoxygenase of porcine leukocytes

1986 • 20 citations

Platelet Cyclo‐Oxygenase Deficiency in a Japanese

1984 • 10 citations